{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,21]],"date-time":"2025-11-21T18:30:07Z","timestamp":1763749807207,"version":"3.45.0"},"reference-count":26,"publisher":"BMJ","issue":"7","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Clin Pathol"],"published-print":{"date-parts":[[1970,10]]},"abstract":"<jats:p>\n                    An assessment of vitamin B\n                    <jats:sub>12<\/jats:sub>\n                    absorption in neurological patients has been made by both serum and urine counting of\n                    <jats:sup>57<\/jats:sup>\n                    Co cyanocobalamin during the conventional Schilling test. Although patients with pernicious anaemia, some with subacute combined degeneration of the cord, have been studied, emphasis in the discussion is placed on the significantly increased excretion of the radioactive vitamin in a group of patients with pituitary insufficiency. Results are also given for epileptic patients who have developed folate deficiency (as assessed by serum folate levels) coincidental with anticonvulsant therapy, as well as for some patients who have had neurological symptoms or signs following partial gastrectomy operations.\n                  <\/jats:p>","DOI":"10.1136\/jcp.23.7.563","type":"journal-article","created":{"date-parts":[[2007,6,9]],"date-time":"2007-06-09T00:50:46Z","timestamp":1181350246000},"page":"563-568","source":"Crossref","is-referenced-by-count":1,"title":["Vitamin B\n                    <sub>12<\/sub>\n                    absorption in some neurological and neuroendocrine disorders"],"prefix":"10.1136","volume":"23","author":[{"given":"D.","family":"Donaldson","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P. T.","family":"Lascelles","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[1970,10,1]]},"reference":[{"issue":"421 431","key":"ref_1","article-title":"Addisonian pernicious anaemia and intrinsic factor antibodies in thyroid disorders","volume":"35","author":"Ardeman, S.; Chanarin, I.; Krafchik, B.; Singer, W.","year":"1966","unstructured":"Ardeman, S., Chanarin, I., Krafchik, B., and Singer, W. (1966). Addisonian pernicious anaemia and intrinsic factor antibodies in thyroid disorders. Quart. J. Med., 35, 421 431.","journal-title":"Quart. J. Med"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1111\/j.0954-6820.1952.tb15659.x","article-title":"Addison's disease: familial incidence and occurrence in association with pernicious anaemia","volume":"144","author":"Berlin, R.","year":"1952","unstructured":"Berlin, R. (1952). Addison's disease: familial incidence and occurrence in association with pernicious anaemia. Acta med. scand., 144, 1-6.","journal-title":"Acta med. scand"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"1246","DOI":"10.7326\/0003-4819-64-6-1246","article-title":"Coexistent pernicious anaemia and malabsorption in four patients (including one whose malabsorption disappeared with vitamin B,, therapy)","volume":"64","author":"Brody, E.A.; Estren, S.; Herbert, V.","year":"1966","unstructured":"Brody, E. A., Estren, S., and Herbert, V. (1966). Coexistent pernicious anaemia and malabsorption in four patients (including one whose malabsorption disappeared with vitamin B,, therapy). Ann. intern. Med., 64, 1246-1251.","journal-title":"Ann. intern. Med"},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1056\/NEJM196402132700703","article-title":"Absorption and disposition of D-xylose in thyrotoxicosis and myxoedema","volume":"270","author":"Broitman, S.A.; Bondy, D.C.; Yachnin, I.; Hoskins, L.C.; Ingbar, S.; Zamcheck, N.","year":"1964","unstructured":"Broitman, S. A., Bondy, D. C., Yachnin, I., Hoskins, L. C., Ingbar, S., and Zamcheck, N. (1964). Absorption and disposition of D-xylose in thyrotoxicosis and myxoedema. New Engi. J. Med., 270, 333-337.","journal-title":"New Engi. J. Med"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"1201","DOI":"10.7326\/0003-4819-67-6-1201","article-title":"Correctable intestinal defect of vitamin B,, absorption in pernicious anaemia","volume":"67","author":"Carmel, R.; Herbert, V.","year":"1967","unstructured":"Carmel, R., and Herbert, V. (1967). Correctable intestinal defect of vitamin B,, absorption in pernicious anaemia. Ann. intern. Med., 67, 1201-1207.","journal-title":"Ann. intern. Med"},{"key":"ref_6","first-page":"574577","article-title":"Effect of food on absorption of radioactive vitamin B","volume":"1","author":"D_.ller, D.J.; Germar, H.; Witts, L.J.","year":"1961","unstructured":"D_.ller, D. J., Germar, H., and Witts, L. J. (1961). Effect of food on absorption of radioactive vitamin B,,. Lancet, 1, 574577.","journal-title":"Lancet"},{"key":"ref_7","first-page":"588","article-title":"An assessment of serum 57Co cyanocobalamin as an index of vitamin B,, absorption","volume":"23","author":"Donaldson, D.; Blight, B.J.N.; Lascelles, P.T.","year":"1970","unstructured":"Donaldson, D., Blight, B. J. N., and Lascelles, P. T. (1970). An assessment of serum 57Co cyanocobalamin as an index of vitamin B,, absorption. J. clin. Path., 23, 588-562","journal-title":"J. clin. Path"},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"553","DOI":"10.1056\/NEJM196709142771101","article-title":"Mucosa ofthe smali intestine in pernicious anaemia","volume":"277","author":"Foroozan, P.; Trier, J.S.","year":"1967","unstructured":"Foroozan, P., and Trier, J. S. (1967). Mucosa ofthe smali intestine in pernicious anaemia. New Engi. J. Med., 277, 553-559.","journal-title":"New Engi. J. Med"},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1111\/j.0954-6820.1958.tb01752.x","article-title":"Thyroid function and pernicious anaemia. Comments on some typical cases","volume":"162","author":"Forssell, J.; Halunen, P.I.","year":"1958","unstructured":"Forssell, J., and Halunen, P. I. (1958). Thyroid function and pernicious anaemia. Comments on some typical cases. 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Endocrinology, 80, 623-628.","journal-title":"Endocrinology"},{"key":"ref_16","first-page":"567","volume":"15","author":"Okuda, K.; Steelman, S.; Chow, B.F.","year":"1956","unstructured":"Okuda, K., Steelman, S., and Chow, B. F. (1956). Absorption of vitamin B,, 15, 567.","journal-title":"Absorption of vitamin B"},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1111\/j.1528-1157.1966.tb03806.x","article-title":"Anticonvulsant therapy, folic acid and vitamin B,, metabolism and mental symptoms","volume":"7","author":"Reynolds, E.H.; Chanarin, I.; Milner, G.; Matthews, D.M.","year":"1966","unstructured":"Reynolds, E. H., Chanarin, I., Milner, G., and Matthews, D. M. (1966). Anticonvulsant therapy, folic acid and vitamin B,, metabolism and mental symptoms. 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R., and Wilson, G. M. (1962). Deficiency of vitamin"},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"752","DOI":"10.1111\/j.1365-2141.1967.tb08841.x","article-title":"Absorption of vitamin B,, in patients with anaemia after Polya partial gastrectomy","volume":"13","author":"Turnbull, A.L.","year":"1967","unstructured":"Turnbull, A. L. (1967). Absorption of vitamin B,, in patients with anaemia after Polya partial gastrectomy. Brit. J. Haemat., 13, 752-763.","journal-title":"Brit. J. Haemat"},{"key":"ref_22","article-title":"Inter-relationships between folic acid, vitamin B,2 and ascorbic acid in the megaloblastic anaemias","author":"Vilter, R.W.","year":"1964","unstructured":"Vilter, R. W. (1964). 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Studies on the folic acid activity of human serum. J. clin. Path., 14, 335-344.","journal-title":"J. clin. Path"},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1111\/j.1365-2141.1963.tb06556.x","article-title":"Observations on the metabolism of folic acid in p_rnicious anaemia","volume":"9","author":"Waters, A.H.; Mollin, D.L.","year":"1963","unstructured":"Waters, A. H., and Mollin, D. L. (1963). Observations on the metabolism of folic acid in p_rnicious anaemia. Brit. J. Haemat., 9, 319-327.","journal-title":"Brit. J. Haemat"},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"229","DOI":"10.3181\/00379727-96-23438","article-title":"Vitamin B,, in thyrotoxicosis and myxoedema","volume":"96","author":"Ziffer, H.; Gutman, A.; Pasher, I.; Sobotka, H.; Baker, H.","year":"1957","unstructured":"Ziffer, H., Gutman, A., Pasher, I., Sobotka, H., and Baker, H. (1957). Vitamin B,, in thyrotoxicosis and myxoedema. Proc. Soc. exp. Biol. (N. Y.), 96, 229-230.","journal-title":"Proc. Soc. exp. Biol. (N. Y.)"}],"container-title":["Journal of Clinical Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/jcp.23.7.563","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,11,21]],"date-time":"2025-11-21T18:26:21Z","timestamp":1763749581000},"score":1,"resource":{"primary":{"URL":"https:\/\/jcp.bmj.com\/lookup\/doi\/10.1136\/jcp.23.7.563"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1970,10]]},"references-count":26,"journal-issue":{"issue":"7","published-online":{"date-parts":[[1970,10,1]]},"published-print":{"date-parts":[[1970,10]]}},"alternative-id":["10.1136\/jcp.23.7.563"],"URL":"https:\/\/doi.org\/10.1136\/jcp.23.7.563","relation":{},"ISSN":["0021-9746","1472-4146"],"issn-type":[{"type":"print","value":"0021-9746"},{"type":"electronic","value":"1472-4146"}],"subject":[],"published":{"date-parts":[[1970,10]]}}}