{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T01:37:46Z","timestamp":1787017066355,"version":"build-2736575974"},"reference-count":23,"publisher":"BMJ","issue":"7","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Clin Pathol"],"accepted":{"date-parts":[[2012,4,23]]},"published-print":{"date-parts":[[2012,7]]},"abstract":"<jats:p>MRI is an effective tool for detection of ovarian neoplastic lesions. However, there are no highly specific radiological features that differentiate primary from metastatic ovarian masses. Histological diagnosis preoperatively is not always possible as there is a risk of disseminating an otherwise early stage primary ovarian cancer. The preoperative diagnosis of an ovarian lesion is therefore heavily dependent on the radiological features. The radiologist must rely on a combination of knowing the natural history of any known primary cancer, together with the radiological features such as bilaterality, mucinous appearance, pseudomyxoma as well as the clinical progress of the primary tumour in order to evaluate and predict the likelihood of metastatic disease. Even if a non-ovarian primary cancer is known, an ovarian mass cannot always be assumed to be a secondary lesion. Some tumours, such as BRAC-positive breast cancer, are known to have a high rate of concomitant primary ovarian cancer. Conversely, other tumours, such as gastric and appendiceal cancer, are known to have a high rate of ovarian metastatic disease. However, histology remains the only true way to determine an ovarian metastasis from a primary lesion.<\/jats:p>","DOI":"10.1136\/jclinpath-2011-200390","type":"journal-article","created":{"date-parts":[[2012,6,28]],"date-time":"2012-06-28T11:14:40Z","timestamp":1340882080000},"page":"585-590","source":"Crossref","is-referenced-by-count":32,"title":["Radiological manifestations of metastasis to the ovary"],"prefix":"10.1136","volume":"65","author":[{"given":"Fredric","family":"Willmott","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kader Abdel","family":"Allouni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea","family":"Rockall","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2012,6,28]]},"reference":[{"key":"2025092502131672000_65.7.585.1","doi-asserted-by":"crossref","first-page":"1297","DOI":"10.2214\/ajr.180.5.1801297","article-title":"Characterization of adnexal mass lesions on MR imaging","volume":"180","author":"Sohaib","year":"2003","journal-title":"AJR Am J Roentgenol"},{"key":"2025092502131672000_65.7.585.2","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1097\/01.pap.0000213038.85704.e4","article-title":"From Krukenberg to today: the ever present problems posed by metastatic tumors in the ovary. Part 1. historical perspective, general principles, mucinous tumors including the krukenberg tumor","volume":"13","author":"Young","year":"2006","journal-title":"Adv Anat Pathol"},{"key":"2025092502131672000_65.7.585.3","doi-asserted-by":"crossref","first-page":"1305","DOI":"10.1148\/rg.226025033","article-title":"CT and MR imaging of ovarian tumors with emphasis on differential diagnosis","volume":"22","author":"Jung","year":"2002","journal-title":"Radiographics"},{"key":"2025092502131672000_65.7.585.4","doi-asserted-by":"publisher","DOI":"10.1097\/01.rct.0000149958.86165.ca"},{"key":"2025092502131672000_65.7.585.5","doi-asserted-by":"publisher","DOI":"10.4240\/wjgs.v2.i4.109"},{"key":"2025092502131672000_65.7.585.6","doi-asserted-by":"crossref","first-page":"1435","DOI":"10.2214\/ajr.164.6.7754887","article-title":"Krukenberg's tumor of the ovary: MR imaging features","volume":"164","author":"Ha","year":"1995","journal-title":"AJR Am J Roentgenol"},{"key":"2025092502131672000_65.7.585.7","doi-asserted-by":"publisher","DOI":"10.1097\/01.pas.0000176436.26821.8a"},{"key":"2025092502131672000_65.7.585.8","doi-asserted-by":"crossref","unstructured":"Koyama T Mikami Y Saga T . Secondary ovarian tumors: spectrum of CT and MR features with pathologic correlation. Abdom Imaging. Published Online First: 21 February 2007.","DOI":"10.1007\/s00261-007-9186-4"},{"key":"2025092502131672000_65.7.585.9","doi-asserted-by":"publisher","DOI":"10.1097\/00004728-199605000-00013"},{"key":"2025092502131672000_65.7.585.10","doi-asserted-by":"publisher","DOI":"10.1097\/PAP.0b013e3180504abf"},{"key":"2025092502131672000_65.7.585.11","doi-asserted-by":"publisher","DOI":"10.1016\/j.ygyno.2006.09.014"},{"key":"2025092502131672000_65.7.585.12","doi-asserted-by":"crossref","unstructured":"Kondi-Pafiti A Kairi-Vasilatou E Iavazzo C . Metastatic neoplasms of the ovaries: a clinicopathological study of 97 cases. Arch Gynecol Obstet. Published Online First: 11 February 2011.","DOI":"10.1007\/s00404-011-1847-4"},{"key":"2025092502131672000_65.7.585.13","doi-asserted-by":"publisher","DOI":"10.1016\/S0090-8258(03)00075-1"},{"key":"2025092502131672000_65.7.585.14","doi-asserted-by":"publisher","DOI":"10.1006\/gyno.2001.6316"},{"key":"2025092502131672000_65.7.585.15","doi-asserted-by":"publisher","DOI":"10.1097\/PAS.0b013e3181758831"},{"key":"2025092502131672000_65.7.585.16","first-page":"315","article-title":"The study of ovarian metastasis in uterine cancer","volume":"44","author":"Aida","year":"1992","journal-title":"Nihon Sanka Fujinka Gakkai Zasshi"},{"key":"2025092502131672000_65.7.585.17","doi-asserted-by":"publisher","DOI":"10.1016\/0090-8258(91)90253-2"},{"key":"2025092502131672000_65.7.585.18","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1016\/0002-9378(92)91828-X","article-title":"Ovarian metastases in stage IB carcinoma of the cervix: a gynecologic oncology group study","volume":"166","author":"Sutton","year":"1992","journal-title":"Am J Obstet Gynecol"},{"key":"2025092502131672000_65.7.585.19","doi-asserted-by":"publisher","DOI":"10.1006\/gyno.1999.5442"},{"key":"2025092502131672000_65.7.585.20","doi-asserted-by":"publisher","DOI":"10.1097\/01.pas.0000152136.81771.12"},{"key":"2025092502131672000_65.7.585.21","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-08-0373"},{"key":"2025092502131672000_65.7.585.22","first-page":"1519","article-title":"Synchronous endometrial and ovarian carcinomas: analysis of genetic relationship of the tumors","volume":"27","author":"Nishimura","year":"2005","journal-title":"Int J Oncol"},{"key":"2025092502131672000_65.7.585.23","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1097\/AOG.0b013e3181a94568","article-title":"Stage IIIA endometrial carcinoma: outcome and predictors of survival","volume":"114","author":"Bansal","year":"2009","journal-title":"Obstet Gynecol"}],"container-title":["Journal of Clinical Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/jclinpath-2011-200390","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,9,25]],"date-time":"2025-09-25T09:14:05Z","timestamp":1758791645000},"score":1,"resource":{"primary":{"URL":"https:\/\/jcp.bmj.com\/lookup\/doi\/10.1136\/jclinpath-2011-200390"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,6,28]]},"references-count":23,"journal-issue":{"issue":"7","published-online":{"date-parts":[[2012,6,28]]},"published-print":{"date-parts":[[2012,7]]}},"alternative-id":["10.1136\/jclinpath-2011-200390"],"URL":"https:\/\/doi.org\/10.1136\/jclinpath-2011-200390","relation":{},"ISSN":["0021-9746","1472-4146"],"issn-type":[{"value":"0021-9746","type":"print"},{"value":"1472-4146","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,6,28]]}}}