{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,14]],"date-time":"2025-12-14T16:13:14Z","timestamp":1765728794252,"version":"3.48.0"},"reference-count":37,"publisher":"BMJ","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Clin Pathol"],"published-print":{"date-parts":[[1971,5]]},"abstract":"<jats:p>A family is described many of whose members suffered from renal insufficiency, hypertension, gout, and hyperuricaemia in conjunction. Adequate information was obtained on 72 subjects from five generations. In 17, one or more of the above mentioned abnormalities was or had been present. The hereditary distribution suggested an autosomal dominant disease entity.<\/jats:p>\n                  <jats:p>The renal disease was characterized by an early loss of urinary concentrating power, minimal proteinuria, and death at a relatively early age dominating the clinical picture.<\/jats:p>\n                  <jats:p>The histological picture in three biopsies and one necropsy showed predominant tubular atrophy and interstitial fibrosis, with striking tubular basement membrane thickening.<\/jats:p>\n                  <jats:p>It is suggested that these patients suffered from a hereditary degenerative renal disease. The question whether hyperuricaemia was primary or secondary in these cases is discussed.<\/jats:p>","DOI":"10.1136\/jcp.24.4.354","type":"journal-article","created":{"date-parts":[[2007,6,9]],"date-time":"2007-06-09T00:50:46Z","timestamp":1181350246000},"page":"354-359","source":"Crossref","is-referenced-by-count":23,"title":["An unusual form of renal disease associated with gout and hypertension"],"prefix":"10.1136","volume":"24","author":[{"given":"W.","family":"Van Goor","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C. J.","family":"Kooiker","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E. J. Dorhout","family":"Mees","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[1971,5,1]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1159\/000179585","article-title":"The value of the renal biopsy in unilateral renovascular hypertension","volume":"4","author":"Barajas, L.; Lupu, A.N.; Kaufman, J.J.; Latta, H.; Maxwell, M.H.","year":"1967","unstructured":"Barajas, L., Lupu, A. N., Kaufman, J. J., Latta, H., and Maxwell, M. H. (1967). The value of the renal biopsy in unilateral renovascular hypertension. Nephron, 4, 231-247.","journal-title":"Nephron"},{"key":"ref_2","first-page":"79","article-title":"Renal disease in primary gout","volume":"37","author":"Barlow, K.A.; Beilin, L.J.","year":"1968","unstructured":"Barlow, K. A., and Beilin, L. J. (1968). Renal disease in primary gout. Quart. J. Med., 37, 79-96.","journal-title":"Quart. J. 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Metabolism, 6, 230-243.","journal-title":"Metabolism"},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1001\/archinte.1962.03620160005002","article-title":"The pathogenesis of gout","volume":"109","author":"Sorensen, L.B.","year":"1962","unstructured":"Sorensen, L. B. (1962). The pathogenesis of gout. Arch. intern. Med., 109, 379-390.","journal-title":"Arch. intern. Med"},{"year":"1966","author":"Stanbury, J.B.; Wijngaarden, J.B.; Fredrickson, D.S.","key":"ref_19","unstructured":"Stanbury, J. B., Wijngaarden, J. B., and Fredrickson, D. S. (1966)."},{"key":"ref_20","first-page":"405","article-title":"The kidney in gout","volume":"39","author":"Talbott, J.H.; Terplan, K.L.","year":"1960","unstructured":"Talbott, J. H., and Terplan, K. L. (1960). The kidney in gout. 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BROWN 62ip ($1.50)"}],"container-title":["Journal of Clinical Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/jcp.24.4.354","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,12,14]],"date-time":"2025-12-14T16:03:55Z","timestamp":1765728235000},"score":1,"resource":{"primary":{"URL":"https:\/\/jcp.bmj.com\/lookup\/doi\/10.1136\/jcp.24.4.354"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1971,5]]},"references-count":37,"journal-issue":{"issue":"4","published-online":{"date-parts":[[1971,5,1]]},"published-print":{"date-parts":[[1971,5]]}},"alternative-id":["10.1136\/jcp.24.4.354"],"URL":"https:\/\/doi.org\/10.1136\/jcp.24.4.354","relation":{},"ISSN":["0021-9746","1472-4146"],"issn-type":[{"type":"print","value":"0021-9746"},{"type":"electronic","value":"1472-4146"}],"subject":[],"published":{"date-parts":[[1971,5]]}}}