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In the breast, its bland histological appearances can lead to a benign diagnosis. Clues to the correct conclusion include finding tumour cells with more cytological atypia, the presence of cytoplasmic vacuoles and secretions, coexistence with more traditional invasive lobular carcinoma patterns and\/or lobular neoplasia, and the use of immuohistochemistry to confirm their epithelial nature. Close clinicoradiological correlation and awareness of histological mimics are needed to achieve an accurate diagnosis of this enigmatic condition that should be appropriately subsumed within the invasive lobular histological subtype.<\/jats:p>","DOI":"10.1136\/jcp.2011.088930","type":"journal-article","created":{"date-parts":[[2011,3,13]],"date-time":"2011-03-13T19:28:02Z","timestamp":1300044482000},"page":"654-659","source":"Crossref","is-referenced-by-count":35,"title":["Histiocytoid breast carcinoma: an enigmatic lobular entity"],"prefix":"10.1136","volume":"64","author":[{"given":"Puay Hoon","family":"Tan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Oi","family":"Harada","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aye Aye","family":"Thike","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gary Man-Kit","family":"Tse","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2011,3,12]]},"reference":[{"key":"2025092504221422000_64.8.654.1","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(197304)31:4<793::AID-CNCR2820310406>3.0.CO;2-A"},{"key":"2025092504221422000_64.8.654.2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2559.1989.tb02187.x"},{"key":"2025092504221422000_64.8.654.3","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1016\/S0046-8177(84)80053-2","article-title":"Apocrine differentiation in lobular carcinoma of the breast: a morphologic, immunologic, and ultrastructural study","volume":"15","author":"Eusebi","year":"1984","journal-title":"Hum Pathol"},{"key":"2025092504221422000_64.8.654.4","doi-asserted-by":"publisher","DOI":"10.1097\/00000478-199505000-00007"},{"key":"2025092504221422000_64.8.654.5","doi-asserted-by":"publisher","DOI":"10.1016\/0046-8177(92)90321-S"},{"key":"2025092504221422000_64.8.654.6","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-1827.2005.01836.x"},{"key":"2025092504221422000_64.8.654.7","first-page":"249","article-title":"Histiocytoid breast carcinoma: a case report of an uncommon histologic variant of lobular carcinoma","volume":"23","author":"Kostopoulos","year":"2003","journal-title":"Ann Pathol"},{"key":"2025092504221422000_64.8.654.8","doi-asserted-by":"publisher","DOI":"10.1002\/dc.10103"},{"key":"2025092504221422000_64.8.654.9","doi-asserted-by":"crossref","first-page":"1626","DOI":"10.5858\/2003-127-1626-PQCAYW","article-title":"Pathologic quiz case: a 93-year-old woman with an enlarged and tender left breast. 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