{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,30]],"date-time":"2025-10-30T06:55:50Z","timestamp":1761807350767},"reference-count":40,"publisher":"BMJ","issue":"8","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Clin Pathol"],"published-print":{"date-parts":[[1970,11]]},"abstract":"<jats:p>The salient pathological findings in 40 patients with idiopathic retroperitoneal fibrosis are summarized. The findings tend to confirm previous suggestions that this chronic inflammatory disease is potentially widespread, predominantly peri-aortic, associated with systemic disturbances, and of some fundamental interest. The name `systemic idiopathic fibrosis' is suggested for the disease complex. The study suggests that damage to the wall of the aorta and its large branches might be the cause.<\/jats:p>","DOI":"10.1136\/jcp.23.8.681","type":"journal-article","created":{"date-parts":[[2007,6,9]],"date-time":"2007-06-09T04:50:46Z","timestamp":1181364646000},"page":"681-689","source":"Crossref","is-referenced-by-count":160,"title":["The pathology of idiopathic retroperitoneal fibrosis"],"prefix":"10.1136","volume":"23","author":[{"given":"M. J.","family":"Mitchinson","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[1970,11,1]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1002\/path.1700940109","article-title":"Connective tissue reactions to implantation of purified sterol, sterol esters, phosphoglycerides, glycerides and free fatty acids","volume":"94","author":"Abdulla, Y.H.; Adams, C.W.M.; Morgan, R.S.","year":"1967","unstructured":"Abdulla, Y. H., Adams, C. W. M., and Morgan, R. S. (1967). Connective tissue reactions to implantation of purified sterol, sterol esters, phosphoglycerides, glycerides and free fatty acids. J. Path. Bact., 94, 63-71.","journal-title":"J. Path. Bact"},{"key":"ref_2","first-page":"183","article-title":"Idiopathic retroperitoneal fibrosis with protein-losing enteropathy and duodenal obstruction successfully treated with corticosteroids","volume":"1","author":"Chew, C.K.; Jarzylo, S.V.; Valberg, L.S.","year":"1966","unstructured":"Chew, C. K., Jarzylo, S. V., and Valberg, L. S. (1966). Idiopathic retroperitoneal fibrosis with protein-losing enteropathy and duodenal obstruction successfully treated with corticosteroids. Canad. med. Ass. J., 95, 1 183-1188.","journal-title":"Canad. med. Ass. J., 95"},{"key":"ref_3","first-page":"812","article-title":"Bilateral ureteral obstruction due to chronic inflammation of the fascia around the ureters","volume":"72","author":"Chisholm, E.R.; Hutch, J.A.; Bolomey, A.A.","year":"1954","unstructured":"Chisholm, E. R., Hutch, J. A., and Bolomey, A. A. (1954). Bilateral ureteral obstruction due to chronic inflammation of the fascia around the ureters. J. Urol. (Baltimore), 72, 812-816.","journal-title":"J. Urol. (Baltimore)"},{"key":"ref_4","first-page":"299","article-title":"Bilateral ureteral obstruction","volume":"188","author":"Clouse, M.E.","year":"1964","unstructured":"Clouse, M. E. (1964). Bilateral ureteral obstruction. J. Anmer. med. Ass., 188, 299-301.","journal-title":"J. Anmer. med. Ass"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"884","DOI":"10.7326\/0003-4819-66-5-884","article-title":"Familial multifocal fibrosclerosis","volume":"66","author":"Comings, D.E.; Skubi, K.B.; Van Eyes, J.; Motulsky, A.G.","year":"1967","unstructured":"Comings, D. E., Skubi, K. B., Van Eyes, J., and Motulsky, A. G. (1967). Familial multifocal fibrosclerosis. Ann. intern. Med., 66, 884-892.","journal-title":"Ann. intern. Med"},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"808","DOI":"10.1001\/jama.1966.03110210058021","article-title":"Aortic obstruction associated with methysergide maleate therapy for headaches","volume":"198","author":"Conley, J.E.; Boulanger, W.J.; Mendeloff, G.L.","year":"1966","unstructured":"Conley, J. E., Boulanger, W. J., and Mendeloff, G. L. (1966). Aortic obstruction associated with methysergide maleate therapy for headaches. J. Amer. med. Ass., 198, 808-810.","journal-title":"J. Amer. med. Ass"},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"827","DOI":"10.1097\/00007611-195508000-00006","article-title":"Sclerosing lipogranuloma","volume":"48","author":"Coppridge, W.M.; Roberts, L.C.; Hughes, J.","year":"1955","unstructured":"Coppridge, W. M., Roberts, L. C., and Hughes, J. (1955). Sclerosing lipogranuloma. Sth. med. J. (Bgham, Ala.), 48, 827-833.","journal-title":"Sth. med. J. (Bgham, Ala.)"},{"key":"ref_8","first-page":"754","article-title":"A new theory concerning the etiology of Riedel's struma","volume":"12","author":"Courcy, J.L.de","year":"1942","unstructured":"Courcy, J. L. de (1942). A new theory concerning the etiology of Riedel's struma. Surgery, 12, 754-762.","journal-title":"Surgery"},{"key":"ref_9","article-title":"In Pathology of the Connectir e Tissue Diseases","author":"Gardner, D.L.","year":"1965","unstructured":"Gardner, D. L. (1965). In Pathology of the Connectir e Tissue Diseases. Edward Arnold, London."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"160","DOI":"10.7326\/0003-4819-65-1-160","article-title":"Diagnostic problems in retroperitoneal disease","volume":"65","author":"Goodwin, W.E.; Fonkaisrud, E.W.; Goldman, R.; Kaufman, J.J.; Martin, D.C.; Riley, J.M.; Roe, C.W.; Schapiro, A.E.; Wilkerson, J.A.","year":"1966","unstructured":"Goodwin, W. E., Fonkaisrud, E. W., Goldman, R., Kaufman, J. J., Martin, D. C., Riley, J. M., Roe, C. W., Schapiro, A. E., and Wilkerson, J. A. (1966). Diagnostic problems in retroperitoneal disease. Ann. intern. Med., 65, 160-184.","journal-title":"Ann. intern. Med"},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1056\/NEJM196401092700202","article-title":"Methysergide for prevention of headache; experience in five hundred patients over three years","volume":"270","author":"Graham, J.R.","year":"1964","unstructured":"Graham, J. R. (1964). Methysergide for prevention of headache; experience in five hundred patients over three years. New Engl. J. Med., 270, 67-72.","journal-title":"New Engl. J. Med"},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1097\/00000441-196707000-00001","article-title":"Cardiac and pulmonary fibrosis during methysergide therapy for headache","volume":"254","author":"Graham, J.R.","year":"1967","unstructured":"Graham, J. R. (1967). Cardiac and pulmonary fibrosis during methysergide therapy for headache. Amer. J. med. Sci., 254, 1-12.","journal-title":"Amer. J. med. Sci"},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1002\/bjs.18004619503","article-title":"Idiopathic retroperitoneal fibrosis; a condition involving the ureters, the aorta, and the inferior vena cava","volume":"46","author":"Hackett, E.","year":"1958","unstructured":"Hackett, E. (1958). Idiopathic retroperitoneal fibrosis; a condition involving the ureters, the aorta, and the inferior vena cava. Brit. J. Surg., 46, 3-9.","journal-title":"Brit. J. Surg"},{"key":"ref_14","first-page":"929","article-title":"The extravasation and precipitation of urine in the hilus of the kidneys","volume":"24","author":"Hamperl, H.; Dallenbach, F.D.","year":"1957","unstructured":"Hamperl, H., and Dallenbach, F. D. (1957). The extravasation and precipitation of urine in the hilus of the kidneys. J. Mt Sinai Hosp., 24, 929-934.","journal-title":"J. Mt Sinai Hosp"},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1001\/jama.1962.03050400040007","article-title":"Idiopathic retroperitoneal fibrosis","volume":"182","author":"Harrow, B.R.; Sloane, J.A.","year":"1962","unstructured":"Harrow, B. R., and Sloane, J. A. (1962). Idiopathic retroperitoneal fibrosis. J. Amer. med. Ass., 182, 38-43.","journal-title":"J. Amer. med. Ass"},{"key":"ref_16","first-page":"1565","article-title":"Idiopathic retroperitoneal fibrosis","volume":"174","author":"Hinman, Jr, F.","year":"1960","unstructured":"Hinman, F., Jr. (1960). Quoted by Ormond, J. K. Idiopathic retroperitoneal fibrosis, J. Amer. med. Ass., 174, 1565.","journal-title":"J. Amer. med. Ass"},{"key":"ref_17","first-page":"765","volume-title":"Ophthalmic Pathology","author":"Hogan, M.J.","year":"1962","unstructured":"Hogan, M. J., and Zimmerman, L. E. Eds. (1962). In Ophthalmic Pathology, p. 765."},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1038\/207205a0","article-title":"Yellow fat in the wild rabbit","volume":"207","author":"Jones, D.; Gresham, G.A.Lloyd; G., H.; Howard, A.N.","year":"1965","unstructured":"Jones, D., Gresham, G. A.. Lloyd, H. G., and Howard, A. N. (1965). Yellow fat in the wild rabbit. Nature (Lond.), 207, 205-206.","journal-title":"Nature (Lond.)"},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"356","DOI":"10.1136\/ard.25.4.356","article-title":"Idiopathic retroperitoneal fibrosis associated with an arteritis","volume":"25","author":"Jones, E.A.; Alexander, M.K.","year":"1966","unstructured":"Jones, E. A., and Alexander, M. K. (1966). Idiopathic retroperitoneal fibrosis associated with an arteritis. Ann. rheum. Dis., 25, 356-360.","journal-title":"Ann. rheum. Dis"},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1111\/j.1464-410X.1967.tb09825.x","article-title":"Idiopathic retroperitoneal fibrosis. Notes on its diagnosis, management and pathogenesis","volume":"39","author":"Jose, J.S.","year":"1967","unstructured":"Jose, J. S. (1967). Idiopathic retroperitoneal fibrosis. Notes on its diagnosis, management and pathogenesis. Brit. J. Urol., 39, 431-43.","journal-title":"Brit. J. Urol"},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"284","DOI":"10.1111\/j.1464-410X.1963.tb06906.x","article-title":"Retroperitoneal vasculitis with perivascular fibrosis","volume":"35","author":"Kay, R.G.","year":"1963","unstructured":"Kay, R. G. (1963). Retroperitoneal vasculitis with perivascular fibrosis. Brit. J. Urol., 35, 284-291.","journal-title":"Brit. J. Urol"},{"key":"ref_22","first-page":"217","article-title":"Sclerosing Hodgkin's disease vs. idiopathic retroperitoneal fibrosis","volume":"86","author":"Kendall, A.R.; Lakey, W.H.","year":"1961","unstructured":"Kendall, A. R., and Lakey, W. H. (1961). Sclerosing Hodgkin's disease vs. idiopathic retroperitoneal fibrosis. J. Urol. (Baltimore), 86, 217-221.","journal-title":"J. Urol. (Baltimore)"},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1111\/j.0954-6820.1960.tb03524.x","article-title":"Periureteritis fibrosa (Gerota's fascitis)","volume":"167","author":"Lund, F.; Pedersen, J.","year":"1960","unstructured":"Lund, F., and Pedersen, J. (1960). Periureteritis fibrosa (Gerota's fascitis). Acta med. scand., 167, 105-110.","journal-title":"Acta med. scand"},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1111\/j.1464-410X.1954.tb06075.x","article-title":"Unusual conditions of the ureter and kidney","volume":"26","author":"MacLean, J.T.","year":"1954","unstructured":"MacLean, J. T. (1954). Unusual conditions of the ureter and kidney. Brit. J. Urol., 26, 127-138.","journal-title":"Brit. J. Urol"},{"key":"ref_25","first-page":"1278","article-title":"Idiopathic retroperitoneal fibrosis","volume":"122","author":"Mathisen, W.; Holta, A.L.","year":"1966","unstructured":"Mathisen, W., and Holta, A. L. (1966). Idiopathic retroperitoneal fibrosis. Surg. Gynec. Obstet., 122, 1278-1282.","journal-title":"Surg. Gynec. Obstet"},{"key":"ref_26","first-page":"447","article-title":"Bilateral ureteral obstruction due to compression by chronic retroperitoneal inflammation","volume":"68","author":"Miller, J.M.; Lipin, R.J.; Meisel, H.J.; Long, P.H.","year":"1952","unstructured":"Miller, J. M., Lipin, R. J., Meisel, H. J., and Long, P. H. (1952). Bilateral ureteral obstruction due to compression by chronic retroperitoneal inflammation. J. Urol. (Baltimore), 68, 447-451.","journal-title":"J. Urol. (Baltimore)"},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"645","DOI":"10.1136\/jcp.18.5.645","article-title":"Systemic idiopathic fibrosis and systemic Weber-Christian disease","volume":"18","author":"Mitchinson, M.J.","year":"1965","unstructured":"Mitchinson, M. J. (1965). Systemic idiopathic fibrosis and systemic Weber-Christian disease. J. clin. Path., 18, 645-649.","journal-title":"J. clin. Path"},{"key":"ref_28","article-title":"Systemic idiopathic fibrosis","author":"Mitchinson, M.J.","year":"1969","unstructured":"Mitchinson, M. J. (1969a). Systemic idiopathic fibrosis. M.D. dissertation."},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"602","DOI":"10.1016\/S0140-6736(69)90316-X","article-title":"The toxoplasma dye test in idiopathic retrop-ritoneal fibrosis","volume":"2","author":"Mitchinson, M.J.","year":"1969","unstructured":"Mitchinson, M. J. (1969b). The toxoplasma dye test in idiopathic retrop-ritoneal fibrosis. Lancet, 2, 602.","journal-title":"Lancet"},{"key":"ref_30","article-title":"Clinical aspects of idiopathic retroperitoneal fibrosis","author":"Mitchinson, M.J.","year":"1970","unstructured":"Mitchinson, M. J. (1970). Clinical aspects of idiopathic retroperitoneal fibrosis. To be published."},{"key":"ref_31","article-title":"Urinary leakage and retroperitoneal fibrosis","author":"Mitchinson, M.J.; Bird, D.R.","year":"1970","unstructured":"Mitchinson, M. J., and Bird, D. R. (1970). Urinary leakage and retroperitoneal fibrosis. J. Urol. (Baltimore). In press.","journal-title":"J. Urol"},{"key":"ref_32","first-page":"\"193","article-title":"Sur l'incidence ur6terale de la fibrose r6trop6ritoneale idiopathique extensive (a propos de 15 cas)","volume":"73","author":"Nezelof, C.; Watchi, J.M.; Auvert, J.; Xerri, A.; Couvelaire, R.","year":"1967","unstructured":"Nezelof, C., Watchi, J. M., Auvert, J., Xerri, A., and Couvelaire, R. (1967). Sur l'incidence ur6terale de la fibrose r6trop6ritoneale idiopathique extensive (a propos de 15 cas). J. Urol. Nephrol., 73, 193-229. Ohls6n, L. (1965). Retroperitoneal fibrosis due to leakage of urine. A contribution to the etiology of idiopathic retroperitoneal fibrosis. Acta Soc. Med. upsalien., 70, 231-240.","journal-title":"J. Urol. Nephrol; Retroperitoneal fibrosis due to leakage of urine. A contribution to the etiology of idiopathic retroperitoneal fibrosis"},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"685","DOI":"10.1177\/003591576005300830","article-title":"Pathology of fibrotic lesions","volume":"53","author":"Pugh, R.C.B.","year":"1960","unstructured":"Pugh, R. C. B. (1960). Pathology of fibrotic lesions. Proc. roy. Soc. Med., 53, 685-689.","journal-title":"Proc. roy. Soc. Med"},{"key":"ref_34","first-page":"159","article-title":"Retroperitoneal fibrosis: a radiological and follow-up study of fourteen cases","volume":"38","author":"Saxton, H.M.; Kilpatrick, F.R.; Kinder, C.H.; Lessof, M.H.; McHardy-Young, S.; Wardle, D.F.H.","year":"1969","unstructured":"Saxton, H. M., Kilpatrick, F. R., Kinder, C. H., Lessof, M. H., McHardy-Young, S., and Wardle, D. F. H. (1969). Retroperitoneal fibrosis: a radiological and follow-up study of fourteen cases. Quart. J. Med., 38, 159-181.","journal-title":"Quart. J. Med"},{"key":"ref_35","article-title":"Bilateral ureteral obstruction due to envelopment and compression by an inflammatory retroperitoneal process: report of 2 cases","author":"Shaheen, D.J.; Johnston, A.","year":"1959","unstructured":"Shaheen, D. J., and Johnston, A. (1959). Bilateral ureteral obstruction due to envelopment and compression by an inflammatory retroperitoneal process: report of 2 cases."},{"key":"ref_36","doi-asserted-by":"crossref","first-page":"753","DOI":"10.1111\/j.1464-410X.1967.tb09859.x","article-title":"Calycorenal backflow","volume":"39","author":"Stapor, K.","year":"1967","unstructured":"Stapor, K. (1967). Calycorenal backflow. Brit. J. Urol., 39, 753-758.","journal-title":"Brit. J. Urol"},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"596","DOI":"10.1177\/003591576605900704","article-title":"Riedel's thyroiditis and retroperitoneal fibrosis","volume":"59","author":"Turner-Warwick, R.; Nabarro, J.D.N.; Doniach, D.(1966","unstructured":"Turner-Warwick, R., Nabarro, J. D. N., and Doniach, D.(1966). Riedel's thyroiditis and retroperitoneal fibrosis. Proc. roy. Soc. Med., 59, 596-598.","journal-title":"Proc. roy. Soc. Med"},{"key":"ref_38","first-page":"657","article-title":"Multifocal idiopathic fibromatosis","volume":"53","author":"Ullmann, A.S.; Dacso, M.R.","year":"1968","unstructured":"Ullmann, A. S., and Dacso, M. R. (1968). Multifocal idiopathic fibromatosis. Dis. Chest., 53, 657-659.","journal-title":"Dis. Chest"},{"key":"ref_39","doi-asserted-by":"crossref","first-page":"508","DOI":"10.1002\/bjs.1800540603","article-title":"Non-malignant retroperitoneal fibrosis","volume":"54","author":"Webb, A.J.; Dawson-Edwards, P.","year":"1967","unstructured":"Webb, A. J., and Dawson-Edwards, P. (1967). Non-malignant retroperitoneal fibrosis. Brit. J. Surg., 54, 508-518.","journal-title":"Brit. J. Surg"},{"key":"ref_40","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1210\/jcem-17-2-201","article-title":"Invasive fibrous thyroiditis (Riedel's struma)","volume":"17","year":"1957","unstructured":"Woolner, L. B., McConahey, W. M., and Beahrs, 0. H. (1957). Invasive fibrous thyroiditis (Riedel's struma). J. clin. Endocr., 17, 201-220.","journal-title":"J. clin. Endocr"}],"container-title":["Journal of Clinical Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/jcp.23.8.681","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,31]],"date-time":"2024-05-31T06:03:43Z","timestamp":1717135423000},"score":1,"resource":{"primary":{"URL":"https:\/\/jcp.bmj.com\/lookup\/doi\/10.1136\/jcp.23.8.681"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1970,11]]},"references-count":40,"journal-issue":{"issue":"8","published-online":{"date-parts":[[1970,11,1]]},"published-print":{"date-parts":[[1970,11]]}},"alternative-id":["10.1136\/jcp.23.8.681"],"URL":"https:\/\/doi.org\/10.1136\/jcp.23.8.681","relation":{},"ISSN":["0021-9746","1472-4146"],"issn-type":[{"value":"0021-9746","type":"print"},{"value":"1472-4146","type":"electronic"}],"subject":[],"published":{"date-parts":[[1970,11]]}}}