{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,14]],"date-time":"2025-12-14T08:00:19Z","timestamp":1765699219188,"version":"3.48.0"},"reference-count":63,"publisher":"BMJ","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Clin Pathol"],"published-print":{"date-parts":[[1961,11]]},"abstract":"<jats:p>A sibship with four cases of hereditary elliptocytic anaemia is described. The condition in this family may have arisen as a mutation in the mother of the sibship; affected members were unable to taste phenylthiocarbamide while normal members were tasters.<\/jats:p>\n                  <jats:p>\n                    Experiments with\n                    <jats:sup>32<\/jats:sup>\n                    P-orthophosphate\n                    <jats:italic>in vitro<\/jats:italic>\n                    did not show any evidence of biochemical upset as found in hereditary spherocytosis; thus a combination of congenital spherocytosis and elliptocytosis cannot be supported as the cause of the haemolytic state. Clinical evidence of haemolytic disease was accompanied by a tendency to excessive lysis\n                    <jats:italic>in vitro.<\/jats:italic>\n                  <\/jats:p>\n                  <jats:p>Infection may play a part in the precipitation of anaemic crises in this as in other hereditary haemolytic anaemias.<\/jats:p>","DOI":"10.1136\/jcp.14.6.615","type":"journal-article","created":{"date-parts":[[2007,6,9]],"date-time":"2007-06-09T00:50:46Z","timestamp":1181350246000},"page":"615-621","source":"Crossref","is-referenced-by-count":8,"title":["Hereditary elliptocytic anaemia"],"prefix":"10.1136","volume":"14","author":[{"given":"R. J. L.","family":"Davidson","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"W. T.","family":"Strauss","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[1961,11,1]]},"reference":[{"key":"ref_1","first-page":"184","volume":"98","author":"Avery, M.E.","year":"1956","unstructured":"Avery, M. E. (1956). Bull. Johns Hopk. Hosp., 98, 184.","journal-title":"Bull. Johns Hopk. Hosp"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"388","DOI":"10.1001\/archinte.1914.00070150101006","volume":"14","author":"Bishop, F.W.","year":"1914","unstructured":"Bishop, F. W. (1914). Arch. intern. Med., 14, 388.","journal-title":"Arch. intern. Med"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"316","DOI":"10.1136\/jcp.11.4.316","volume":"11","author":"Blackburn, E.K.; Jordan, A.; Lytle, W.J.; Swan, H.T.; Tudhope, G.R.","year":"1958","unstructured":"Blackburn, E. K., Jordan, A., Lytle, W. J., Swan, H. T., and Tudhope, G. R. (1958). J. clin. Path., 11, 316.","journal-title":"J. clin. Path"},{"key":"ref_4","author":"Breuer, M.; De Vries, A.; Peket, L.; Matoth, Y.","year":"1958","unstructured":"Breuer, M., De Vries, A., Peket, L., and Matoth, Y. (1958). Proc.","journal-title":"Proc"},{"key":"ref_5","first-page":"749","volume":"4","author":"th-int-Congr-int-Soc; Hematology, Boston","year":"1956","unstructured":"th int. Congr. int. Soc. Hematology, Boston, 1956, p. 749. Grune and Stratton, New York. Campanacci, L., Torlontano, G., Tonietti, G., and Conti, C. (1960). Minerva. nucleare (Torino), 4, 18.","journal-title":"Minerva. nucleare (Torino)"},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1111\/j.1469-1809.1960.tb01739.x","volume":"24","author":"Clarke, C.A.; Donohoe, W.T.A.; Finn, R.; McConnell, R.B.; Sheppard, P.M.; Nicol, D.S.H.","year":"1960","unstructured":"Clarke, C. A., Donohoe, W. T. A., Finn, R., McConnell, R. B., Sheppard, P. M., and Nicol, D. S. H. (1960). Ann. hum. Genet., 24, 283.","journal-title":"Ann. hum. Genet"},{"key":"ref_7","article-title":"The Haemolytic Anaemias, Congenital and Acquired","author":"Dacie, J.V.","year":"1954","unstructured":"Dacie, J. V. (1954). The Haemolytic Anaemias, Congenital and Acquired. Churchill, London. (1960a, b, c, d, e). Ibid, 2nd ed. Pt 1. Churchill, London.","edition":"2nd ed"},{"key":"ref_8","first-page":"79","volume":"22","author":"Mollison, P.L.; Richardson, N.; Selwyn, J.G.; Shapiro, L.","year":"1953","unstructured":"Mollison, P. L., Richardson, N., Selwyn, J. G., and Shapiro, L. (1953). Quart. J. Med., 22, 79.","journal-title":"Quart. J. Med"},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"1381","DOI":"10.1182\/blood.V3.12.1381.1381","volume":"3","author":"Dameshek, W.; Bloom, M.L.","year":"1948","unstructured":"Dameshek, W., and Bloom, M. L. (1948). Blood, 3, 1381.","journal-title":"Blood"},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"469","DOI":"10.1126\/science.19.481.469","volume":"19","author":"Dresbach, M.","year":"1904","unstructured":"Dresbach, M. (1904). Science, 19, 469.","journal-title":"Science"},{"key":"ref_11","first-page":"33","volume":"29","author":"Ducla-Soares, A.; Parreira, F.","year":"1958","unstructured":"Ducla-Soares, A., and Parreira, F. (1958). Sang., 29, 33.","journal-title":"Sang"},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1001\/archinte.1956.00250190017001","volume":"97","author":"A. M. A.","year":"1956","unstructured":"Emerson, C. P. Jr., Shen, S. C., Ham, T. H., Fleming, E. M., and Castle, W. B. (1956). A.M.A. Arch. intern. Med., 97, 1.","journal-title":"Arch. intern. Med"},{"key":"ref_13","first-page":"237","volume":"21","author":"Gasser, C.","year":"1950","unstructured":"Gasser, C. (1950). Sang, 21, 237.","journal-title":"Sang"},{"key":"ref_14","first-page":"214","article-title":"Die hwnolytischen Syndrome im Kindesalter","author":"Gasser, C.","year":"1951","unstructured":"Gasser, C. (1951). Die hwnolytischen Syndrome im Kindesalter, p. 214. Thieme, Stuttgart."},{"key":"ref_15","first-page":"272","volume":"17","author":"Goodall, H.B.; Hendry, D.W.; Lawler, S.D.; Stephen, S.A.","year":"1953","unstructured":"Goodall, H. B., Hendry, D. W., Lawler, S. D., and Stephen, S. A. (1953). Ann. Eugen. (Lond.), 17, 272. __, -,-(1954). Ibid, 18, 325.","journal-title":"Ann. Eugen. (Lond.)"},{"key":"ref_16","first-page":"925","volume":"34","author":"Holst-Larsen, T.","year":"1947","unstructured":"Holst-Larsen, T. (1947). Nord. Med., 34, 925.","journal-title":"Nord. Med"},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"1162","DOI":"10.7326\/0003-4819-2-11-1162","volume":"2","author":"Hunter, W.C.; Adams, R.B.","year":"1929","unstructured":"Hunter, W. C., and Adams, R. B. (1929). Ann. intern. Med., 2, 1162.","journal-title":"Ann. intern. Med"},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1007\/978-3-642-90688-6_8","volume":"55","author":"Lambrecht, K.","year":"1938","unstructured":"Lambrecht, K. (1938). Ergebn. inn. Med. Kinderheilk., 55, 295.","journal-title":"Ergebn. inn. Med. Kinderheilk"},{"key":"ref_19","first-page":"328","volume":"18","author":"Lawler, S.D.; Sandler, M.","year":"1954","unstructured":"Lawler, S. D., and Sandler, M. (1954). Ann. Eugen. (Lond.), 18, 328.","journal-title":"Ann. Eugen. (Lond.)"},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"582","DOI":"10.1016\/S0140-6736(49)90922-8","volume":"1","author":"Lendval, J.","year":"1949","unstructured":"Lendval, J. (1949). Lancet, 1, 582.","journal-title":"Lancet"},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1111\/j.0954-6820.1955.tb10263.x","volume":"151","author":"Letman, H.","year":"1955","unstructured":"Letman, H. (1955). Acta med. scand., 151, 41.","journal-title":"Acta med. scand"},{"key":"ref_22","first-page":"67","volume":"15","author":"Lipton, E.L.","year":"1955","unstructured":"Lipton, E. L. (1955). Pediatrics, 15, 67.","journal-title":"Pediatrics"},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"790","DOI":"10.1172\/JCI102949","volume":"33","author":"Marshall, R.A.; Bird, R.M.; Bailey, H.K.; Beckner, E.","year":"1954","unstructured":"Marshall, R. A., Bird, R. M., Bailey, H. K., and Beckner, E. (1954). J. clin. Invest., 33, 790.","journal-title":"J. clin. Invest"},{"key":"ref_24","first-page":"2351","volume-title":"Handbook of Hematology","volume":"3","author":"Mason, V.R.","year":"1938","unstructured":"Mason, V. R. (1938). In Handbook of Hematology, Vol. 3, ed. H. Downey, p. 2351. Hoeber, New York."},{"key":"ref_25","first-page":"80","volume":"8","author":"Morton, N.E.","year":"1956","unstructured":"Morton, N. E. (1956). Amer. J. hum. Genet., 8, 80.","journal-title":"Amer. J. hum. Genet"},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1182\/blood.V9.1.57.57","volume":"9","author":"Motulsky, A.G.; Singer, K.; Crosby, W.H.; Smith, V.","year":"1954","unstructured":"Motulsky, A. G., Singer, K., Crosby, W. H., and Smith, V. (1954). Blood, 9, 57.","journal-title":"Blood"},{"key":"ref_27","first-page":"231","volume":"3","author":"Owren, P.A.","year":"1948","unstructured":"Owren, P. A. (1948). Ibid, 3, 231.","journal-title":"Ibid"},{"key":"ref_28","first-page":"157","volume":"12","author":"Penfold, J.B.; Lipscomb, J.M.","year":"1943","unstructured":"Penfold, J. B., and Lipscomb, J. M. (1943). Quart. J. Med., n.s. 12, 157.","journal-title":"Quart. J. Med"},{"year":"1954","author":"Prankerd, T.A.J.; Altman, K.I.; Young, L.E.","key":"ref_29","unstructured":"Prankerd, T. A. J., Altman, K. I., and Young, L. E. (1954). J. clin."},{"key":"ref_30","first-page":"1268","volume":"34","author":"Ibid","unstructured":"Ibid, 34, 1268."},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"414","DOI":"10.1182\/blood.V9.5.414.414","volume":"9","author":"Selwyn, J.G.; Dacie, J.V.","year":"1954","unstructured":"Selwyn, J. G., and Dacie, J. V. (1954). Blood, 9, 414.","journal-title":"Blood"},{"key":"ref_32","author":"Tabechian, H.; Altman, K.I.; Young, L.E.","year":"1956","unstructured":"Tabechian, H., Altman, K. I., and Young, L. E. (1956). Proc. Soc.","journal-title":"Proc. Soc"},{"key":"ref_33","first-page":"19","volume":"10","author":"Vandepitte, J.; Louis, L.","year":"1955","unstructured":"Vandepitte, J., and Louis, L. (1955). Rev. Hemat., 10, 19.","journal-title":"Rev. Hemat"},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"438","DOI":"10.1001\/archinte.1955.00250090076010","volume":"95","author":"Wilson, H.E.; Long, M.J.","year":"1955","unstructured":"Wilson, H. E., and Long, M. J. (1955). A.M.A. Arch. intern. Med., 95, 438.","journal-title":"Arch. intern. Med"},{"article-title":"Arc\/","year":"1941","key":"ref_35","unstructured":"Wyandt, H., Bancroft, P. M., and Winship, T. 0. (1941). Arc\/."},{"key":"ref_36","doi-asserted-by":"crossref","first-page":"1073","DOI":"10.1182\/blood.V6.11.1073.1073","volume":"6","author":"Young, L.E.; Izzo, M.J.; Platzer, R.F.","year":"1951","unstructured":"Young, L. E., Izzo, M. J., and Platzer, R. F. (1951). Blood, 6, 1073.","journal-title":"Blood"},{"key":"ref_37","article-title":"Broadsheets prepared by the Association of Clinical Pathologists The following broadsheets (new series) are published by the Association of Clinical Pathologists. They may be obtained","volume-title":"The prices include postage, but air mail will be charged extra","author":"Tierney, R.B.H.; Laboratory, Pathological; Street, Boutport; Barnstaple, N.Devon","unstructured":"Broadsheets prepared by the Association of Clinical Pathologists The following broadsheets (new series) are published by the Association of Clinical Pathologists. They may be obtained from Dr. R. B. H. Tierney, Pathological Laboratory, Boutport Street, Barnstaple, N. Devon. The prices include postage, but air mail will be charged extra."},{"key":"ref_38","unstructured":"The Detection of Barbiturates in Blood, Cerebrospinal Fluid, Urine, and Stomach Contents. 1953. L. C. NICKOLLS. IS.","article-title":"The Detection of Barbiturates in Blood, Cerebrospinal Fluid, Urine, and Stomach Contents. 1953. L"},{"article-title":"The Estimation of Carbon Monoxide in Blood. 1953","author":"A, D.","key":"ref_39","unstructured":"The Estimation of Carbon Monoxide in Blood. 1953. D. A. STANLEY. IS."},{"key":"ref_40","article-title":"The Identification of Reducing Substances in Urine by Partition Chromatography on Paper","author":"is, G.B.M.A.N.N.I.N.G.","year":"1953","unstructured":"The Identification of Reducing Substances in Urine by Partition Chromatography on Paper. 1953. G. B. MANNING. is."},{"author":"A, The Paul-Bunnell Test. 1954. R. H.","key":"ref_41","unstructured":"The Paul-Bunnell Test. 1954. R. H. A. SWAIN. Is."},{"article-title":"The Papanicolaou Technique for the Detection of Malignant Cells in Sputum. 1955","author":"F. HAMPSON. Is","key":"ref_42","unstructured":"The Papanicolaou Technique for the Detection of Malignant Cells in Sputum. 1955. F. HAMPSON. Is."},{"article-title":"Mycological Techniques: (1) Collection of Specimens","year":"1956","key":"ref_43","unstructured":"Mycological Techniques: (1) Collection of Specimens. 1956. R. W. RIDDELL. IS."},{"article-title":"Mycological Techniques: (2) Cultural Isolation","year":"1956","key":"ref_44","unstructured":"Mycological Techniques: (2) Cultural Isolation. 1956. R. W. RIDDELL. Is."},{"author":"for Demonstrating L. E. Cells. 1956. J. V. DACIE, Techniques; S, L.","key":"ref_45","unstructured":"Techniques for Demonstrating L.E. Cells. 1956. J. V. DACIE and L. S. SACKER. Is."},{"key":"ref_46","unstructured":"The Identification of Serotypes of Escherichia coli Associated with Infantile Gastro-enteritis. 1956. JOAN TAYLOR. Is.","article-title":"The Identification of Serotypes of Escherichia coli Associated with Infantile Gastro-enteritis. 1956"},{"article-title":"The Determination of Serum Iron and Serum Unsaturated Iron-binding Capacity. 1956","volume-title":"ARTHUR JORDAN. I S.","key":"ref_47","unstructured":"The Determination of Serum Iron and Serum Unsaturated Iron-binding Capacity. 1956. ARTHUR JORDAN. I S."},{"author":"of Pathological Museum Specimens. 1957. L, Preservation","key":"ref_48","unstructured":"Preservation of Pathological Museum Specimens. 1957. L. W. PROGER. 1s."},{"year":"1957","author":"of Whooping-cough, Cultural Diagnosis","key":"ref_49","unstructured":"Cultural Diagnosis of Whooping-cough. 1957. B. W. LACEY. Is."},{"article-title":"GREENBURY","author":"L, The Rose-Waaler Test. 1957. C.","key":"ref_50","unstructured":"The Rose-Waaler Test. 1957. C. L. GREENBURY. Is."},{"article-title":"The Laboratory Diagnosis of Fibrinogen Deficiency. 1958","author":"IS, R.M.H.A.R.D.I.S.T.Y.","key":"ref_51","unstructured":"The Laboratory Diagnosis of Fibrinogen Deficiency. 1958. R. M. HARDISTY. IS."},{"year":"1958","author":"of Porphyrin\/Porphyria, Investigation","key":"ref_52","unstructured":"Investigation of Porphyrin\/Porphyria. 1958. c. RIMINGTON. 1 S."},{"key":"ref_53","unstructured":"Quantitative Determination of Porphobilinogen and Porphyrins in Urine and Faeces. 1958. C. RIMINGTON. ls.","article-title":"Quantitative Determination of Porphobilinogen and Porphyrins in Urine and Faeces. 1958. C. RIMINGTON. ls"},{"author":"of Haemolytic Anaemia. 1959. J. G, Investigation","key":"ref_54","unstructured":"Investigation of Haemolytic Anaemia. 1959. J. G. SELWYN. 1 S."},{"key":"ref_55","article-title":"The Dried Disc Technique for Bacterial Sensitivity Tests","author":"FAIRBROTHER, R.W.","year":"1959","unstructured":"The Dried Disc Technique for Bacterial Sensitivity Tests. 1959. R. W. FAIRBROTHER and J. C. SHERRIS. IS."},{"article-title":"Safe Handling of Radioactive Tissues in the Laboratory and Post-mortem Room. 1959","volume-title":"R. C. CURRAN. Is.","key":"ref_56","unstructured":"Safe Handling of Radioactive Tissues in the Laboratory and Post-mortem Room. 1959. R. C. CURRAN. Is."},{"article-title":"PEARSE I S","author":"E, The Periodic Acid-Schiff Reaction. 1959. A. G.","key":"ref_57","unstructured":"The Periodic Acid-Schiff Reaction. 1959. A. G. E. PEARSE I S."},{"key":"ref_58","volume":"2","author":"C, Daily Fatty Acid Excretion. 1960. A.","unstructured":"Daily Fatty Acid Excretion. 1960. A. C. FRAZER. 2s.","journal-title":"FRAZER"},{"key":"ref_59","volume":"2","author":"H, D.","unstructured":"D. H. COLLINS. 2s.","journal-title":"COLLINS"},{"key":"ref_60","volume":"4","author":"K, E.","unstructured":"E. K. BLACKBURN. 4s.","journal-title":"BLACKBURN"},{"article-title":"CRUICK-SHANK and s. M. STEWART. 2s","author":"Detection of Resistance to Streptomycin, P. A. S.; in Tubercle Bacilli. 1961. R, Isoniazid","key":"ref_61","unstructured":"Detection of Resistance to Streptomycin, P.A.S., and Isoniazid in Tubercle Bacilli. 1961. R. CRUICK-SHANK and s. M. STEWART. 2s."},{"key":"ref_62","volume":"2","author":"of Antistreptolysin 0. 1961. H. GOODER, Titration; 0, R. E.","year":"WILLIAMS.","unstructured":"Titration of Antistreptolysin 0. 1961. H. GOODER and R. E. 0. WILLIAMS. 2s."},{"key":"ref_63","unstructured":"The Estimation of Faecal 'Urobilinogen.' 1961.","article-title":"The Estimation of Faecal 'Urobilinogen.' 1961"}],"container-title":["Journal of Clinical Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/jcp.14.6.615","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,12,14]],"date-time":"2025-12-14T07:59:21Z","timestamp":1765699161000},"score":1,"resource":{"primary":{"URL":"https:\/\/jcp.bmj.com\/lookup\/doi\/10.1136\/jcp.14.6.615"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1961,11]]},"references-count":63,"journal-issue":{"issue":"6","published-online":{"date-parts":[[1961,11,1]]},"published-print":{"date-parts":[[1961,11]]}},"alternative-id":["10.1136\/jcp.14.6.615"],"URL":"https:\/\/doi.org\/10.1136\/jcp.14.6.615","relation":{},"ISSN":["0021-9746","1472-4146"],"issn-type":[{"type":"print","value":"0021-9746"},{"type":"electronic","value":"1472-4146"}],"subject":[],"published":{"date-parts":[[1961,11]]}}}