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We reviewed the immunomarkers useful in gynaecological pathology according to literature revision, our personal experience and research findings. We discuss the application of immunohistochemistry to reach the most accurate diagnosis in morphologically equivocal cases of gynaecological pathology and present the appropriate panel of immunomarkers in the most common scenarios of gynaecological pathology. This short review provides an updated overview of the essential immunohistochemical markers currently used in the diagnostics of gynaecological malignancies along with their molecular rationale.<\/jats:p>","DOI":"10.1136\/jclinpath-2017-204787","type":"journal-article","created":{"date-parts":[[2017,11,28]],"date-time":"2017-11-28T12:10:16Z","timestamp":1511871016000},"page":"98-109","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":16,"title":["Diagnostic immunohistochemistry in gynaecological neoplasia: a brief survey of the most common scenarios"],"prefix":"10.1136","volume":"71","author":[{"given":"Elisabetta","family":"Kuhn","sequence":"first","affiliation":[{"name":"Pathology Unit, Arcispedale Santa Maria Nuova\u2013IRCCS, Reggio Emilia, Italy"},{"name":"Department of Morphology, Surgery and Experimental Medicine, University of Ferrara, Ferrara, Italy"},{"name":"Laboratory of Technology for Advanced Therapies (LTTA), University of Ferrara, Ferrara, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0136-4271","authenticated-orcid":false,"given":"Ayse","family":"Ayhan","sequence":"additional","affiliation":[{"name":"Departments of Pathology, Hamamatsu and Hiroshima Universities Schools of Medicine, Seirei Mikatahara Hospital, Hamamatsu, Japan"},{"name":"Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2017,11,28]]},"reference":[{"key":"2025112108532629000_71.2.98.1","doi-asserted-by":"crossref","first-page":"430","DOI":"10.1097\/PGP.0000000000000274","article-title":"An immunohistochemical algorithm for ovarian carcinoma typing","volume":"35","author":"K\u00f6bel","year":"2016","journal-title":"Int J Gynecol Pathol"},{"key":"2025112108532629000_71.2.98.2","unstructured":"Kurman RJ , Carcangiu ML , Herrington CS , et al . 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