{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,14]],"date-time":"2025-12-14T15:04:10Z","timestamp":1765724650523,"version":"3.48.0"},"reference-count":23,"publisher":"BMJ","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Clin Pathol"],"published-print":{"date-parts":[[2005,5]]},"abstract":"<jats:p>\n                    <jats:bold>Background:<\/jats:bold>\n                    Dietary questionnaire studies have suggested that patients with oesophageal adenocarcinoma are deficient in antioxidants. It is not known whether the same holds true for patients with the precursor lesion, Barrett\u2019s oesophagus.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Aims:<\/jats:bold>\n                    To evaluate the hypothesis that patients with Barrett\u2019s oesophagus are deficient in antioxidants compared with patients without evidence of Barrett\u2019s oesophagus.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Patients and methods:<\/jats:bold>\n                    Plasma antioxidant profiles (copper, selenium, zinc; vitamins A, C, and E; carotenoids) were determined for patients with Barrett\u2019s oesophagus (n \u200a=\u200a 36), patients with erosive oesophagitis (n \u200a=\u200a 32), and patient controls (n \u200a=\u200a 35).\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Results:<\/jats:bold>\n                    Patients with Barrett\u2019s oesophagus had significantly lower plasma concentrations of selenium, vitamin C, \u03b2\u00a0cryptoxanthine, and xanthophyll compared with the other groups.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>Conclusions:<\/jats:bold>\n                    This study confirms the hypothesis that patients with Barrett\u2019s oesophagus are deficient in certain antioxidants.\n                  <\/jats:p>","DOI":"10.1136\/jcp.2004.023721","type":"journal-article","created":{"date-parts":[[2005,4,27]],"date-time":"2005-04-27T16:16:29Z","timestamp":1114618589000},"page":"490-492","source":"Crossref","is-referenced-by-count":11,"title":["A study to determine plasma antioxidant concentrations in patients with Barrett\u2019s oesophagus"],"prefix":"10.1136","volume":"58","author":[{"given":"D M","family":"Clements","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D 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Barrett\u2019s esophagus. In: Castell DO, Richter JE, eds. The esophagus. 3rd ed. Philadelphia: Lippincott Williams & Wilkins, 1999."},{"key":"2025121407002719000_58.5.490.22","doi-asserted-by":"crossref","unstructured":"Bjelakovic G, Nikolova D, Simonetti RG, et al. Antioxidant supplements for preventing gastrointestinal cancers. The Cochrane Database of Systematic Reviews. 2004, Issue 4.","DOI":"10.1002\/14651858.CD004183.pub2"},{"key":"2025121407002719000_58.5.490.23","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1155\/1999\/97140","volume":"11","year":"1999","journal-title":"HPB Surg"}],"container-title":["Journal of Clinical Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/jcp.2004.023721","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,12,14]],"date-time":"2025-12-14T15:00:34Z","timestamp":1765724434000},"score":1,"resource":{"primary":{"URL":"https:\/\/jcp.bmj.com\/lookup\/doi\/10.1136\/jcp.2004.023721"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,4,27]]},"references-count":23,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2005,4,27]]},"published-print":{"date-parts":[[2005,5]]}},"alternative-id":["10.1136\/jcp.2004.023721"],"URL":"https:\/\/doi.org\/10.1136\/jcp.2004.023721","relation":{},"ISSN":["0021-9746","1472-4146"],"issn-type":[{"type":"print","value":"0021-9746"},{"type":"electronic","value":"1472-4146"}],"subject":[],"published":{"date-parts":[[2005,4,27]]}}}