{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,6]],"date-time":"2025-12-06T08:15:24Z","timestamp":1765008924377,"version":"3.46.0"},"reference-count":23,"publisher":"BMJ","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Clin Pathol"],"published-print":{"date-parts":[[2008,6]]},"abstract":"<jats:sec>\n                    <jats:title>Aim:<\/jats:title>\n                    <jats:p>To evaluate the usefulness of vacuum assisted stereotactic guided mammotome biopsy in the diagnostic management of screen detected calcifications and to rationalise its use versus diagnostic excision.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>The first 100 mammotome biopsies preceded by a conventional needle core biopsy (NCB) were identified from the database of Leeds\/Wakefield Breast Screening Service. The histological diagnosis on NCB and mammotome were reviewed and compared with the surgical histological diagnosis if excision had been performed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>Using mammotome, diagnoses were changed in 74 of the 100 cases. In 66 cases a definitive diagnosis (B2 or B5) was obtained. The incidence of inadequate\/unsatisfactory (B1) biopsies was reduced from 36% to 9%. In 34 cases mammotome was not helpful in arriving at a definite diagnosis (B1\/B3\/B4). All cases diagnosed as malignant with mammotome were proven to have in situ or invasive malignancy on excision except for one case of ductal carcinoma in situ fully excised by mammotome. There was one false negative case of in-situ carcinoma with a prior benign (B2) mammotome diagnosis. Almost half the NCB uncertain (B3) cases required excision as the mammotome biopsies were also uncertain (B3). The majority were flat epithelial atypia and atypical intraductal proliferation.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>Mammotome biopsy is particularly useful for further assessment of an inadequate (B1) or suspicious (B4) NCB diagnosis. Diagnostic surgical excision remains the method of choice for managing atypical\/uncertain lesions (B3).<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1136\/jcp.2007.054130","type":"journal-article","created":{"date-parts":[[2008,3,6]],"date-time":"2008-03-06T20:45:05Z","timestamp":1204836305000},"page":"766-769","source":"Crossref","is-referenced-by-count":22,"title":["Vacuum assisted stereotactic guided mammotome biopsies in the management of screen detected microcalcifications: experience of a large breast screening centre"],"prefix":"10.1136","volume":"61","author":[{"given":"V","family":"Kumaroswamy","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J","family":"Liston","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A M","family":"Shaaban","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2008,3,6]]},"reference":[{"key":"2025120600125849000_61.6.766.1","doi-asserted-by":"crossref","first-page":"1109","DOI":"10.1016\/S0033-8389(22)00646-7","article-title":"Evaluation of breast microcalcifications.","volume":"33","author":"Monsees","year":"1995","journal-title":"Radiol Clin North Am"},{"key":"2025120600125849000_61.6.766.2","doi-asserted-by":"crossref","first-page":"631","DOI":"10.1148\/radiology.183.3.1584909","article-title":"Stereotaxic core biopsy of breast lesions.","volume":"183","author":"Dronkers","year":"1992","journal-title":"Radiology"},{"key":"2025120600125849000_61.6.766.3","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1148\/radiology.188.2.8327696","article-title":"Nonpalpable breast lesions: correlation of stereotaxic large-core needle biopsy and surgical biopsy results.","volume":"188","author":"Elvecrog","year":"1993","journal-title":"Radiology"},{"key":"2025120600125849000_61.6.766.4","first-page":"738","article-title":"Stereotactic breast biopsy: improved tissue harvesting with the mammotome.","volume":"62","author":"Burbank","year":"1996","journal-title":"Am Surg"},{"key":"2025120600125849000_61.6.766.5","doi-asserted-by":"crossref","first-page":"575","DOI":"10.1148\/radiology.204.2.9240556","article-title":"Stereotactic breast biopsy of clustered microcalcifications with a directional, vacuum-assisted device.","volume":"204","author":"Meyer","year":"1997","journal-title":"Radiology"},{"key":"2025120600125849000_61.6.766.6","doi-asserted-by":"publisher","DOI":"10.1093\/jjco\/hye112"},{"key":"2025120600125849000_61.6.766.7","first-page":"335","article-title":"Advantages and limits of percutaneous breast core biopsy with mammotome and stereotactic equipment in upright seated patient.","volume":"108","author":"Della Sala","year":"2004","journal-title":"Radiol Med (Torino)"},{"key":"2025120600125849000_61.6.766.8","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(20010101)91:1<173::AID-CNCR22>3.0.CO;2-9"},{"key":"2025120600125849000_61.6.766.9","unstructured":"NHS Cancer Screening Programmes and the Royal College of Pathologists . Pathology reporting of breast disease. Publication no 58. NHSBSP, 2005."},{"key":"2025120600125849000_61.6.766.10","doi-asserted-by":"crossref","first-page":"1503","DOI":"10.2214\/ajr.179.6.1791503","article-title":"Stereotactic 11-gauge vacuum-assisted breast biopsy: a validation study.","volume":"179","author":"Pfarl","year":"2002","journal-title":"AJR Am J Roentgenol"},{"key":"2025120600125849000_61.6.766.11","unstructured":"Wilson R Liston J , eds. Clinical guidelines for breast cancer screening and assessment, 2nd edn. NHSBSP Publication No 49. 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