{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,6]],"date-time":"2025-12-06T04:52:40Z","timestamp":1764996760528,"version":"3.46.0"},"reference-count":16,"publisher":"BMJ","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Clin Pathol"],"published-print":{"date-parts":[[1974,1]]},"abstract":"<jats:p>\n                    The first commercial kit for the radioisotopic assay of vitamin B\n                    <jats:sub>12<\/jats:sub>\n                    in serum\u2014the Phadebas B\n                    <jats:sub>12<\/jats:sub>\n                    Test produced higher values than the radioisotopic method of Raven, Robson, Walker, and Barkham (1969) and the\n                    <jats:italic>Lactobacillus leichmannii<\/jats:italic>\n                    microbiological assay. Its normal range was 300-1100 pg\/ml and its reproducibility was similar to that of the other radioisotopic method. It should be possible to lower the results obtained by the Phadebas method by modifying its standard curve and to reduce the time taken for the assay by shortening its incubation period.\n                  <\/jats:p>","DOI":"10.1136\/jcp.27.1.59","type":"journal-article","created":{"date-parts":[[2007,6,9]],"date-time":"2007-06-09T00:50:46Z","timestamp":1181350246000},"page":"59-65","source":"Crossref","is-referenced-by-count":10,"title":["Experience with a commercial kit for the radioisotopic assay of vitamin B\n                    <sub>12<\/sub>\n                    in serum: the Phadebas B\n                    <sub>12<\/sub>\n                    Test"],"prefix":"10.1136","volume":"27","author":[{"given":"J. L.","family":"Raven","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M. B.","family":"Robson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[1974,1,1]]},"reference":[{"key":"ref_1","first-page":"421","article-title":"Addisonian pernicious anaemia and intrinsic factor antibodies in thyroid disorders","volume":"35","author":"Ardeman, S.; Chanarin, I.; Krafchik, B.; Singer, W.","year":"1966","unstructured":"Ardeman, S., Chanarin, I., Krafchik, B., and Singer, W. (1966). Addisonian pernicious anaemia and intrinsic factor antibodies in thyroid disorders. Quart. J. Med., 35, 421-431.","journal-title":"Quart. J. Med"},{"key":"ref_2","first-page":"130","article-title":"Hemoglobincoated charcoal radioassay for serum vitamin B12","volume":"28","author":"Herbert, V.; Gottlieb, C.W.; Lau, K.S.","year":"1966","unstructured":"Herbert, V., Gottlieb, C. W., and Lau, K. S. (1966). Hemoglobincoated charcoal radioassay for serum vitamin B12. 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(L.)","journal-title":"Blood"},{"key":"ref_10","article-title":"Radioisotopic assay of vitamin","author":"Raven, J.L.; Barkhan, P.","year":"1973","unstructured":"Raven, J. L., and Barkhan, P. (1973). Radioisotopic assay of vitamin"},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1111\/j.1365-2141.1972.tb08783.x","article-title":"Comparison of three methods for measuring vitamin B1, in serum: radioisotopic, Euglena gracilis and Lactobacillus leichmannii","volume":"22","author":"Raven, J.L.; Robson, M.B.; Morgan, J.O.; Hoffbrand, A.V.","year":"1972","unstructured":"Raven, J. L., Robson, M. B., Morgan, J. O., and Hoffbrand, A. V. (1972). Comparison of three methods for measuring vitamin B1, in serum: radioisotopic, Euglena gracilis and Lactobacillus leichmannii. Brit. J. Haemat., 22, 21-31.","journal-title":"Brit. J. Haemat"},{"key":"ref_12","first-page":"89","article-title":"The effect of cyanide, serum and other factors on the assay of vitamin B1, by a radio-isotope method using 17CoBl3, intrinsic factor and coated charcoal","volume":"117","author":"Raven, J.L.; Robson, M.B.; Walker, P.L.; Barkhan, P.","year":"1968","unstructured":"Raven, J. L., Robson, M. B., Walker, P. L., and Barkhan, P. (1968). The effect of cyanide, serum and other factors on the assay of vitamin B1, by a radio-isotope method using 17CoBl3, intrinsic factor and coated charcoal. Guy's Hosp. Rep., 117, 89-109.","journal-title":"Guy's Hosp. Rep"},{"year":"1969","author":"Raven, J.L.; Robson, M.B.; Walker, P.L.; Barkhan, P.","key":"ref_13","unstructured":"Raven, J. L., Robson, M. B., Walker, P. L., and Barkhan, P. 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Scand","volume":"27","author":"Wide, L.; Killander, A.","year":"1971","unstructured":"Wide, L., and Killander, A. (1971). A radiosorbent technique for the assay of serum vitamin B12. Scand. J. clin. Lab. Invest., 27 151-159.","journal-title":"J. clin. Lab. 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