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We also discuss the gross evaluation and sectioning of small therapeutic resections, along with a systematic approach and rationale when grossing and submitting histological sections from larger oncological resections from the luminal GI tract. Selected site-specific considerations, for example, grossing treated rectal and oesophageal cancers or taking sections from mucinous tumours of the appendix, among others, are also discussed.<\/jats:p>","DOI":"10.1136\/jcp-2023-208981","type":"journal-article","created":{"date-parts":[[2024,2,19]],"date-time":"2024-02-19T05:10:21Z","timestamp":1708319421000},"page":"169-176","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":4,"title":["Essentials of macroscopic evaluation of specimens from gastrointestinal tract"],"prefix":"10.1136","volume":"77","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7020-9948","authenticated-orcid":false,"given":"Monika","family":"Vyas","sequence":"first","affiliation":[{"name":"Department of Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0351-2859","authenticated-orcid":false,"given":"Dipti M","family":"Karamchandani","sequence":"additional","affiliation":[{"name":"Department of Pathology, Division of Anatomic Pathology, UT Southwestern Medical School, Dallas, Texas, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2024,2,19]]},"reference":[{"key":"2025121220242317000_77.3.169.1","unstructured":"Burgart LJ , Chopp WV , Jain D . 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