{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,27]],"date-time":"2025-09-27T22:18:09Z","timestamp":1759011489044,"version":"3.44.0"},"reference-count":6,"publisher":"BMJ","issue":"10","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Clin Pathol"],"published-print":{"date-parts":[[1976,10]]},"abstract":"<jats:p>Sera from 627 students entering Colleges of Education between 1969 and 1972 were tested for hepatitis B surface antigen and antibody. One was found positive for antigen, none for antibody. Six for 15 positive Hepanosticon results and two positive Hepatest results occurred in sera which also gave positive heterophil antibody tests indicative of current or recent EB virus infection. One of these six sera was still positive in the Hepanosticon test after one absorption, and one of two Hepatests gave no positive reaction with the control cells. Eleven of 14 sera from cases of infectious mononucleosis gave positive Hepanosticon results and two were still positive after one absorption. Seven were positive in the Hepatest and only three of these were positive with the control cells. The control tests in the Hepanosticon and Hepatest do not clearly identify all false positives due to Paul Bunnell antibody. It is suggested that when a positive result in a passive haemagglutination test can be removed by absorption or if positive after absorption cannot be confirmed by other tests for hepatitis Bs antigen, the patient from whom the serum specimen was taken should be investigated for indications of current EB virus infection.<\/jats:p>","DOI":"10.1136\/jcp.29.10.880","type":"journal-article","created":{"date-parts":[[2007,6,9]],"date-time":"2007-06-09T00:50:46Z","timestamp":1181350246000},"page":"880-883","source":"Crossref","is-referenced-by-count":1,"title":["Screening tests for hepatitis B antigen and antibody in two colleges of education and studies on the relationship between nonspecific positive antibody tests and EB virus infection."],"prefix":"10.1136","volume":"29","author":[{"given":"K G","family":"Ruparelia","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J M","family":"Edwards","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[1976,10,1]]},"reference":[{"key":"ref_1","first-page":"55","author":"Carter, R.L.","year":"1971","unstructured":"Carter, R. L., and Penman, H. G., eds. (1971). Infectious Mononucleosis, pp. 55-57. Blackwell, Oxford.","journal-title":"Infectious Mononucleosis"},{"issue":"345","key":"ref_2","article-title":"Hepanosticon in screening for HBsAg","volume":"1","author":"Chicot, D.; Wright, R.; Brotman, B.; Prince, A.M.","year":"1975","unstructured":"Chicot, D., Wright, R., Brotman, B., and Prince, A. M. (1975). Hepanosticon in screening for HBsAg. (Letter.) Lancet, 1,345.","journal-title":"(Letter.) Lancet"},{"key":"ref_3","article-title":"Todd-Sanford Clinical Diagnosis by Laboratory Methods","author":"Davidsohn, I.","year":"1969","unstructured":"Davidsohn, I., and Henry, J. B., eds. (1969). Todd-Sanford Clinical Diagnosis by Laboratory Methods, 14th edition. Saunders, Philadelphia.","edition":"14th edition"},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"647","DOI":"10.1136\/jcp.27.8.647","article-title":"Studies on the diagnostic value of an immunofluorescence test for EB virus-specific IgM","volume":"27","author":"Edwards, J.M.B.; McSwiggan, D.A.","year":"1974","unstructured":"Edwards, J. M. B. and McSwiggan, D. A. (1974). Studies on the diagnostic value of an immunofluorescence test for EB virus-specific IgM. J. clin. Path., 27, 647-651.","journal-title":"J. clin. Path"},{"key":"ref_5","first-page":"974","article-title":"Viral hepatitis and tests for the Australia (hepatitis associated) antigen and antibody","volume":"42","author":"Pesendorfer, F.; Krassnitzky, O.; Wewalka, F.G.","year":"1970","unstructured":"Pesendorfer, F., Krassnitzky, O., and Wewalka, F. G. (1970) Viral hepatitis and tests for the Australia (hepatitis associated) antigen and antibody. Bull. WId Hlth Org., 42, 974-975.","journal-title":"Bull. WId Hlth Org"},{"key":"ref_6","first-page":"\"97","article-title":"Asymptomatic infection with EB virus","volume":"27","author":"Sutton, R.N.P.; Marston, S.D.; Almond, E.J.P.; Reynolds, K.; Pounds, F.J.","year":"1974","unstructured":"Sutton, R. N. P., Marston, S. D., Almond, E. J. P., Reynolds, K. and Pounds, F. J. (1974). Asymptomatic infection with EB virus. J. clin. Path., 27, 97-100. University Health Physicians and Public Health Laboratory Service Laboratories, Joint Investigation (1971). Infectious mononucleosis and its relationship to EB virus antibody. Brit. med. J., 4, 643-646.","journal-title":"J. clin. Path; Infectious mononucleosis and its relationship to EB virus antibody"}],"container-title":["Journal of Clinical Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/jcp.29.10.880","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,9,25]],"date-time":"2025-09-25T08:59:00Z","timestamp":1758790740000},"score":1,"resource":{"primary":{"URL":"https:\/\/jcp.bmj.com\/lookup\/doi\/10.1136\/jcp.29.10.880"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1976,10]]},"references-count":6,"journal-issue":{"issue":"10","published-online":{"date-parts":[[1976,10,1]]},"published-print":{"date-parts":[[1976,10]]}},"alternative-id":["10.1136\/jcp.29.10.880"],"URL":"https:\/\/doi.org\/10.1136\/jcp.29.10.880","relation":{},"ISSN":["0021-9746","1472-4146"],"issn-type":[{"type":"print","value":"0021-9746"},{"type":"electronic","value":"1472-4146"}],"subject":[],"published":{"date-parts":[[1976,10]]}}}