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Many non-specialist diagnostic histopathologists may be unfamiliar with these obstetric advances, but they are an increasingly common indication for submission of placentas for histological examination. Since the aims of pathological examination of the placenta are to determine the pathological basis for the clinical findings and advance understanding of the pathophysiology of pregnancy complications, this review therefore provides an overview of the most common prenatal sonographic techniques and their clinical relevance to the diagnostic pathologist, primarily focusing on conditions with specific placental implications. These range from abnormalities of placental site and cord insertion, to obstetric complications such as antepartum haemorrhage, through sonographic placental parenchymal lesions such as subchorionic and intervillous thrombi, or chorioangiomata. In addition, the pathophysiological  basis of abnormal maternal and fetal maternal Doppler indices and intrauterine growth restriction are now described, being associated with decidual vasculopathy and villous changes associated with reduced intervillous blood flow respectively. Finally, rare but characteristic, sonographic appearances of villous cystic or hydropic change, may be associated with intrinsic developmental placental abnormalities such as hydatidiform mole and placental mesenchymal dysplasia, which require histological examination for their specific diagnosis.<\/jats:p>","DOI":"10.1136\/jcp.2008.055251","type":"journal-article","created":{"date-parts":[[2008,8,5]],"date-time":"2008-08-05T23:29:03Z","timestamp":1217978943000},"page":"1276-1284","source":"Crossref","is-referenced-by-count":64,"title":["Correlation of placental pathology with prenatal ultrasound findings"],"prefix":"10.1136","volume":"61","author":[{"given":"N J","family":"Sebire","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"W","family":"Sepulveda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2008,8,4]]},"reference":[{"key":"2025092501292360000_61.12.1276.1","doi-asserted-by":"crossref","first-page":"706","DOI":"10.5858\/2002-126-0706-DIPDOP","article-title":"Discrepancy in pathologic diagnosis of placental lesions.","volume":"126","author":"Sun","year":"2002","journal-title":"Arch Pathol Lab Med"},{"key":"2025092501292360000_61.12.1276.2","doi-asserted-by":"crossref","unstructured":"Fox H Sebire NJ . 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