{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,24]],"date-time":"2026-06-24T04:58:29Z","timestamp":1782277109957,"version":"3.54.5"},"reference-count":48,"publisher":"BMJ","issue":"12","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Clin Pathol"],"accepted":{"date-parts":[[2010,8,31]]},"published-print":{"date-parts":[[2010,12]]},"abstract":"<jats:sec>\n                    <jats:title>Aims<\/jats:title>\n                    <jats:p>To characterise the predominant species of bacterial populations associated with duodenal biopsies of paediatric patients with active and treated coeliac disease.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      20 biopsy specimens from patients with active coeliac disease, 12 from patients with treated coeliac disease, and eight from age-matched controls were evaluated for comparative purposes.\n                      <jats:italic>Bacteroides<\/jats:italic>\n                      ,\n                      <jats:italic>Bifidobacterium<\/jats:italic>\n                      and lactic acid bacteria (LAB) populations were analysed by PCR-denaturing gradient gel electrophoresis using group-specific primers.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      <jats:italic>Bacteroides<\/jats:italic>\n                      diversity was higher in biopsy specimens from controls than in those from patients with active and treated coeliac disease.\n                      <jats:italic>Bacteroides distasonis<\/jats:italic>\n                      ,\n                      <jats:italic>Bacteroides fragilis\/Bacteroides thetaiotaomicron<\/jats:italic>\n                      ,\n                      <jats:italic>Bacteroides uniformis<\/jats:italic>\n                      and\n                      <jats:italic>Bacteroides ovatus<\/jats:italic>\n                      were more abundant in controls than in patients with coeliac disease (p&lt;0.05).\n                      <jats:italic>Bacteroides vulgatus<\/jats:italic>\n                      was more frequently detected in controls than in patients with treated coeliac disease (p&lt;0.01).\n                      <jats:italic>Bacteroides dorei<\/jats:italic>\n                      was more common in patients with active coeliac disease than in those with treated coeliac disease and control children (p&lt;0.01).\n                      <jats:italic>Bifidobacterium<\/jats:italic>\n                      diversity was higher in patients with coeliac disease than in controls.\n                      <jats:italic>Bifidobacterium adolescentis<\/jats:italic>\n                      and\n                      <jats:italic>Bifidobacterium animalis<\/jats:italic>\n                      subsp\n                      <jats:italic>lactis<\/jats:italic>\n                      were more prevalent in patients with active coeliac disease than in patients with treated coeliac disease and control children. A higher LAB diversity was found in patients with treated coeliac disease and controls than in patients with active coeliac disease.\n                      <jats:italic>Weissella<\/jats:italic>\n                      spp and\n                      <jats:italic>Lactobacillus fermentum<\/jats:italic>\n                      were more frequently detected in patients with treated coeliac disease than in controls and patients with active coeliac disease.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>\n                      <jats:italic>Bacteroides<\/jats:italic>\n                      ,\n                      <jats:italic>Bifidobacterium<\/jats:italic>\n                      and LAB populations in the duodenum of Spanish children with typical coeliac disease (active and treated) and controls differ in diversity and species composition; this could contribute to features of the disease.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1136\/jcp.2010.076950","type":"journal-article","created":{"date-parts":[[2010,10,23]],"date-time":"2010-10-23T20:24:54Z","timestamp":1287865494000},"page":"1105-1111","source":"Crossref","is-referenced-by-count":86,"title":["Intestinal\n                    <i>Bacteroides<\/i>\n                    species associated with coeliac 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