{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T04:53:08Z","timestamp":1761540788510,"version":"3.44.0"},"reference-count":15,"publisher":"BMJ","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Clin Pathol"],"published-print":{"date-parts":[[1970,4]]},"abstract":"<jats:p>A modification of Salzman's method has been used in an attempt to provide an assay <jats:italic>in vitro<\/jats:italic> for the von Willebrand factor. Platelet adhesiveness was increased in von Willebrand's disease by previously coating the beads with normal or haemophilic plasma or cryoprecipitate, whereas von Willebrand plasma had no corrective effect. Antihaemophilic factor (AHF) concentrates were studied in the same way and results compared with experiments <jats:italic>in vivo.<\/jats:italic>\n               <\/jats:p>","DOI":"10.1136\/jcp.23.3.228","type":"journal-article","created":{"date-parts":[[2007,6,9]],"date-time":"2007-06-09T00:50:46Z","timestamp":1181350246000},"page":"228-231","source":"Crossref","is-referenced-by-count":26,"title":["Von Willebrand factor and platelet adhesiveness"],"prefix":"10.1136","volume":"23","author":[{"given":"Dominique","family":"Meyer","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marie-Jos\u00e9","family":"Larrieu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[1970,4,1]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1111\/j.1365-2141.1963.tb05457.x","article-title":"Transfusion studies in von Willebrand's disease: effect on bleeding time and factor VIII","volume":"9","author":"Cornu, P.; Larrieu, M.J.; Caen, J.P.; Bernard, J.","year":"1963","unstructured":"Cornu, P., Larrieu, M. J., Caen, J. P., and Bernard, J. (1963). Transfusion studies in von Willebrand's disease: effect on bleeding time and factor VIII. Brit. J. Haemat., 9, 189-202.","journal-title":"Brit. J. Haemat"},{"key":"ref_2","first-page":"23","article-title":"The potent antihemophilic globulin concentrate derived from a cold insoluble fraction of human plasma","volume":"67","author":"Hershgold, E.J.; Pool, J.G.; Pappenhagen, A.R.","year":"1966","unstructured":"Hershgold, E. J., Pool, J. G., and Pappenhagen, A. R. (1966). The potent antihemophilic globulin concentrate derived from a cold insoluble fraction of human plasma. J. Lab. clin. Med., 67, 23-32.","journal-title":"J. Lab. clin. Med"},{"key":"ref_3","first-page":"377","article-title":"Purification of antihemophilic factor (AHF) for clinical and experimental use","volume":"Suppl.","author":"Johnson, A.J.; Newman, J.; Howell, M.B.; Puszkin, S.","year":"1967","unstructured":"Johnson, A. J., Newman, J., Howell, M. B., and Puszkin, S. (1967). Purification of antihemophilic factor (AHF) for clinical and experimental use. Thrombos. Diathes. haemorrh. (Stuttg.), Suppl. 377-381.","journal-title":"Thrombos. Diathes. haemorrh. (Stuttg.)"},{"key":"ref_4","first-page":"354","article-title":"Congenital bleeding disorders with bleeding, time and normal platelet count","volume":"45","author":"Larrieu, M.J.; Caen, J.P.; Meyer, D.O.; Vainer, H.; Sultan, Y.; Bernard, J.","year":"1968","unstructured":"Larrieu, M. J., Caen, J. P., Meyer, D. O., Vainer, H., Sultan, Y., and Bernard, J. (1968). Congenital bleeding disorders with bleeding, time and normal platelet count. II. von Willebrand's disease. Amer. J. Med., 45, 354-372.","journal-title":"II. von Willebrand's disease. Amer. J. Med"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1016\/S0021-9258(19)52451-6","article-title":"Protein measurement with the Folin phenol reagent","volume":"193","year":"1951","unstructured":"Lowry, 0. H., Rosebrough, N. J., Farr, A. L., and Randall, R. J. (1951). Protein measurement with the Folin phenol reagent. J. biol. Chem., 193, 265-275.","journal-title":"J. biol. Chem"},{"key":"ref_6","first-page":"736","article-title":"L'analyse des fonctions plaquettaires: mesure de l'adhesivit6 des plaquettes au verre sur sang total (methode de Salzman)","volume":"12","author":"Meyer, D.; Larrieu, M.J.","year":"1967","unstructured":"Meyer, D., and Larrieu, M. J. (1967). L'analyse des fonctions plaquettaires: mesure de l'adhesivit6 des plaquettes au verre sur sang total (methode de Salzman). Rev. franC. ttud. clin. biol., 12, 736-739."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1136\/jcp.20.2.190","article-title":"Biological findings in von Willebrand's pedigrees: implications for inheritance","volume":"20","author":"Meyer, D.; Larrieu, M.J.","year":"1967","unstructured":"Meyer, D., and Larrieu, M. J. (1967b). Biological findings in von Willebrand's pedigrees: implications for inheritance. J. clin. Path. 20, 190-194.","journal-title":"J. clin. Path"},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1111\/j.0954-6820.1957.tb00123.x","article-title":"von Willebrand's disease and its correction with human plasma fraction 1-0","volume":"159","author":"Nilsson, I.M.; Blomback, M.; Jorpes, E.; Blomback, B.; Johansson, S.A.","year":"1957","unstructured":"Nilsson, I. M., Blomback, M., Jorpes, E., Blomback, B., and Johansson, S. A. (1957). von Willebrand's disease and its correction with human plasma fraction 1-0. Acta med. scand., 159, 179-188.","journal-title":"Acta med. scand"},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1136\/jcp.20.1.56","article-title":"Some interactions between human platelets and glass: von Willebrand's disease compared with normal","volume":"20","author":"O'Brien, J.R.; Heywood, J.B.","year":"1967","unstructured":"O'Brien, J. R., and Heywood, J. B. (1967). Some interactions between human platelets and glass: von Willebrand's disease compared with normal. J. clin Path., 20, 56-64.","journal-title":"J. clin Path"},{"key":"ref_10","first-page":"686","article-title":"The effect of plasma proteins on the interaction of platelets with glass surfaces","volume":"73","author":"Packham, M.A.; Evans, G.; Glynn, M.F.; Mustard, J.F.","year":"1969","unstructured":"Packham, M. A., Evans, G., Glynn, M. F., and Mustard, J. F. (1969). The effect of plasma proteins on the interaction of platelets with glass surfaces. J. Lab. clin.Med., 73, 686-697.","journal-title":"J. Lab. clin. Med"},{"key":"ref_11","first-page":"724735","article-title":"Measurement of platelet adhesiveness: a simple in vitro technique demonstrating an abnormality in von Willebrand's disease","volume":"62","author":"Salzman, E.W.","year":"1963","unstructured":"Salzman, E. W. (1963). 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(1965). von Willebrand's disease: use of a platelet-adhesiveness test in diagnosis and family investigation. New Engi. J. Med., 273, 171-181.","journal-title":"New Engi. J. Med"},{"key":"ref_14","volume":"97","author":"Vigliano, E.; Horowitz, H.","year":"1966","unstructured":"Vigliano, E., and Horowitz, H. (1966). Information Exchange Group, 97.","journal-title":"Information Exchange Group"},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"601","DOI":"10.1038\/197601a0","article-title":"In vitro abnurmality of the blood in von Willebrand's disease correctable by normal plasma","author":"Zucker, M.B.","year":"1963","unstructured":"Zucker, M. B. (1963). In vitro abnurmality of the blood in von Willebrand's disease correctable by normal plasma. 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