{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,14]],"date-time":"2025-12-14T14:59:19Z","timestamp":1765724359755,"version":"3.48.0"},"reference-count":10,"publisher":"BMJ","issue":"12","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Clin Pathol"],"published-print":{"date-parts":[[2004,12]]},"abstract":"<jats:p>\n                    <jats:bold>Aim:<\/jats:bold>\n                    To assess the incidence of legionella infection over a 27 month period at a large university hospital.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Material and Methods:<\/jats:bold>\n                    The present retrospective cohort study enrolled patients with legionellosis, defined as those presenting a positive urinary antigen for legionella together with a medical history, clinical findings, and radiological findings consistent with pneumonia. These patients were evaluated to determine the relation between their test results and changes in treatment modalities. A control group of patients with pneumonia but a negative urinary antigen test for legionella were also analysed.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Results:<\/jats:bold>\n                    Twenty seven of 792 assessed patients tested positive for legionella. In 22 of these patients, legionella active antibiotics were administered empirically. In seven patients, the test results prompted a legionella specific treatment, whereas in 12 cases, non-specific antibiotics were stopped within 24 hours. Overall, treatment was altered in more than half of the patients as a result of the test results.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Conclusions:<\/jats:bold>\n                    The urinary antigen may have a direct impact on clinical management of pulmonary legionellosis. However, patient comorbidities and individual clinical judgment are still important for determining the best treatment to be given in each individual case.\n                  <\/jats:p>","DOI":"10.1136\/jcp.2004.018861","type":"journal-article","created":{"date-parts":[[2004,11,24]],"date-time":"2004-11-24T13:12:48Z","timestamp":1101301968000},"page":"1302-1305","source":"Crossref","is-referenced-by-count":23,"title":["Impact of positive legionella urinary antigen test on patient management and improvement of antibiotic use: \n            Table 1"],"prefix":"10.1136","volume":"57","author":[{"given":"J","family":"Garbino","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J-E","family":"Bornand","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"I","family":"U\u00e7kay","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S","family":"Fonseca","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H","family":"Sax","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2004,11,24]]},"reference":[{"doi-asserted-by":"publisher","key":"2025121406563690000_57.12.1302.1","DOI":"10.1056\/NEJM199709043371006"},{"doi-asserted-by":"publisher","key":"2025121406563690000_57.12.1302.2","DOI":"10.1086\/515040"},{"doi-asserted-by":"publisher","key":"2025121406563690000_57.12.1302.3","DOI":"10.1378\/chest.117.2.398"},{"doi-asserted-by":"publisher","key":"2025121406563690000_57.12.1302.4","DOI":"10.1016\/S0002-9343(00)00624-0"},{"doi-asserted-by":"publisher","key":"2025121406563690000_57.12.1302.5","DOI":"10.1086\/380488"},{"key":"2025121406563690000_57.12.1302.6","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1111\/j.1469-0691.1998.tb00079.x","volume":"4","year":"1998","journal-title":"Clin Microbiol Infect"},{"doi-asserted-by":"publisher","key":"2025121406563690000_57.12.1302.7","DOI":"10.1128\/JCM.41.2.838-840.2003"},{"doi-asserted-by":"publisher","key":"2025121406563690000_57.12.1302.8","DOI":"10.1086\/513953"},{"key":"2025121406563690000_57.12.1302.9","first-page":"1191","volume":"39","year":"1994","journal-title":"Respir Care"},{"doi-asserted-by":"publisher","key":"2025121406563690000_57.12.1302.10","DOI":"10.1097\/00007890-200209270-00028"}],"container-title":["Journal of Clinical Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/jcp.2004.018861","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,12,14]],"date-time":"2025-12-14T14:56:42Z","timestamp":1765724202000},"score":1,"resource":{"primary":{"URL":"https:\/\/jcp.bmj.com\/lookup\/doi\/10.1136\/jcp.2004.018861"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2004,11,24]]},"references-count":10,"journal-issue":{"issue":"12","published-online":{"date-parts":[[2004,11,24]]},"published-print":{"date-parts":[[2004,12]]}},"alternative-id":["10.1136\/jcp.2004.018861"],"URL":"https:\/\/doi.org\/10.1136\/jcp.2004.018861","relation":{},"ISSN":["0021-9746","1472-4146"],"issn-type":[{"type":"print","value":"0021-9746"},{"type":"electronic","value":"1472-4146"}],"subject":[],"published":{"date-parts":[[2004,11,24]]}}}