{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T20:24:40Z","timestamp":1791923080261,"version":"4.3.4"},"reference-count":25,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2024,2,1]],"date-time":"2024-02-01T00:00:00Z","timestamp":1706745600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,2,1]],"date-time":"2024-02-01T00:00:00Z","timestamp":1706745600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,12,24]],"date-time":"2024-12-24T00:00:00Z","timestamp":1734998400000},"content-version":"vor","delay-in-days":327,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["international-journal-of-gynecological-cancer.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["International Journal of Gynecological Cancer"],"published-print":{"date-parts":[[2024,2]]},"DOI":"10.1136\/ijgc-2023-005032","type":"journal-article","created":{"date-parts":[[2023,12,8]],"date-time":"2023-12-08T00:15:42Z","timestamp":1701994542000},"page":"179-187","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":31,"title":["Prognostic value of isolated tumor cells in sentinel lymph nodes in low risk endometrial cancer: results from an international multi-institutional study"],"prefix":"10.1016","volume":"34","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8574-7346","authenticated-orcid":false,"given":"Giuseppe","family":"Cucinella","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gabriella","family":"Schivardi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xun Clare","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mariam","family":"AlHilli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sumer","family":"Wallace","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christoph","family":"Wohlmuth","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8193-5582","authenticated-orcid":false,"given":"Glauco","family":"Baiocchi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nedim","family":"Tokgozoglu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesco","family":"Raspagliesi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7093-6862","authenticated-orcid":false,"given":"Alessandro","family":"Buda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vanna","family":"Zanagnolo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9175-7767","authenticated-orcid":false,"given":"Ignacio","family":"Zapardiel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nisha","family":"Jagasia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1232-673X","authenticated-orcid":false,"given":"Robert","family":"Giuntoli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ariel","family":"Glickman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michele","family":"Peiretti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maximilian","family":"Lanner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8659-8602","authenticated-orcid":false,"given":"Enrique","family":"Chacon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julian","family":"Di Guilmi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Augusto","family":"Pereira","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Enora","family":"Laas-Faron","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ami","family":"Fishman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Caroline C","family":"Nitschmann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3205-0128","authenticated-orcid":false,"given":"Katherine","family":"Kurnit","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kristen","family":"Moriarty","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amy","family":"Joehlin-Price","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brittany","family":"Lees","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Allan","family":"Covens","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Louise","family":"De Brot","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0936-552X","authenticated-orcid":false,"given":"Cagatay","family":"Taskiran","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giorgio","family":"Bogani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fabio","family":"Landoni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9404-0596","authenticated-orcid":false,"given":"Tommaso","family":"Grassi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cristiana","family":"Paniga","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8535-4059","authenticated-orcid":false,"given":"Francesco","family":"Multinu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3778-8666","authenticated-orcid":false,"given":"Luigi Antonio","family":"De Vitis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alicia","family":"Hern\u00e1ndez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Spyridon","family":"Mastroyannis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Khaled","family":"Ghoniem","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vito","family":"Chiantera","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maryam","family":"Shahi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Angela J","family":"Fought","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michaela","family":"McGree","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8059-1602","authenticated-orcid":false,"given":"Andrea","family":"Mariani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9413-316X","authenticated-orcid":false,"given":"Gretchen","family":"Glaser","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1136\/ijgc-2023-005032_bb0010","first-page":"209","article-title":"Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries","volume":"71","author":"Sung","year":"2021","journal-title":"CA Cancer J Clin"},{"key":"10.1136\/ijgc-2023-005032_bb0015","first-page":"7","article-title":"Cancer statistics, 2020","volume":"70","author":"Siegel","year":"2020","journal-title":"CA Cancer J Clin"},{"key":"10.1136\/ijgc-2023-005032_bb0020","doi-asserted-by":"crossref","first-page":"170","DOI":"10.6004\/jnccn.2018.0006","article-title":"Uterine neoplasms, version 1.2018, NCCN clinical practice guidelines in oncology","volume":"16","author":"Koh","year":"2018","journal-title":"J Natl Compr Canc Netw"},{"key":"10.1136\/ijgc-2023-005032_bb0025","doi-asserted-by":"crossref","first-page":"394","DOI":"10.1016\/j.ygyno.2015.12.028","article-title":"Comparison of a sentinel lymph node and a selective lymphadenectomy algorithm in patients with endometrioid endometrial carcinoma and limited myometrial invasion","volume":"140","author":"Zahl Eriksson","year":"2016","journal-title":"Gynecol Oncol"},{"key":"10.1136\/ijgc-2023-005032_bb0030","doi-asserted-by":"crossref","first-page":"619","DOI":"10.1016\/j.ygyno.2020.03.025","article-title":"Incidence of pelvic lymph node metastasis using modern FIGO staging and sentinel lymph node mapping with ultrastaging in surgically staged patients with endometrioid and serous endometrial carcinoma","volume":"157","author":"Mueller","year":"2020","journal-title":"Gynecol Oncol"},{"key":"10.1136\/ijgc-2023-005032_bb0035","doi-asserted-by":"crossref","first-page":"670","DOI":"10.1016\/j.ygyno.2019.02.027","article-title":"Low-volume disease in endometrial cancer: the role of micrometastasis and isolated tumor cells","volume":"153","author":"Bogani","year":"2019","journal-title":"Gynecol Oncol"},{"key":"10.1136\/ijgc-2023-005032_bb0040","doi-asserted-by":"crossref","first-page":"384","DOI":"10.1016\/S1470-2045(17)30068-2","article-title":"A comparison of sentinel lymph node biopsy to lymphadenectomy for endometrial cancer staging (FIRES trial): a multicentre, prospective, cohort study","volume":"18","author":"Rossi","year":"2017","journal-title":"Lancet Oncol"},{"key":"10.1136\/ijgc-2023-005032_bb0045","doi-asserted-by":"crossref","first-page":"1394","DOI":"10.1016\/S1470-2045(18)30448-0","article-title":"Near-infrared fluorescence for detection of sentinel lymph nodes in women with cervical and uterine cancers (FILM): a randomised, phase 3, multicentre, non-inferiority trial","volume":"19","author":"Frumovitz","year":"2018","journal-title":"Lancet Oncol"},{"key":"10.1136\/ijgc-2023-005032_bb0050","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1016\/j.ejogrb.2022.05.014","article-title":"Assessing the role of low volume disease in endometrial cancer","volume":"274","author":"Bogani","year":"2022","journal-title":"Eur J Obstet Gynecol Reprod Biol"},{"key":"10.1136\/ijgc-2023-005032_bb0055","doi-asserted-by":"crossref","first-page":"590","DOI":"10.1016\/j.ygyno.2021.06.031","article-title":"Oncologic outcomes of endometrial cancer in patients with low-volume metastasis in the sentinel lymph nodes: an international multi-institutional study","volume":"162","author":"Ghoniem","year":"2021","journal-title":"Gynecol Oncol"},{"key":"10.1136\/ijgc-2023-005032_bb0060","doi-asserted-by":"crossref","first-page":"1165","DOI":"10.1097\/IGC.0000000000001016","article-title":"Low-volume lymph node metastases in endometrial carcinoma","volume":"27","author":"Clinton","year":"2017","journal-title":"Int J Gynecol Cancer"},{"key":"10.1136\/ijgc-2023-005032_bb0065","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1016\/j.ijgo.2009.02.012","article-title":"Revised FIGO staging for carcinoma of the vulva, cervix, and endometrium","volume":"105","author":"Pecorelli","year":"2009","journal-title":"Int J Gynaecol Obstet"},{"key":"10.1136\/ijgc-2023-005032_bb0070","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1002\/ijgo.14923","article-title":"FIGO staging of endometrial cancer: 2023","volume":"162","author":"Berek","year":"2023","journal-title":"Int J Gynaecol Obstet"},{"key":"10.1136\/ijgc-2023-005032_bb0075","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1016\/j.ygyno.2018.02.021","article-title":"Lymphnode staging update in the American Joint Committee on Cancer, 8th edition cancer staging manual","volume":"150","author":"Olawaiye","year":"2018","journal-title":"Gynecol Oncol"},{"key":"10.1136\/ijgc-2023-005032_bb0080","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1016\/j.ygyno.2021.02.017","article-title":"Sentinel lymph node (SLN) isolated tumor cells (ITCs) in otherwise stage I\/II endometrioid endometrial cancer: to treat or not to treat?","volume":"161","author":"Backes","year":"2021","journal-title":"Gynecol Oncol"},{"key":"10.1136\/ijgc-2023-005032_bb0085","doi-asserted-by":"crossref","first-page":"240","DOI":"10.1016\/j.ygyno.2017.05.024","article-title":"Isolated tumor cells identified by sentinel lymph node mapping in endometrial cancer: does adjuvant treatment matter?","volume":"146","author":"Plante","year":"2017","journal-title":"Gynecol Oncol"},{"key":"10.1136\/ijgc-2023-005032_bb0090","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1136\/ijgc-2019-000934","article-title":"Retrospective detection of isolated tumor cells by immunohistochemistry in sentinel lymph node biopsy performed for endometrial carcinoma: is there clinical significance?","volume":"30","author":"Goebel","year":"2020","journal-title":"Int J Gynecol Cancer"},{"key":"10.1136\/ijgc-2023-005032_bb0095","doi-asserted-by":"crossref","first-page":"1653","DOI":"10.1245\/s10434-015-5040-z","article-title":"Low-volume lymph node metastasis discovered during sentinel lymph node mapping for endometrial carcinoma","volume":"23","author":"St Clair","year":"2016","journal-title":"Ann Surg Oncol"},{"key":"10.1136\/ijgc-2023-005032_bb0100","doi-asserted-by":"crossref","first-page":"1272","DOI":"10.1007\/s12094-019-02249-x","article-title":"Oncologic impact of micrometastases or isolated tumor cells in sentinel lymph nodes of patients with endometrial cancer: a meta-analysis","volume":"22","author":"G\u00f3mez-Hidalgo","year":"2020","journal-title":"Clin Transl Oncol"},{"key":"10.1136\/ijgc-2023-005032_bb0105","doi-asserted-by":"crossref","DOI":"10.3802\/jgo.2016.27.e1","article-title":"Isolated tumor cells and micrometastases in regional lymph nodes in stage I to II endometrial cancer","volume":"27","author":"Todo","year":"2016","journal-title":"J Gynecol Oncol"},{"key":"10.1136\/ijgc-2023-005032_bb0110","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1136\/ijgc-2020-002230","article-title":"ESGO\/ESTRO\/ESP guidelines for the management of patients with endometrial carcinoma","volume":"31","author":"Concin","year":"2021","journal-title":"Int J Gynecol Cancer"},{"key":"10.1136\/ijgc-2023-005032_bb0115","doi-asserted-by":"crossref","first-page":"1742","DOI":"10.1016\/j.ejca.2015.05.015","article-title":"Substantial lymph-vascular space invasion (LVSI) is a significant risk factor for recurrence in endometrial cancer--A pooled analysis of PORTEC 1 and 2 trials","volume":"51","author":"Bosse","year":"2015","journal-title":"Eur J Cancer"},{"key":"10.1136\/ijgc-2023-005032_bb0120","article-title":"2022-RA-987-ESGO molecular characterization of endometrial cancer with low volume metastasis in the sentinel lymph node: a multicentric international study","volume":"32","author":"Schivardi","year":"2022","journal-title":"BMJ Specialist Journals"},{"key":"10.1136\/ijgc-2023-005032_bb0125","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0195877","article-title":"One-step nucleic acid amplification (OSNA): a fast molecular test based on CK19 mRNA concentration for assessment of lymph-nodes metastases in early stage endometrial cancer","volume":"13","author":"Fanfani","year":"2018","journal-title":"PLoS One"},{"key":"10.1136\/ijgc-2023-005032_bb0130","doi-asserted-by":"crossref","first-page":"1063","DOI":"10.1136\/ijgc-2023-004346","article-title":"Evaluation of the one-step nucleic acid amplification method for rapid detection of lymph node metastases in endometrial cancer: prospective, multicenter, comparative study","volume":"33","author":"La Fera","year":"2023","journal-title":"Int J Gynecol Cancer"}],"container-title":["International Journal of Gynecological Cancer"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1048891X24221691?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1048891X24221691?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/ijgc-2023-005032","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,30]],"date-time":"2025-10-30T17:11:43Z","timestamp":1761844303000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1048891X24221691"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,2]]},"references-count":25,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2024,2]]}},"alternative-id":["S1048891X24221691"],"URL":"https:\/\/doi.org\/10.1136\/ijgc-2023-005032","relation":{},"ISSN":["1048-891X"],"issn-type":[{"value":"1048-891X","type":"print"}],"subject":[],"published":{"date-parts":[[2024,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Prognostic value of isolated tumor cells in sentinel lymph nodes in low risk endometrial cancer: results from an international multi-institutional study","name":"articletitle","label":"Article Title"},{"value":"International Journal of Gynecological Cancer","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1136\/ijgc-2023-005032","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 IGCS and ESGO 2024. No commercial re-use. See rights and permissions. Published by BMJ.","name":"copyright","label":"Copyright"}]}}