{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,21]],"date-time":"2025-11-21T18:40:42Z","timestamp":1763750442362,"version":"3.45.0"},"reference-count":11,"publisher":"BMJ","issue":"12","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Clin Pathol"],"published-print":{"date-parts":[[2006,12]]},"abstract":"<jats:p>The simultaneous manifestation of different lymphomas in the same patient or even in the same tissue, defined as composite lymphoma, is very rare. The exceptional case of a patient who, presented with simultaneous manifestation of three different lymphomas after 30 years of successful treatment of a nodal T cell lymphoma is reported here. The three lymphomas were: (1) primary cutaneous marginal zone B cell lymphoma (MZBL); (2) nodal Epstein\u2013Barr virus (EBV)-associated classic Hodgkin\u2019s lymphoma (cHL) of the B cell type; and (3) peripheral T cell lymphoma coexisting in the skin and cervical lymph node. Immunohistochemical and molecular analyses showed different clonal origins of EBV-negative cutaneous MZBL and EBV-positive B cell cHL and, in addition, the presence of the same clonal T cell population in the skin and lymph node. The simultaneous occurrence of three different, clonally unrelated lymphomas in one patient at the same time has not been reported yet.<\/jats:p>","DOI":"10.1136\/jcp.2005.030825","type":"journal-article","created":{"date-parts":[[2006,12,1]],"date-time":"2006-12-01T13:23:53Z","timestamp":1164979433000},"page":"1312-1315","source":"Crossref","is-referenced-by-count":27,"title":["Three coexisting lymphomas in one patient: genetically related or only a coincidence?"],"prefix":"10.1136","volume":"59","author":[{"given":"M","family":"Steinhoff","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C","family":"Assaf","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"I","family":"Anagnostopoulos","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C C","family":"Geilen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H","family":"Stein","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M","family":"Hummel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2006,12,1]]},"reference":[{"unstructured":"Custer RP. Proceedings of the second national cancer conference. Vol 1. New York: American Cancer Society, 1954:554\u00e2\u0080\u00937.","key":"2025112110365101000_59.12.1312.1"},{"doi-asserted-by":"publisher","key":"2025112110365101000_59.12.1312.2","DOI":"10.1002\/1097-0142(19820515)49:10<2112::AID-CNCR2820491024>3.0.CO;2-2"},{"doi-asserted-by":"publisher","key":"2025112110365101000_59.12.1312.3","DOI":"10.1136\/jcp.2003.011882"},{"key":"2025112110365101000_59.12.1312.4","first-page":"297","volume":"9","year":"1992","journal-title":"Sem Diagn Pathol"},{"key":"2025112110365101000_59.12.1312.5","doi-asserted-by":"crossref","first-page":"3804","DOI":"10.1200\/JCO.1999.17.12.3804","volume":"17","year":"1999","journal-title":"J Clin Oncol"},{"doi-asserted-by":"publisher","key":"2025112110365101000_59.12.1312.6","DOI":"10.1056\/NEJM199904223401604"},{"doi-asserted-by":"publisher","key":"2025112110365101000_59.12.1312.7","DOI":"10.1111\/j.1365-2559.2005.02046.x"},{"doi-asserted-by":"publisher","key":"2025112110365101000_59.12.1312.8","DOI":"10.1002\/(SICI)1097-0215(19970516)71:4<510::AID-IJC2>3.0.CO;2-X"},{"doi-asserted-by":"publisher","key":"2025112110365101000_59.12.1312.9","DOI":"10.1002\/1097-0142(19920501)69:9<2337::AID-CNCR2820690923>3.0.CO;2-K"},{"doi-asserted-by":"publisher","key":"2025112110365101000_59.12.1312.10","DOI":"10.1038\/sj.onc.1207843"},{"doi-asserted-by":"publisher","key":"2025112110365101000_59.12.1312.11","DOI":"10.1182\/blood.V98.1.194"}],"container-title":["Journal of Clinical Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/jcp.2005.030825","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,11,21]],"date-time":"2025-11-21T18:36:58Z","timestamp":1763750218000},"score":1,"resource":{"primary":{"URL":"https:\/\/jcp.bmj.com\/lookup\/doi\/10.1136\/jcp.2005.030825"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,12]]},"references-count":11,"journal-issue":{"issue":"12","published-online":{"date-parts":[[2006,12,1]]},"published-print":{"date-parts":[[2006,12]]}},"alternative-id":["10.1136\/jcp.2005.030825"],"URL":"https:\/\/doi.org\/10.1136\/jcp.2005.030825","relation":{},"ISSN":["0021-9746","1472-4146"],"issn-type":[{"type":"print","value":"0021-9746"},{"type":"electronic","value":"1472-4146"}],"subject":[],"published":{"date-parts":[[2006,12]]}}}