{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,26]],"date-time":"2025-09-26T00:11:59Z","timestamp":1758845519094,"version":"3.44.0"},"reference-count":17,"publisher":"BMJ","issue":"7","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["J Clin Pathol"],"accepted":{"date-parts":[[2024,10,27]]},"published-print":{"date-parts":[[2025,7]]},"abstract":"<jats:sec>\n                  <jats:title>Aim<\/jats:title>\n                  <jats:p>Primary malignant melanomas in the bladder or urethra are exceedingly rare. Diagnosing these tumours presents substantial challenges due to their close resemblance in gross appearance and histology to urothelial carcinomas.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>A retrospective review of our department archives from 2000 to 2023 identified four cases of primary malignant melanoma in the urinary tract. Demographic and clinical data were extracted from electronic medical records.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>This retrospective case series investigates the clinical presentations, histopathological characteristics, immunohistochemical profiles and molecular features of four unique cases of primary malignant melanoma in the bladder or urethra.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion<\/jats:title>\n                  <jats:p>Our analysis aims to deepen the understanding of the diagnostic and management strategies for this extremely rare disease.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1136\/jcp-2024-209684","type":"journal-article","created":{"date-parts":[[2024,11,21]],"date-time":"2024-11-21T13:35:20Z","timestamp":1732196120000},"page":"443-448","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":0,"title":["Primary melanoma of the urinary tract: a clinicopathological study of cases and literature review"],"prefix":"10.1136","volume":"78","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4033-9856","authenticated-orcid":false,"given":"Lisha","family":"Wang","sequence":"first","affiliation":[{"name":"Department of Pathology, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohammed","family":"Wali","sequence":"additional","affiliation":[{"name":"Department of Pathology, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-4499-5221","authenticated-orcid":false,"given":"Yue","family":"Sun","sequence":"additional","affiliation":[{"name":"Department of Pathology, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2024,11,21]]},"reference":[{"key":"2025092502065032000_78.7.443.1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-0142(19981015)83:8<1664::AID-CNCR23>3.0.CO;2-G"},{"key":"2025092502065032000_78.7.443.2","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1016\/j.urolonc.2015.11.009","article-title":"Primary genitourinary melanoma: Epidemiology and disease-specific survival in a large population-based cohort","volume":"34","author":"Sanchez","year":"2016","journal-title":"Urol Oncol"},{"key":"2025092502065032000_78.7.443.3","doi-asserted-by":"publisher","DOI":"10.1016\/j.prp.2020.153095"},{"key":"2025092502065032000_78.7.443.4","doi-asserted-by":"crossref","DOI":"10.1038\/s41467-020-15546-9","article-title":"Pre-clinical modeling of cutaneous melanoma","volume":"11","author":"Rebecca","year":"2020","journal-title":"Nat Commun"},{"key":"2025092502065032000_78.7.443.5","doi-asserted-by":"publisher","DOI":"10.1080\/07357900701781762"},{"key":"2025092502065032000_78.7.443.6","first-page":"5122","article-title":"Primary melanoma of the bladder: a case report and review of the literature","volume":"25","author":"Quaquarini","year":"2021","journal-title":"Eur Rev Med Pharmacol Sci"},{"key":"2025092502065032000_78.7.443.7","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2015.05.044"},{"key":"2025092502065032000_78.7.443.8","doi-asserted-by":"publisher","DOI":"10.1038\/nature22071"},{"key":"2025092502065032000_78.7.443.9","doi-asserted-by":"publisher","DOI":"10.18632\/oncotarget.16542"},{"key":"2025092502065032000_78.7.443.10","doi-asserted-by":"publisher","DOI":"10.1016\/j.ygyno.2014.04.056"},{"key":"2025092502065032000_78.7.443.11","doi-asserted-by":"publisher","DOI":"10.1097\/PGP.0000000000000636"},{"key":"2025092502065032000_78.7.443.12","doi-asserted-by":"publisher","DOI":"10.1002\/onco.13639"},{"key":"2025092502065032000_78.7.443.13","article-title":"Melanoma of the urinary bladder: a review of the literature","volume":"2014","author":"Venyo","year":"2014","journal-title":"Surg Res Pract"},{"key":"2025092502065032000_78.7.443.14","doi-asserted-by":"publisher","DOI":"10.1097\/CMR.0000000000000300"},{"key":"2025092502065032000_78.7.443.15","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2010.12.004"},{"key":"2025092502065032000_78.7.443.16","doi-asserted-by":"crossref","first-page":"291","DOI":"10.3233\/BLC-211633","article-title":"Urethral Melanoma - 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