{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,6]],"date-time":"2025-12-06T05:35:30Z","timestamp":1764999330441,"version":"3.46.0"},"reference-count":4,"publisher":"BMJ","issue":"11","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Clin Pathol"],"published-print":{"date-parts":[[1972,11]]},"DOI":"10.1136\/jcp.25.11.1008-c","type":"journal-article","created":{"date-parts":[[2007,6,9]],"date-time":"2007-06-09T00:50:46Z","timestamp":1181350246000},"page":"1008.3-1009","source":"Crossref","is-referenced-by-count":2,"title":["Antenatal diagnosis."],"prefix":"10.1136","volume":"25","author":[{"given":"P E","family":"Polani","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[1972,11,1]]},"reference":[{"key":"ref_1","first-page":"849","volume":"1","author":"Lobb, D.S.; Reeves, B.R.; Lawler, S.D.","year":"1972","unstructured":"Lobb, D. S., Reeves, B. R., and Lawler, S. D. (1972). Lancet, 1, 849.","journal-title":"Lancet"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1038\/230167a0","volume":"230","author":"O'Riordan, M.L.; Robinson, J.A.; Buckton, K.E.; Evans, H.J.","year":"1971","unstructured":"O'Riordan, M. L., Robinson, J. A., Buckton, K. E., and Evans, H. J. (1971). Nature (Lond.), 230, 167.","journal-title":"Nature (Lond.)"},{"issue":"159","key":"ref_3","volume":"14","author":"Reeves, B.R.; Lobb, D.S.; Lawler, S.D.","year":"1972","unstructured":"Reeves, B. R., Lobb, D. S., and Lawler, S. D. (1972). Humangenetik, 14,159.","journal-title":"Humangenetik"},{"article-title":"London) Prenatal diagnosis follows a number of different approaches directed at preventing or detecting fetal abnormality and, when The Association of Clinical Pathologists: 89th general meeting this is present, treating it, perhaps curing it, or when the condition is grave and untreatable and in keeping with the unbearable anxiety that it generates in the mother, or better the parents, and in conformity with their wishes, terminating the undesired pregnancy at a stage when this is morally and legally acceptable. Disregarding the detection of gross developmental malformations by contrast radiography, ultrasonic scanning or fetoscopy, the favoured procedure for the detection of anomalies leading to serious and intractable handicap is early amniocentesis. The study of the fluid and cells is useful in respect of four main groups of anomalies","author":"Unit, Guy's Hospital","key":"ref_4","unstructured":"Unit, Guy's Hospital, London) Prenatal diagnosis follows a number of different approaches directed at preventing or detecting fetal abnormality and, when The Association of Clinical Pathologists: 89th general meeting this is present, treating it, perhaps curing it, or when the condition is grave and untreatable and in keeping with the unbearable anxiety that it generates in the mother, or better the parents, and in conformity with their wishes, terminating the undesired pregnancy at a stage when this is morally and legally acceptable. Disregarding the detection of gross developmental malformations by contrast radiography, ultrasonic scanning or fetoscopy, the favoured procedure for the detection of anomalies leading to serious and intractable handicap is early amniocentesis. The study of the fluid and cells is useful in respect of four main groups of anomalies."}],"container-title":["Journal of Clinical Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/jcp.25.11.1008-c","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,12,6]],"date-time":"2025-12-06T05:33:59Z","timestamp":1764999239000},"score":1,"resource":{"primary":{"URL":"https:\/\/jcp.bmj.com\/lookup\/doi\/10.1136\/jcp.25.11.1008-c"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1972,11]]},"references-count":4,"journal-issue":{"issue":"11","published-online":{"date-parts":[[1972,11,1]]},"published-print":{"date-parts":[[1972,11]]}},"alternative-id":["10.1136\/jcp.25.11.1008-c"],"URL":"https:\/\/doi.org\/10.1136\/jcp.25.11.1008-c","relation":{},"ISSN":["0021-9746","1472-4146"],"issn-type":[{"type":"print","value":"0021-9746"},{"type":"electronic","value":"1472-4146"}],"subject":[],"published":{"date-parts":[[1972,11]]}}}