{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T16:45:54Z","timestamp":1792169154398,"version":"4.4.0"},"reference-count":25,"publisher":"BMJ","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Clin Pathol"],"published-print":{"date-parts":[[1973,5]]},"abstract":"<jats:p>Mallory's (`alcoholic') hyaline has been found in hepatocytes in 18 of 70 patients with primary biliary cirrhosis. These inclusions have previously been noted in only three cases of primary biliary cirrhosis. Current views on the nature of Mallory's hyaline are briefly discussed.<\/jats:p>","DOI":"10.1136\/jcp.26.5.340","type":"journal-article","created":{"date-parts":[[2007,6,9]],"date-time":"2007-06-09T00:50:46Z","timestamp":1181350246000},"page":"340-342","source":"Crossref","is-referenced-by-count":21,"title":["Mallory's (`alcoholic') hyaline in primary biliary cirrhosis"],"prefix":"10.1136","volume":"26","author":[{"given":"Roderick N. M.","family":"MacSween","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[1973,5,1]]},"reference":[{"key":"ref_1","first-page":"278","article-title":"Mallory bodies in chronic cholestasis","volume":"58","author":"Ament, M.; Fenster, L.F.","year":"1970","unstructured":"Ament, M., and Fenster, L. F. (1970). Mallory bodies in chronic cholestasis. (Abstr.) Gastroenterology, 58, 278.","journal-title":"(Abstr.) Gastroenterology"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1016\/S0016-5085(19)36338-3","article-title":"Posthepatitic and alcoholic cirrhosis: clinico-pathologic study of 43 cases of each","volume":"22","author":"Baggenstoss, A.H.; Stauffer, M.H.","year":"1952","unstructured":"Baggenstoss, A. H., and Stauffer, M. H. (1952). Posthepatitic and alcoholic cirrhosis: clinico-pathologic study of 43 cases of each. Gastroenterology, 22, 157-180.","journal-title":"Gastroenterology"},{"key":"ref_3","first-page":"527","article-title":"The nature of alcoholic hyaline","volume":"10","author":"Becker, B.J.P.","year":"1961","unstructured":"Becker, B. J. P. (1961). The nature of alcoholic hyaline. Lab. Invest., 10, 527-534.","journal-title":"Lab. Invest"},{"key":"ref_4","first-page":"301","article-title":"Mallory alcoholic hyalin: a heretofore unique lesion of hepatocellular ergastoplasm","volume":"13","author":"Biava, C.","year":"1964","unstructured":"Biava, C. (1964). Mallory alcoholic hyalin: a heretofore unique lesion of hepatocellular ergastoplasm. Lab. Invest., 13, 301-320.","journal-title":"Lab. Invest"},{"key":"ref_5","article-title":"Tumours of the Liver and Intrahepatic Bile Duct. Atlas of Tumor Pathology, Sect","author":"Edmondson, H.A.","year":"1958","unstructured":"Edmondson, H. A. (1958). Tumours of the Liver and Intrahepatic Bile Duct. Atlas of Tumor Pathology, Sect. VII, fasc."},{"key":"ref_6","first-page":"441","article-title":"An electron microscopic study of alcoholic hyalin","volume":"44","author":"Armed Forces Institute of Pathology Washington, D.C.Flax; H., M.; Tisdale, W.A.","year":"1964","unstructured":"Armed Forces Institute of Pathology Washington, D.C. Flax, M. H., and Tisdale, W. A. (1964). An electron microscopic study of alcoholic hyalin. Amer. J. Path., 44, 441-454.","journal-title":"Amer. J. 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Heinemann, London."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"669","DOI":"10.1016\/S0016-5085(19)35194-7","article-title":"Postnecrotic cirrhosis in alcoholics","volume":"39","author":"Popper, H.; Rubin, E.; Krus, S.; Schaffner, F.","year":"1960","unstructured":"Popper, H., Rubin, E., Krus, S., and Schaffner, F. (1960). Postnecrotic cirrhosis in alcoholics. Gastroenterology, 39, 669-686.","journal-title":"Gastroenterology"},{"key":"ref_16","first-page":"657","article-title":"Acute alcoholic hepatitis","volume":"46","author":"Porta, E.A.; Bergman, B.J.; Stein, A.A.","year":"1965","unstructured":"Porta, E. A., Bergman, B. J., and Stein, A. A. (1965). Acute alcoholic hepatitis. Amer. J. Path., 46, 657-690.","journal-title":"Amer. J. Path"},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"1257","DOI":"10.1177\/003591576706001205","article-title":"Primary biliary cirrhosis","volume":"60","author":"Scheuer, P.J.","year":"1967","unstructured":"Scheuer, P. J. (1967). Primary biliary cirrhosis. Proc. roy. Soc. Med., 60, 1257-1260.","journal-title":"Proc. roy. Soc. Med"},{"key":"ref_18","article-title":"Liver Biopsy Interpretation","author":"Scheuer, P.J.","year":"1968","unstructured":"Scheuer, P. J. (1968). Liver Biopsy Interpretation. Bailliere, Tindall Cassell, London."},{"key":"ref_19","article-title":"Diseases of the Liver and Biliary System","author":"Sherlock, S.","year":"1971","unstructured":"Sherlock, S. (1971). Diseases of the Liver and Biliary System, 4th ed. (revised 3rd printing). Blackwell, Oxford.","edition":"4th ed."},{"key":"ref_20","first-page":"107","article-title":"Infantile cirrhosis: an analytic review of the literature and a report of 50 cases","volume":"28","author":"Smetana, H.F.; Hadley, G.G.; Sirsat, S.M.","year":"1961","unstructured":"Smetana, H. F., Hadley, G. G., and Sirsat, S. M. (1961). Infantile cirrhosis: an analytic review of the literature and a report of 50 cases. 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