{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,20]],"date-time":"2026-09-20T19:35:11Z","timestamp":1789932911949,"version":"4.0.1"},"reference-count":22,"publisher":"BMJ","issue":"10","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Clin Pathol"],"published-print":{"date-parts":[[1976,10]]},"abstract":"<jats:p>Plasma fibrinogen concentration and whole-blood viscosity, the latter measured at two shear rates (23 and 230 sec-1), were estimated during eight episodes of sickle-cell crisis and compared with values in 26 sickle-cell anaemia patients who were not in crisis. Painful crisis was associated with a significant increase in both plasma fibrinogen and whole-blood viscosity. Increased fibrinogen-erythrocyte interaction in vivo may be a significant contributory factor to raising blood viscosity and precipitating vaso-occlusive crisis in sickle-cell disease.<\/jats:p>","DOI":"10.1136\/jcp.29.10.890","type":"journal-article","created":{"date-parts":[[2007,6,9]],"date-time":"2007-06-09T00:50:46Z","timestamp":1181350246000},"page":"890-893","source":"Crossref","is-referenced-by-count":18,"title":["Hyperfibrinogenaemia and hyperviscosity in sickle-cell crisis."],"prefix":"10.1136","volume":"29","author":[{"given":"S G","family":"Richardson","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G R","family":"Breeze","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J","family":"Stuart","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[1976,10,1]]},"reference":[{"key":"ref_1","author":"Amjad, H.; Bannerman, R.M.; Judisch, J.M.","year":"1974","unstructured":"Amjad, H., Bannerman, R. 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Stuttgart."}],"container-title":["Journal of Clinical Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/jcp.29.10.890","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,12,14]],"date-time":"2025-12-14T15:02:20Z","timestamp":1765724540000},"score":1,"resource":{"primary":{"URL":"https:\/\/jcp.bmj.com\/lookup\/doi\/10.1136\/jcp.29.10.890"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1976,10]]},"references-count":22,"journal-issue":{"issue":"10","published-online":{"date-parts":[[1976,10,1]]},"published-print":{"date-parts":[[1976,10]]}},"alternative-id":["10.1136\/jcp.29.10.890"],"URL":"https:\/\/doi.org\/10.1136\/jcp.29.10.890","relation":{},"ISSN":["0021-9746","1472-4146"],"issn-type":[{"value":"0021-9746","type":"print"},{"value":"1472-4146","type":"electronic"}],"subject":[],"published":{"date-parts":[[1976,10]]}}}