{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,14]],"date-time":"2025-12-14T05:55:50Z","timestamp":1765691750796,"version":"3.48.0"},"reference-count":12,"publisher":"BMJ","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Clin Pathol"],"published-print":{"date-parts":[[1972,1]]},"abstract":"<jats:p>The present study was designed to compare the Thyopac and Triosorb triiodothyronine uptake tests. A normal range was established for the two procedures. Neither test was affected by iodine-containing drugs or contrast media but abnormal results were obtained during pregnancy and in subjects receiving oestrogens. Both tests proved satisfactory in the diagnosis of hypo- and hyperthyroidism, giving results consistent with clinical assessment and with serum protein-bound iodine determinations. The Thyopac procedure was preferred for a number of reasons. It requires less plasma; it is slightly simpler and quicker and it is not time dependent.<\/jats:p>","DOI":"10.1136\/jcp.25.1.30","type":"journal-article","created":{"date-parts":[[2007,6,9]],"date-time":"2007-06-09T00:50:46Z","timestamp":1181350246000},"page":"30-35","source":"Crossref","is-referenced-by-count":10,"title":["Comparison of two triiodothyronine uptake techniques for the assessment of thyroid function"],"prefix":"10.1136","volume":"25","author":[{"given":"Vivian","family":"Chan","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joan","family":"McAlister","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"Landon","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[1972,1,1]]},"reference":[{"key":"ref_1","article-title":"Technical Bulletin 69\/7 on Thyopac-3","author":"Clark, F.","year":"1969","unstructured":"Clark, F. (1969). Technical Bulletin 69\/7 on Thyopac-3. Radiochemical Centre, Amersham."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"713","DOI":"10.1136\/bmj.1.5698.713","article-title":"Evaluation of Thyopac-3 test in the in-vitro assessment of thyroid function","volume":"1","author":"Clark, F.; Brown, H.J.","year":"1970","unstructured":"Clark, F., and Brown, H. J. (1970a). Evaluation of Thyopac-3 test in the in-vitro assessment of thyroid function. Brit. med. J., 1, 713-715.","journal-title":"Brit. med. J"},{"key":"ref_3","first-page":"543","article-title":"Free thyroxine index. Brit. nmed","volume":"2","author":"Clark, F.; Brown, H.J.","year":"1970","unstructured":"Clark, F., and Brown, H. J. (1970b). Free thyroxine index. Brit. nmed. J., 2, 543.","journal-title":"J"},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1210\/jcem-25-1-39","article-title":"Assessment of thyroid function by the combined use of the serum protein-bound iodine and resin uptake of \"'TI-triiodothyronine","volume":"25","author":"Clark, F.; Horn, D.B.","year":"1965","unstructured":"Clark, F., and Horn, D. B. (1965). Assessment of thyroid function by the combined use of the serum protein-bound iodine and resin uptake of \"'TI-triiodothyronine. J. clin. Endocr., 25, 39-45.","journal-title":"J. clin. Endocr"},{"key":"ref_5","first-page":"243","article-title":"An assessment of the triiodothyronine uptake test using a diagnostic kit","volume-title":"Symposium on In-vitro Procedures with Radioisotopes in Medicine, Vienna","author":"Goodhead, L.; McAlister, J.M.","year":"1970","unstructured":"Goodhead, L., and McAlister, J. M. (1970). An assessment of the triiodothyronine uptake test using a diagnostic kit. In Symposium on In-vitro Procedures with Radioisotopes in Medicine, Vienna, pp. 243-255."},{"key":"ref_6","first-page":"12","article-title":"Thyroid status in pregnancy and in women taking oral contraceptives","volume":"1","author":"Goolden, A.W.G.; Gartside, June M.; Sanderson, C.","year":"1967","unstructured":"Goolden, A. W. G., Gartside, June M., and Sanderson, C. (1967). Thyroid status in pregnancy and in women taking oral contraceptives. Lancet, 1, 12-15.","journal-title":"Lancet"},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1210\/jcem-17-1-33","article-title":"The thyroid hormone plasma protein complex in man. II. A new in vitro method for study of 'uptake of labelled hormonal components by human erythrocytes'","volume":"17","author":"Hamolsky, M.W.; Stein, M.; Freedberg, A.S.","year":"1957","unstructured":"Hamolsky, M. W., Stein, M., and Freedberg, A. S. (1957). The thyroid hormone plasma protein complex in man. II. A new in vitro method for study of 'uptake of labelled hormonal components by human erythrocytes'. J. clin. Endocr., 17 33-44.","journal-title":"J. clin. Endocr"},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"224","DOI":"10.1016\/S0140-6736(69)91240-9","article-title":"Clinical application of serum-total-thyroxine estimation, resin uptake and freethyroxine index","volume":"1","author":"Howorth, P.J.N.; MacLagan, N.F.","year":"1969","unstructured":"Howorth, P. J. N., and MacLagan, N. F. (1969). Clinical application of serum-total-thyroxine estimation, resin uptake and freethyroxine index. Lancet, 1, 224-228.","journal-title":"Lancet"},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"599","DOI":"10.1093\/ajcp\/49.4_ts.599","article-title":"Free thyroxine factor and a PBI-T, uptake nonogram","volume":"49","author":"Kintner, E.P.","year":"1968","unstructured":"Kintner, E. P. (1968). Free thyroxine factor and a PBI-T, uptake nonogram. Amer. J. clin. Path., 49, 599-601.","journal-title":"Amer. J. clin. Path"},{"key":"ref_10","first-page":"1474","article-title":"The in vitro resin sponge uptake of triiodothyrocine-Ill\"","volume":"20","author":"Mitchell, M.L.; Harden, A.B.; O'Rourke, M.E.","year":"1960","unstructured":"Mitchell, M. L., Harden, A. B., and O'Rourke, M. E. (1960). The in vitro resin sponge uptake of triiodothyrocine-Ill\". J. clln. Endocr., 20, 1474-1483.","journal-title":"J. clln. Endocr"},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"456","DOI":"10.1210\/jcem-21-4-456","article-title":"Resin uptake of''l1-Triiodothyronine as a test of tbyroid function","volume":"21","author":"Sterling, K.; Tabachnick, M.","year":"1961","unstructured":"Sterling, K., and Tabachnick, M. (1961). Resin uptake of''l1-Triiodothyronine as a test of tbyroid function. J. clin. Endocr., 21, 456-464.","journal-title":"J. clin. 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