{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,26]],"date-time":"2025-09-26T00:17:40Z","timestamp":1758845860958,"version":"3.44.0"},"reference-count":19,"publisher":"BMJ","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Clin Pathol"],"published-print":{"date-parts":[[1969,11]]},"abstract":"<jats:p>Fine needle aspiration biopsy smears from 19 patients with porphyria cutanea tarda were studied by fluorescence microscopy. Fluorescence was arbitrarily graded from 0 to 4. All patients\u2014those with clinically manifest as well as those with latent disease\u2014showed bright red fluorescence of porphyrin type in the liver cells, though in latent cases the fluorescence commonly was of a low grade. In patients with manifest disease fluorescence of grade 3 or 4 was present.<\/jats:p>\n               <jats:p>In patients with fluorescence of grades 1 or 2 the uroporphyrin excretion in urine was normal or slightly increased. At higher grades all levels of porphyrin excretion were encountered.<\/jats:p>\n               <jats:p>Of 22 control subjects, only one showed hepatic fluorescence of a porphyrin character. The control patient with a positive finding was found to have definitely increased urinary uroporphyrin excretion and probably has latent porphyria cutanea tarda.<\/jats:p>\n               <jats:p>The procedure described should be useful as a screening test for hepatic cutaneous porphyria.<\/jats:p>","DOI":"10.1136\/jcp.22.6.704","type":"journal-article","created":{"date-parts":[[2007,6,9]],"date-time":"2007-06-09T00:50:46Z","timestamp":1181350246000},"page":"704-709","source":"Crossref","is-referenced-by-count":18,"title":["Hepatic fluorescence in porphyria cutanea tarda studied in fine needle aspiration biopsy smears"],"prefix":"10.1136","volume":"22","author":[{"given":"Ove","family":"Lundvall","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lennart","family":"Enerb\u00e4ck","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[1969,11,1]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"318","DOI":"10.3109\/00365515109060622","volume":"3","author":"Askevold, R.","year":"1951","unstructured":"Askevold, R. (1951). Scand. J. clin. Lab. Invest., 3, 318.","journal-title":"Scand. J. clin. Lab. Invest"},{"key":"ref_2","first-page":"597","volume":"5","author":"Braun, A.; Berman, J.","year":"1959","unstructured":"Braun, A., and Berman, J. (1959). Acta Univ. Carol. Med. (Praha), 5, 597.","journal-title":"Acta Univ. Carol. Med. (Praha)"},{"key":"ref_3","first-page":"193","volume":"32","author":"EnerbEck, L.; Lundvall, 0","year":"1969","unstructured":"EnerbEck, L., and Lundvall, 0. (1969). To be published. Franz6n, S., Giertz, G., and Zajicek, J. (1960). Brit. J. Urol., 32, 193.","journal-title":"Brit. J. Urol"},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1002\/aja.1000710103","volume":"71","author":"Grafflin, A.L.","year":"1942","unstructured":"Grafflin, A. L. (1942). Amer. J. Anat., 71, 43.","journal-title":"Amer. J. Anat"},{"key":"ref_5","first-page":"456","volume":"41","author":"Hickman, R.; Saunders, S.J.; Eales, L.","year":"1967","unstructured":"Hickman, R., Saunders, S. J., and Eales, L. (1967). S. Afr. med. J., 41, 456.","journal-title":"S. Afr. med. J"},{"key":"ref_6","first-page":"1","volume":"27","author":"Holti, G.; Rimington, C.; Tate, B.C.; Thomas, G.","year":"1958","unstructured":"Holti, G., Rimington, C., Tate, B. C., and Thomas, G. (1958). Quart. J. Med., 27, 1.","journal-title":"Quart. J. Med"},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1007\/BF01483617","volume":"38","author":"Ippen, H.","year":"1960","unstructured":"Ippen, H. (1960). Klin. Wschr., 38, 89.","journal-title":"Klin. Wschr"},{"key":"ref_8","first-page":"373","volume":"30","author":"Lamont, N.M.; Hathorn, M.; Joubert, S.M.","year":"1961","unstructured":"Lamont, N. M., Hathorn, M., and Joubert, S. M. (1961). Quart. J. Med., 30, 373.","journal-title":"Quart. J. Med"},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1111\/j.0954-6820.1968.tb02443.x","volume":"184","author":"Lundvall, O.; Weinfeld, A.","year":"1968","unstructured":"Lundvall, O., and Weinfeld, A. (1968). Acta med. scand., 184, 191.","journal-title":"Acta med. scand"},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1016\/S0021-9258(18)65809-0","volume":"219","author":"Mauzerall, D.; Granick, S.","year":"1956","unstructured":"Mauzerall, D., and Granick, S. (1956). J. biol. Chem., 219, 435.","journal-title":"J. biol. Chem"},{"key":"ref_11","first-page":"738","volume":"219","author":"Niebauer, C.","year":"1964","unstructured":"Niebauer, C. (1964). Arch. klin. exp. Derm., 219, 738.","journal-title":"Arch. klin. exp. Derm"},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"209","DOI":"10.3109\/00365515009049872","volume":"2","author":"Rimington, C.; Sveinsson, S.L.","year":"1950","unstructured":"Rimington, C., and Sveinsson, S. L. (1950). Scand. J. clin. Lab. Invest., 2, 209.","journal-title":"Scand. J. clin. Lab. Invest"},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1001\/archinte.1954.00240260001001","volume":"93","author":"Schmid, R.; Schwartz, S.; Watson, C.J.","year":"1954","unstructured":"Schmid, R., Schwartz, S., and Watson, C. J. (1954). Arch. intern. Med., 93, 167.","journal-title":"Arch. intern. Med"},{"key":"ref_14","article-title":"Fine-Needle Aspiration Biopsy","author":"Soderstrom, N.","year":"1966","unstructured":"Soderstrom, N. (1966). Fine-Needle Aspiration Biopsy. Almqvist and Wiksell, Stockholm."},{"key":"ref_15","first-page":"190","volume":"9","author":"Uys, C.J.; Eales, L.","year":"1963","unstructured":"Uys, C. J., and Eales, L. (1963). S. Afr. J. Lab. clin. Med., 9, 190.","journal-title":"Lab. clin. Med"},{"key":"ref_16","first-page":"831","volume":"37","author":"Watson, C.J.; Pimenta de Mello, R.; Schwartz, S.; Hawkinson, V.E.; Bossenmaier, I.","year":"1951","unstructured":"Watson, C. J., Pimenta de Mello, R., Schwartz, S., Hawkinson, V. E., and Bossenmaier, I. (1951). J. Lab. clin. Med., 37, 831.","journal-title":"J. Lab. clin. Med"},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"193","DOI":"10.3109\/00365515509134507","volume":"7","author":"With, T.K.","year":"1955","unstructured":"With, T. K. (1955). Scand. J. clin. Lab. Invest., 7, 193.","journal-title":"Scand. J. clin. Lab. Invest"},{"key":"ref_18","unstructured":"The November 1969 Issue","article-title":"The November 1969 Issue"},{"key":"ref_19","unstructured":"THE NOVEMBER 1969 ISSUE CONTAINS THE FOLLOWING PAPERS","article-title":"THE NOVEMBER 1969 ISSUE CONTAINS THE FOLLOWING PAPERS"}],"container-title":["Journal of Clinical Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/jcp.22.6.704","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,9,25]],"date-time":"2025-09-25T12:02:26Z","timestamp":1758801746000},"score":1,"resource":{"primary":{"URL":"https:\/\/jcp.bmj.com\/lookup\/doi\/10.1136\/jcp.22.6.704"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1969,11]]},"references-count":19,"journal-issue":{"issue":"6","published-online":{"date-parts":[[1969,11,1]]},"published-print":{"date-parts":[[1969,11]]}},"alternative-id":["10.1136\/jcp.22.6.704"],"URL":"https:\/\/doi.org\/10.1136\/jcp.22.6.704","relation":{},"ISSN":["0021-9746","1472-4146"],"issn-type":[{"type":"print","value":"0021-9746"},{"type":"electronic","value":"1472-4146"}],"subject":[],"published":{"date-parts":[[1969,11]]}}}