{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,26]],"date-time":"2025-11-26T05:03:20Z","timestamp":1764133400506,"version":"3.45.0"},"reference-count":10,"publisher":"BMJ","issue":"4","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["J Clin Pathol"],"accepted":{"date-parts":[[2021,1,24]]},"published-print":{"date-parts":[[2022,4]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Epiploic appendages are fatty peritoneal structures on the external surface of the colon that can infarct and become necrotic in situ or autoamputate.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Aims<\/jats:title>\n                    <jats:p>To describe clinicopathological features of infarcted epiploic appendages (IEAs).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We reviewed 52 IEAs from 49 patients, recording numerous clinical and pathological characteristics, which were compared across attached and loose IEAs.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Twenty-seven IEAs were attached, and 23 were loose; location was unclear in 2. Most were incidental; 3 attached cases caused \u2018appendagitis\u2019. Most (31, 60%) had a classic \u2018egg-like\u2019 appearance. Common findings included fat necrosis (84%), calcification (67%) and fibrosis (58%). Attached cases had a larger mean size (1.8 cm vs 1.3 cm, p=0.030) and were more often haemorrhagic (37% vs 4%, p=0.0064) and inflamed (67% vs 13%, p=0.0002). Loose cases were more often necrotic (100% vs 74%, p=0.011).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>IEAs have different morphology whether they remain attached to peritoneum or become necrotic and detached. Attached cases may cause symptoms.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1136\/jclinpath-2021-207411","type":"journal-article","created":{"date-parts":[[2021,3,1]],"date-time":"2021-03-01T13:20:15Z","timestamp":1614604815000},"page":"279-281","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":1,"title":["Clinicopathological differences in attached versus loose infarcted epiploic appendages: an analysis of 52 cases"],"prefix":"10.1136","volume":"75","author":[{"given":"Caroline","family":"Dignan","sequence":"first","affiliation":[{"name":"Department of Pathology and Laboratory Medicine, University of Rochester Medical Center, Rochester, New York, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adya","family":"Senior","sequence":"additional","affiliation":[{"name":"Department of Pathology and Laboratory Medicine, University of Rochester Medical Center, Rochester, New York, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5526-4220","authenticated-orcid":false,"given":"Raul S","family":"Gonzalez","sequence":"additional","affiliation":[{"name":"Department of Pathology, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2021,3,1]]},"reference":[{"key":"2025112110211432000_75.4.279.1","doi-asserted-by":"publisher","DOI":"10.1186\/s13244-019-0715-9"},{"key":"2025112110211432000_75.4.279.2","doi-asserted-by":"publisher","DOI":"10.4240\/wjgs.v11.i8.342"},{"key":"2025112110211432000_75.4.279.3","first-page":"511","article-title":"Infarcted epiploic appendage of the vermiform appendix masquerading as acute appendicitis","volume":"59","author":"Magnuson","year":"2006","journal-title":"S D Med"},{"key":"2025112110211432000_75.4.279.4","doi-asserted-by":"crossref","first-page":"1552","DOI":"10.1007\/s00261-017-1355-5","article-title":"Epiploic appendagitis: 7-year experience and relationship with visceral obesity","volume":"43","author":"Nugent","year":"2018","journal-title":"Abdom Radiol"},{"key":"2025112110211432000_75.4.279.5","doi-asserted-by":"publisher","DOI":"10.1007\/s003300050942"},{"key":"2025112110211432000_75.4.279.6","doi-asserted-by":"crossref","DOI":"10.1186\/1752-1947-5-297","article-title":"'Boiled egg' in the peritoneal cavity-a giant peritoneal loose body in a 64-year-old man: a case report","volume":"5","author":"Sewkani","year":"2011","journal-title":"J Med Case Rep"},{"key":"2025112110211432000_75.4.279.7","doi-asserted-by":"publisher","DOI":"10.1097\/00004836-200605000-00012"},{"key":"2025112110211432000_75.4.279.8","doi-asserted-by":"publisher","DOI":"10.1097\/00007611-198603000-00030"},{"key":"2025112110211432000_75.4.279.9","doi-asserted-by":"publisher","DOI":"10.1148\/radiographics.12.1.1734482"},{"key":"2025112110211432000_75.4.279.10","doi-asserted-by":"publisher","DOI":"10.1007\/s004280050159"}],"container-title":["Journal of Clinical Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/jclinpath-2021-207411","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,11,21]],"date-time":"2025-11-21T18:21:24Z","timestamp":1763749284000},"score":1,"resource":{"primary":{"URL":"https:\/\/jcp.bmj.com\/lookup\/doi\/10.1136\/jclinpath-2021-207411"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,3,1]]},"references-count":10,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2022,3,17]]},"published-print":{"date-parts":[[2022,4]]}},"alternative-id":["10.1136\/jclinpath-2021-207411"],"URL":"https:\/\/doi.org\/10.1136\/jclinpath-2021-207411","relation":{},"ISSN":["0021-9746","1472-4146"],"issn-type":[{"type":"print","value":"0021-9746"},{"type":"electronic","value":"1472-4146"}],"subject":[],"published":{"date-parts":[[2021,3,1]]}}}