{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,26]],"date-time":"2025-09-26T19:40:01Z","timestamp":1758915601383,"version":"3.44.0"},"reference-count":18,"publisher":"BMJ","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Clin Pathol"],"published-print":{"date-parts":[[1975,6]]},"abstract":"<jats:p>The primary necropsy finding are presented for 726 perinatal deaths; the classification of the 1958 British Perinatal Mortality Survey is used, and results of the two surveys are compared. Lethan malformation has replaced intrapartum hypoxia as the most common cause of perinatal death. There has been substantial reduction in intracranial trauma but an increase in intraventricular haemorrhage and, possible, extrapulmonary infection. Chromosome abnormalities occurred in 28 of 500 karyotyped infants (5-6 per cent). Indications for genetic counselling, and antenatal diagnosis in any subsequent pregnancy, were apparent in 10 per cent of cases.<\/jats:p>","DOI":"10.1136\/jcp.28.6.428","type":"journal-article","created":{"date-parts":[[2007,6,9]],"date-time":"2007-06-09T00:50:46Z","timestamp":1181350246000},"page":"428-434","source":"Crossref","is-referenced-by-count":38,"title":["A perinatal mortality survey in south-east London, 1970-73: the pathological findings in 726 necropsies."],"prefix":"10.1136","volume":"28","author":[{"given":"G A","family":"Machin","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[1975,6,1]]},"reference":[{"key":"ref_1","article-title":"PerinatalMortality: The First Report of the 1958 British Perinatal Survey","author":"Butler, N.R.; Bonham, D.G.","year":"1963","unstructured":"Butler, N. R. and Bonham, D. G. (1963). PerinatalMortality: The First Report of the 1958 British Perinatal Survey. Livingstone, Edinburgh."},{"key":"ref_2","article-title":"PerinatalProblems: The Second Report of the 1958 British Perinatal Mortality Survey","author":"Butler, N.R.; Alberman, E.D.","year":"1969","unstructured":"Butler, N. R. and Alberman, E. D. (1969). PerinatalProblems: The Second Report of the 1958 British Perinatal Mortality Survey. Livingstone, Edinburgh."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"1119","DOI":"10.1177\/003591577306601131","article-title":"Fetal abnormalities as cause of perinatal death","volume":"66","author":"Claireaux, A.E.","year":"1973","unstructured":"Claireaux, A. E. (1973). Fetal abnormalities as cause of perinatal death. Proc. roy. Soc. Med., 66, 1119-1120.","journal-title":"Proc. roy. Soc. Med"},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1093\/oxfordjournals.bmb.a070674","article-title":"Human population cytogenetics","volume":"25","author":"Court Brown, W.M.; Smith, P.G.","year":"1969","unstructured":"Court Brown, W. M. and Smith, P. G. (1969). Human population cytogenetics. Brit. med. Bull., 25, 74-80.","journal-title":"Brit. med. Bull"},{"key":"ref_5","article-title":"Social Security (1973). On the State ofthe","author":"Department of Health and","year":"1972","unstructured":"Department of Health and Social Security (1973). On the State ofthe Public Health, 1972. HMSO, London.","journal-title":"Public Health"},{"key":"ref_6","first-page":"140","article-title":"Perinatal mortality in Newcastle-upon-Tyne 1960-62","volume":"1","author":"Fairweather, D.V.I.; Russell, J.K.; Anderson, G.S.; Bird, T.; Millar, D.G.; Pearcy, P.A.M.","year":"1966","unstructured":"Fairweather, D. V. I., Russell, J. K., Anderson, G. S., Bird, T., Millar, D. G., and Pearcy, P. A. M. (1966). Perinatal mortality in Newcastle-upon-Tyne 1960-62. Lancet, 1, 140-142.","journal-title":"Lancet"},{"key":"ref_7","article-title":"Certain causes of neonatal death","author":"Fedrick, J.; Butler, N.R.","year":"1970","unstructured":"Fedrick, J. and Butler, N. R. (1970a). Certain causes of neonatal death."},{"key":"ref_8","first-page":"15","article-title":"Certain causes of neonatal death","year":"1970","unstructured":"Hyaline membranes. Biol. Neonat. (Basel), 15,229-255. Fedrick, J. and Butler, N. R. (1970b). Certain causes of neonatal death. II. Intraventricular haemorrhage. Biol. Neonat. (Basel), 15,257-290.","journal-title":"II. Intraventricular haemorrhage. Biol. Neonat. (Basel)"},{"key":"ref_9","first-page":"17","article-title":"Certain causes of neonatal death. III. Pulmonary infection (a) clinical factors","author":"Fedrick, J.; Butler, N.R.","year":"1971","unstructured":"Fedrick, J. and Butler, N. R. (1971a). Certain causes of neonatal death. III. Pulmonary infection (a) clinical factors. Biol. Neonat. (Basel), 17,458-471.","journal-title":"Biol. Neonat. (Basel)"},{"key":"ref_10","first-page":"45","article-title":"Certain causes of neonatal death","volume":"18","author":"Fedrick, J.; Butler, N.R.","year":"1971","unstructured":"Fedrick, J. and Butler, N. R. (1971b). Certain causes of neonatal death. III. Pulmonary infection (b) pregnancy and delivery. Biol. Neonat. (Basel), 18, 45-57.","journal-title":"III. Pulmonary infection (b) pregnancy and delivery. Biol. Neonat. (Basel)"},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1159\/000240366","article-title":"Certain causes of neonatal death. IV. Massive pulmonary haemorrhage","volume":"18","author":"Fedrick, J.; Butler, N.R.","year":"1971","unstructured":"Fedrick, J. and Butler, N. R. (1971c). Certain causes of neonatal death. IV. Massive pulmonary haemorrhage. Biol. Neonat. (Basel), 18, 243-262.","journal-title":"Biol. Neonat. (Basel)"},{"key":"ref_12","first-page":"109","article-title":"Diagnosis of the respiratory distress syndrome by amniocentesis","author":"Gluck, L.; Kulovich, M.V.; Borer, Jr., R.C.; Brenner, P.H.; Anderson, G.G.; Spellacy, W.N.","year":"1971","unstructured":"Gluck, L., Kulovich, M. V., Borer, R. C., Jr., Brenner, P. H., Anderson, G. G., and Spellacy, W. N. (1971). Diagnosis of the respiratory distress syndrome by amniocentesis. Amer. J. Obstet. Gynec., 109,440-445.","journal-title":"Amer. J. Obstet. Gynec"},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1093\/ajcp\/34.3.247","article-title":"Evaluation of body and organ weights in perinatal pathology. I. Normal standards derived from autopsies","volume":"34","author":"Gruenwald, P.; Minh, H.N.","year":"1960","unstructured":"Gruenwald, P. and Minh, H. N. (1960). Evaluation of body and organ weights in perinatal pathology. I. Normal standards derived from autopsies. Amer. J. clin. Path., 34, 247-253.","journal-title":"Amer. J. clin. Path"},{"key":"ref_14","first-page":"776","article-title":"Chromosome studies in a neonatal population","volume":"106","author":"Hamerton, J.L.; Ray, M.; Abbott, J.Williamson C.; Ducasse, G.C.","year":"1972","unstructured":"Hamerton, J. L., Ray, M., Abbott, J.. Williamson C., and Ducasse, G. C. (1972). Chromosome studies in a neonatal population. C.M.A.J., 106, 776-779."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1136\/jcp.24.2.159","article-title":"The perinatal postmortem examination","volume":"24","author":"Langley, F.A.","year":"1971","unstructured":"Langley, F. A. (1971). The perinatal postmortem examination. J. clin. Path., 24, 159-169.","journal-title":"J. clin. Path"},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1542\/peds.50.4.515","article-title":"A controlled trial of antepartum glucocorticoid treatment for prevention of the respiratory distress syndrome in premature infants","volume":"50","author":"Liggins, G.C.; Howie, R.N.","year":"1972","unstructured":"Liggins, G. C., and Howie, R. N. (1972). A controlled trial of antepartum glucocorticoid treatment for prevention of the respiratory distress syndrome in premature infants. Pediatrics, 50, 515-525.","journal-title":"Pediatrics"},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"549","DOI":"10.1016\/S0140-6736(74)92726-3","article-title":"Chromosome abnormality and perinatal death","volume":"1","author":"Machin, G.A.","year":"1974","unstructured":"Machin, G. A. (1974). Chromosome abnormality and perinatal death. Lancet, 1, 549-551.","journal-title":"Lancet"},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"851","DOI":"10.1056\/NEJM196904172801602","article-title":"Chromosome aberrations in 2159 consecutive newborn babies","volume":"280","author":"Sergovich, F.; Valentine, G.H.; Chen, A.T.L.; Kinch, R.A.H.; Smout, M.S.","year":"1969","unstructured":"Sergovich, F., Valentine, G. H., Chen, A. T. L., Kinch, R. A. H., and Smout, M. S. (1969). Chromosome aberrations in 2159 consecutive newborn babies. New. Engl. J. Med., 280, 851-855.","journal-title":"New. Engl. J. Med"}],"container-title":["Journal of Clinical Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/jcp.28.6.428","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,9,26]],"date-time":"2025-09-26T19:05:32Z","timestamp":1758913532000},"score":1,"resource":{"primary":{"URL":"https:\/\/jcp.bmj.com\/lookup\/doi\/10.1136\/jcp.28.6.428"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1975,6]]},"references-count":18,"journal-issue":{"issue":"6","published-online":{"date-parts":[[1975,6,1]]},"published-print":{"date-parts":[[1975,6]]}},"alternative-id":["10.1136\/jcp.28.6.428"],"URL":"https:\/\/doi.org\/10.1136\/jcp.28.6.428","relation":{},"ISSN":["0021-9746","1472-4146"],"issn-type":[{"type":"print","value":"0021-9746"},{"type":"electronic","value":"1472-4146"}],"subject":[],"published":{"date-parts":[[1975,6]]}}}