{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,14]],"date-time":"2025-12-14T06:35:28Z","timestamp":1765694128959,"version":"3.48.0"},"reference-count":10,"publisher":"BMJ","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Clin Pathol"],"published-print":{"date-parts":[[2010,4]]},"abstract":"<jats:p>\n                    A 43-year-old man, admitted with a swollen right thigh, was diagnosed with a deep vein thrombosis. On day 6 he became septic. A CT scan demonstrated a right-sided hydronephrosis and a large retroperitoneal collection. Blood cultures and perinephric pus grew\n                    <jats:italic>Escherichia coli<\/jats:italic>\n                    resistant to amoxicillin only. On day 12 a vesicular rash appeared on the neck and herpes simplex virus 1 (HSV-1) grew on culture. On day 15 an upper leg collection was seen on CT scan. Thigh tissue specimens grew extended-spectrum \u03b2-lactamase (ESBL) producing\n                    <jats:italic>E coli<\/jats:italic>\n                    and HSV-1 was also detected by polymerase chain reaction in the tissue. On day 18 the patient died. This case illustrates an unusual presentation and complication of a perinephric abscess. In critically ill patients herpes simplex reactivation and emergence of multiresistant organisms may occur resulting in treatment failure.\n                  <\/jats:p>","DOI":"10.1136\/jcp.2009.071787","type":"journal-article","created":{"date-parts":[[2010,3,30]],"date-time":"2010-03-30T15:43:17Z","timestamp":1269963797000},"page":"365-366","source":"Crossref","is-referenced-by-count":2,"title":["Extensive perinephric abscess complicated by herpes simplex virus 1 reactivation"],"prefix":"10.1136","volume":"63","author":[{"given":"SA","family":"Alleyne","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"SS","family":"Bukhari","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M","family":"Fraser","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P","family":"Spiers","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2010,3,30]]},"reference":[{"key":"2025121322305608000_63.4.365.1","doi-asserted-by":"publisher","DOI":"10.1007\/BF02923976"},{"key":"2025121322305608000_63.4.365.2","doi-asserted-by":"publisher","DOI":"10.1007\/s00268-006-0162-x"},{"key":"2025121322305608000_63.4.365.3","unstructured":"Health Protection Agency. Voluntary reports of bacteraemia due to Escherichia coli made to the HPA between 2003 and 2007 from participating laboratories in England, Wales and Northern Ireland. 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