{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,5]],"date-time":"2026-06-05T03:03:30Z","timestamp":1780628610861,"version":"3.54.1"},"reference-count":39,"publisher":"BMJ","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Clin Pathol"],"published-print":{"date-parts":[[1973,2]]},"abstract":"<jats:p>Eight patients with <jats:italic>E. coli<\/jats:italic> septicaemia had oliguric renal failure which was associated with haematological evidence of intravascular coagulation. Five of these patients also had the characteristic blood picture of microangiopathic haemolytic anaemia.<\/jats:p>\n               <jats:p>In an attempt to prevent further deposition of fibrin, intravenous heparin was administered to six patients, three of whom recovered fully and three died.<\/jats:p>\n               <jats:p>The diagnosis of intravascular coagulation was subsequently confirmed by histological examination of necropsy material and it is suggested that some of the complications of <jats:italic>E. coli<\/jats:italic> septicaemia may be attributable to disseminated intravascular coagulation.<\/jats:p>","DOI":"10.1136\/jcp.26.2.120","type":"journal-article","created":{"date-parts":[[2007,6,9]],"date-time":"2007-06-09T00:50:46Z","timestamp":1181350246000},"page":"120-125","source":"Crossref","is-referenced-by-count":7,"title":["Intravascular coagulation and <i>E. coli<\/i> septicaemia"],"prefix":"10.1136","volume":"26","author":[{"given":"F. E.","family":"Preston","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R. G.","family":"Malia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M. J.","family":"Sworn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E. K.","family":"Blackburn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[1973,2,1]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"1086","DOI":"10.1172\/JCI103885","article-title":"Themechanismof clot dissolution by plasmin","volume":"38","author":"Alkjaersig, N.; Fletcher, A.P.; Sherry, S.","year":"1959","unstructured":"Alkjaersig, N., Fletcher, A. P., and Sherry, S. (1959). Themechanismof clot dissolution by plasmin. J. clin. Invest., 38, 1086-1095.","journal-title":"J. clin. 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