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Extensive infiltration by pleomorphic tumour cells and erythrophagocytosis by tumour cells were seen on histological examination of the spleen. Immunohistochemical analysis and staining were carried out. This is the second reported case of malignant histiocytosis presenting with spontaneous splenic rupture.<\/jats:p>","DOI":"10.1136\/jcp.2005.027870","type":"journal-article","created":{"date-parts":[[2006,6,27]],"date-time":"2006-06-27T12:07:37Z","timestamp":1151410057000},"page":"770-772","source":"Crossref","is-referenced-by-count":19,"title":["Malignant histiocytosis: a case report of a rare tumour presenting with spontaneous splenic rupture"],"prefix":"10.1136","volume":"59","author":[{"given":"S E","family":"Low","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J S","family":"Stafford","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2006,6,27]]},"reference":[{"key":"2025120521390937000_59.7.770.1","unstructured":"Rappaport H. Histiocytosis. In: Atlas of tumour pathology: tumours of the haematopoietic system. Section 3, fascicle 8. 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