{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,21]],"date-time":"2025-11-21T17:19:35Z","timestamp":1763745575007,"version":"3.45.0"},"reference-count":13,"publisher":"BMJ","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Clin Pathol"],"published-print":{"date-parts":[[1972,5]]},"abstract":"<jats:p>Screening tests\u2014absorbed fluorescent treponemal (FTA-ABS), the Reiter protein complement-fixation (RPCFT), VDRL slide test, automated reagin\u2014and cardiolipin Wassermann reaction\u2014were carried out on 1922 consecutive new patients attending the Whitechapel Clinic over a three-month period.<\/jats:p>\n                  <jats:p>Taking the FTA-ABS test results as an index, the most efficient combination of conventional tests was found to be the RPCFT and automated reagin test. The cardiolipin WR proved to be under-sensitive and of little value compared with the other tests.<\/jats:p>\n                  <jats:p>Forty-two per cent of the 107 sera reactive in the FTA-ABS test were not detected by the RPCFT or ART tests. An assessment based on the TPI test results and clinical findings in these patients is presented.<\/jats:p>\n                  <jats:p>The scope and limitations of the FTA-ABS test as a screening procedure are discussed.<\/jats:p>","DOI":"10.1136\/jcp.25.5.437","type":"journal-article","created":{"date-parts":[[2007,6,9]],"date-time":"2007-06-09T00:50:46Z","timestamp":1181350246000},"page":"437-440","source":"Crossref","is-referenced-by-count":5,"title":["A comparison of the absorbed fluorescent treponemal antibody (FTA-ABS) test and other screening tests for treponemal disease in patients attending a venereal disease clinic"],"prefix":"10.1136","volume":"25","author":[{"given":"A. E.","family":"Wilkinson","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G.","family":"Scrimgeour","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P.","family":"Rodin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[1972,5,1]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"549","DOI":"10.1001\/jama.1968.03140080009003","article-title":"The TPI and FTA-ABS tests in treated late syphilis","volume":"203","author":"Atssood, W.G.; Miller, J.L.; Stout, G.W.; Norins, L.C.","year":"1968","unstructured":"Atssood, W. G., Miller, J. L., Stout, G. W., and Norins, L. C. (1968). The TPI and FTA-ABS tests in treated late syphilis. J. Amer. ned. Ass., 203, 549-551.","journal-title":"J. Amer. ned. Ass"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"322","DOI":"10.1001\/archderm.1970.04000090084014","article-title":"FTA-ABS test in pregnancy. A probable false positive reaction","volume":"102","author":"Buchanan, C.S.; Haserick, J.R.","year":"1970","unstructured":"Buchanan, C. S., and Haserick, J. R. (1970). FTA-ABS test in pregnancy. A probable false positive reaction. Arch. Derm., 102, 322-325.","journal-title":"Arch. Derm"},{"key":"ref_3","first-page":"83","article-title":"Aninvestigation of sorbing substances in the FTA-ABS test for syphilis","unstructured":"Cannefax, G. R., Hanson, A. W., andSkaggs,R.,Jr,(1968).Aninvestigation of sorbing substances in the FTA-ABS test for syphilis. Publ. Hith Rep. (Wash.), 83,411-416.","journal-title":"Publ. Hith Rep. (Wash.)"},{"key":"ref_4","article-title":"Serologic reactivity in consecutive patients admitted to a general hospital. Archl","author":"Cohen, P.; Stout, G.; Ende, N.","year":"1969","unstructured":"Cohen, P., Stout, G., and Ende, N. (1969). Serologic reactivity in consecutive patients admitted to a general hospital. Archl."},{"key":"ref_5","series-title":"Proceedings of the World Forum on Syphilis and Other Treponematoses","first-page":"254","article-title":"Influence of macroglobulins on the specificity of fluorescent treponemal antibody (FTA) test for syphilis","volume":"997","author":"Fife, E.","year":"1964","unstructured":"Fife, E. (1964). Influence of macroglobulins on the specificity of fluorescent treponemal antibody (FTA) test for syphilis. In Proceedings of the World Forum on Syphilis and Other Treponematoses (US Public Health Service Publication No. 997), pp. 254-257."},{"key":"ref_6","article-title":"An improved","author":"Hunter, E.F.; Deacon, W.E.; Meyer, P.E.","year":"1964","unstructured":"Hunter, E. F., Deacon, W. E., and Meyer, P. E. (1964). An improved"},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"1287","DOI":"10.1056\/NEJM197006042822303","article-title":"Fluorescent treponemal antibody-absorption test reactions in lupus erythematous: atypical beading pattern and probable falsepositive reactions","volume":"282","author":"Kraus, S.J.; Haserick, J.R.; Lantz, M.A.","year":"1970","unstructured":"Kraus, S. J., Haserick, J. R., and Lantz, M. A. (1970). Fluorescent treponemal antibody-absorption test reactions in lupus erythematous: atypical beading pattern and probable falsepositive reactions. New Engl. J. Med., 282, 1287-1290.","journal-title":"New Engl. J. Med"},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1093\/ajcp\/50.1.52","article-title":"Automation of a flocculation test for syphilis","volume":"50","author":"McGrew, B.E.; DuCros, M.J.F.; Stout, G.W.; Falcone, V.H.","year":"1968","unstructured":"McGrew, B. E., DuCros, M. J. F., Stout, G. W., and Falcone, V. H. (1968). Automation of a flocculation test for syphilis. Amier. J. clin. Path., 50, 52-59.","journal-title":"Amier. J. clin. Path"},{"key":"ref_9","first-page":"278","article-title":"Evaluation of modified FTA-ABS test: multispot FTA-ABS","volume":"46","author":"O'Neill, P.; Johnson, G.D.; Nicol, C.S.","year":"1970","unstructured":"O'Neill, P., Johnson, G. D., and Nicol, C. S. (1970). Evaluation of modified FTA-ABS test: multispot FTA-ABS. Brit. J. *ener. Dis., 46, 278-283.","journal-title":"Brit. J. *ener. Dis"},{"key":"ref_10","first-page":"295","article-title":"Evaluation of the sorbents used in the FTA-ABS test","volume":"44","author":"Rathlev, T.","year":"1968","unstructured":"Rathlev, T. (1968). Evaluation of the sorbents used in the FTA-ABS test. Brit. J. vener. Dis., 44, 295-298.","journal-title":"Brit. J. vener. 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Dis"},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"422","DOI":"10.1177\/003591577106400439","article-title":"The role of sorbent in the absorbed fluorescent treponemal antibody (FI TA-ABS) test","volume":"64","author":"Wil'kinson, A.E.; Wiseman, C.C.","year":"1971","unstructured":"Wil'kinson, A. E., and Wiseman, C. C. (1971). The role of sorbent in the absorbed fluorescent treponemal antibody (FI TA-ABS) test. Proc. roy. Soc. Med., 64, 422-425.","journal-title":"Proc. roy. Soc. 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