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In the second case idiopathic diffuse interstitial pulmonary fibrosis was complicated by large cell anaplastic carcinoma of the lung.<\/jats:p><jats:p>It is suggested that in both cases the development of carcinoma of the lung was a complication of the epithelial hyperplasia and scarring that occurs in diffuse interstitial pulmonary fibrosis.<\/jats:p><jats:p>It is also suggested that carcinoma found in the main bronchi in patients with diffuse interstitial pulmonary fibrosis should not be regarded as coincidental unless careful search has excluded a carcinomatous change in the periphery of the scarred lungs.<\/jats:p>","DOI":"10.1136\/jcp.21.4.486","type":"journal-article","created":{"date-parts":[[2007,6,9]],"date-time":"2007-06-09T04:50:46Z","timestamp":1181364646000},"page":"486-491","source":"Crossref","is-referenced-by-count":30,"title":["Carcinoma of the lung and diffuse interstitial pulmonary fibrosis"],"prefix":"10.1136","volume":"21","author":[{"given":"B.","family":"Fox","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R. 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