{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,26]],"date-time":"2025-09-26T00:21:43Z","timestamp":1758846103755,"version":"3.44.0"},"reference-count":12,"publisher":"BMJ","issue":"9","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Clin Pathol"],"published-print":{"date-parts":[[1972,9]]},"abstract":"<jats:p>The skin surface biopsy technique has been used to investigate the erythrasma organism <jats:italic>in situ<\/jats:italic> in the stratum corneum in 11 patients. Staining by PAS and Gram stain showed the presence of a large number of organisms arranged haphazardly in some areas and in microcolonies in others. With the scanning electron microscope it was possible to see that smooth filamentous chains of microorganisms had penetrated horn cells and caused disturbance of the surface structure of these cells.<\/jats:p>\n               <jats:p>Enzyme histochemical tests showed that the erythrasma microorganism possessed a strong reactivity for NAD diaphorase and other mitochondrial enzymes. The reactivity was focal confirming a complex subcellular organization of organelles.<\/jats:p>\n               <jats:p>It is suggested that the erythrasma microorganism secretes a mucopolysaccharide sheath in some circumstances.<\/jats:p>","DOI":"10.1136\/jcp.25.9.799","type":"journal-article","created":{"date-parts":[[2007,6,9]],"date-time":"2007-06-09T00:50:46Z","timestamp":1181350246000},"page":"799-803","source":"Crossref","is-referenced-by-count":4,"title":["The erythrasma microorganism <i>in situ:<\/i> studies using the skin surface biopsy technique"],"prefix":"10.1136","volume":"25","author":[{"given":"R.","family":"Marks","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"N. D.","family":"Ramnarain","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B.","family":"Bhogal","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"N. T.","family":"Moore","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[1972,9,1]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"272","DOI":"10.1111\/j.1365-2133.1972.tb02228.x","article-title":"Scanning electron microscopy ofthe Stratum corneum","volume":"86","author":"Dawber, R.P.R.; Marks, R.; Swift, J.A.","year":"1972","unstructured":"Dawber, R. P. R., Marks, R., and Swift, J. A. (1972). Scanning electron microscopy ofthe Stratum corneum. Brit. J. Derm., 86, 272-281.","journal-title":"Brit. J. Derm"},{"key":"ref_2","first-page":"160","article-title":"A new approach to the cytochemical localization of enzymes","volume":"142","author":"Holt, S.J.","year":"1954","unstructured":"Holt, S. J. (1954). A new approach to the cytochemical localization of enzymes. Proc. roy. Soc. B., 142, 160-169.","journal-title":"Proc. roy. Soc. B"},{"key":"ref_3","first-page":"84","article-title":"Skin surface biopsy","author":"Marks, R.; Dawber, R.P.R.","year":"1971","unstructured":"Marks, R., and Dawber, R. P. R. (1971). Skin surface biopsy. Brit. J. Derm., 84,117-123.","journal-title":"Brit. J. Derm"},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1001\/archderm.1972.01620050030005","article-title":"In situ microbiology of the stratum corneum","volume":"105","author":"Marks, R.; Dawber, R.P.R.","year":"1972","unstructured":"Marks, R., and Dawber, R. P. R. (1972). In situ microbiology of the stratum corneum. Arch. Derm., 105, 216-221.","journal-title":"Arch. Derm"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1007\/BF00508072","article-title":"Zum histochemischen Nachweis von Enzymen des energieliefernden Stoffwechsels in Dermatophyten der Gattungen Microsporum Epidermophyton und Keratinomyces","volume":"232","author":"Meinhof, W.","year":"1968","unstructured":"Meinhof, W. (1968). Zum histochemischen Nachweis von Enzymen des energieliefernden Stoffwechsels in Dermatophyten der Gattungen Microsporum Epidermophyton und Keratinomyces. Arch. klin. exp. Derm., 232, 279-294.","journal-title":"Arch. klin. exp. Derm"},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"474","DOI":"10.1038\/jid.1967.168","article-title":"Bacterial invasion of the Stratum corneum in erythrasma","volume":"49","author":"Montes, L.F.; Black, S.H.; McBride, M.E.","year":"1967","unstructured":"Montes, L. F., Black, S. H., and McBride, M. E. (1967). Bacterial invasion of the Stratum corneum in erythrasma. J. invest. Derm., 49, 474-485.","journal-title":"J. invest. Derm"},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"264","DOI":"10.1177\/5.3.264","article-title":"The histochemical demonstration of leucine aminopeptidase","volume":"5","author":"Nachlas, M.M.; Crawford, D.T.; Seligman, A.M.","year":"1957","unstructured":"Nachlas, M. M., Crawford, D. T., and Seligman, A. M. (1957). The histochemical demonstration of leucine aminopeptidase. J. Histochem. Cytochem., 5, 264-278.","journal-title":"J. Histochem. Cytochem"},{"key":"ref_8","article-title":"Histochemistry; Theoretical and Applied","author":"Pearse, A.G.E.","year":"1960","unstructured":"Pearse, A. G. E. (1960). Histochemistry; Theoretical and Applied, 2nd ed. Churchill, London.","edition":"2nd ed"},{"key":"ref_9","first-page":"283","article-title":"The etiology and treatment of erythrasma","volume":"37","author":"Sarkany, I.; Taplin, D.; Blank, H.","year":"1961","unstructured":"Sarkany, I., Taplin, D., and Blank, H. (1961). The etiology and treatment of erythrasma. J. invest. Derm., 37, 283-290.","journal-title":"J. invest. Derm"},{"issue":"8","key":"ref_10","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1111\/j.1365-2133.1972.tb15409.x","article-title":"The microbiology of the cutaneous diphtheroids","volume":"86","author":"Som, rville; A, D.","year":"1972","unstructured":"Som:rville, D. A. (1972). The microbiology of the cutaneous diphtheroids. Brit. J. Derm., 86, Suppl. 8, 16-20.","journal-title":"Brit. J. Derm"},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1099\/00222615-3-1-57","article-title":"Erythrasma in normal young adults","volume":"3","author":"Somerville, D.A.","year":"1970","unstructured":"Somerville, D. A. (1970). Erythrasma in normal young adults. J. med. Microbiol., 3, 57-64.","journal-title":"J. med. Microbiol"},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1177\/8.5.387","article-title":"Histochemical demonstration of mitochondrial adenosine triphosphatase with the lead-adenosine triphosphate technique","volume":"8","author":"Wachstein, M.; Meisel, E.; Niedzwiedz, A.","year":"1960","unstructured":"Wachstein, M., Meisel, E., and Niedzwiedz, A. (1960). Histochemical demonstration of mitochondrial adenosine triphosphatase with the lead-adenosine triphosphate technique. J. Histochem. Cytochem., 8, 387-388.","journal-title":"J. Histochem. Cytochem"}],"container-title":["Journal of Clinical Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/jcp.25.9.799","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,9,25]],"date-time":"2025-09-25T17:29:26Z","timestamp":1758821366000},"score":1,"resource":{"primary":{"URL":"https:\/\/jcp.bmj.com\/lookup\/doi\/10.1136\/jcp.25.9.799"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1972,9]]},"references-count":12,"journal-issue":{"issue":"9","published-online":{"date-parts":[[1972,9,1]]},"published-print":{"date-parts":[[1972,9]]}},"alternative-id":["10.1136\/jcp.25.9.799"],"URL":"https:\/\/doi.org\/10.1136\/jcp.25.9.799","relation":{},"ISSN":["0021-9746","1472-4146"],"issn-type":[{"type":"print","value":"0021-9746"},{"type":"electronic","value":"1472-4146"}],"subject":[],"published":{"date-parts":[[1972,9]]}}}