{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,29]],"date-time":"2025-10-29T19:08:39Z","timestamp":1761764919570,"version":"3.44.0"},"reference-count":7,"publisher":"BMJ","issue":"11","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Clin Pathol"],"published-print":{"date-parts":[[1977,11]]},"abstract":"<jats:p>This report describes a case of Laurence-Moon-Biedl syndrome identified in a 24-month-old boy. Significant renal involvement was present with right-sided vesicoureteral reflux, cystocele, urinary tract infections, and growth arrest of the right kidney. After the development of hypertension a left renal biopsy was performed to determine if bilateral renal disease was present. Histopathological and ultrastructural changes in the left kidney are described. These changes appear to be unrelated to pyelonephritis or hypertension and to be most consistent with the nephropathy of Laurence-Moon-Biedl syndrome.<\/jats:p>","DOI":"10.1136\/jcp.30.11.1077","type":"journal-article","created":{"date-parts":[[2007,6,9]],"date-time":"2007-06-09T00:50:46Z","timestamp":1181350246000},"page":"1077-1081","source":"Crossref","is-referenced-by-count":13,"title":["Renal histopathological changes in a child with Laurence-Moon-Biedl syndrome."],"prefix":"10.1136","volume":"30","author":[{"given":"B","family":"Falkner","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C","family":"Langman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S","family":"Katz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[1977,11,1]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"254","DOI":"10.1038\/ki.1975.37","article-title":"Ultrastructure of glomerulat disease: A review","volume":"7","author":"Churg, J.; Grishman, E.","year":"1975","unstructured":"Churg, J., and Grishman, E. (1975). Ultrastructure of glomerulat disease: A review. Kidney International, 7, 254-270.","journal-title":"Kidney International"},{"key":"ref_2","first-page":"206","article-title":"The renal lesion of the Laurence-MoonBiedl Syndrome","volume":"87","author":"Hurley, R.M.; Dery, P.; Nogrady, M.B.; Drummond, K.N.","year":"1975","unstructured":"Hurley, R. M., Dery, P., Nogrady, M. B., and Drummond, K. N. (1975). The renal lesion of the Laurence-MoonBiedl Syndrome. Journal ofPediatrics, 87, 206-209.","journal-title":"Journal ofPediatrics"},{"key":"ref_3","first-page":"347","article-title":"Histological changes in the renal glomerulus in essential (primary) hypertension","volume":"6","author":"McGregor, L.","year":"1930","unstructured":"McGregor, L. (1930). Histological changes in the renal glomerulus in essential (primary) hypertension. American Journal ofPathology, 6, 347-366.","journal-title":"American Journal ofPathology"},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1002\/path.1700930106","article-title":"Pathology of Laurence-Moon-Bardet-Biedl Syndrome","volume":"93","author":"McLoughlin, T.G.; Shanklin, D.R.","year":"1967","unstructured":"McLoughlin, T. G., and Shanklin, D. R. (1967). Pathology of Laurence-Moon-Bardet-Biedl Syndrome. Journal of Pathology and Bacteriology, 93, 65-79.","journal-title":"Journal of Pathology and Bacteriology"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"812","DOI":"10.1177\/000992287501400904","article-title":"The Laurence-Moon-Biedl Syndrome","volume":"14","author":"Moini, A.R.; Emamy, H.; Asadian, A.","year":"1975","unstructured":"Moini, A. R., Emamy, H., and Asadian, A. (1975). The Laurence-Moon-Biedl Syndrome. Clinical Pediatrics, 14, 812-815.","journal-title":"Clinical Pediatrics"},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"352","DOI":"10.1001\/archpedi.1969.02100030354022","article-title":"Laurence-Moon-Biedl Syndrome associated with multiple genito urinary tract anomalies","volume":"117","author":"Nadjmi, B.; Flanagan, M.J.; Christian, J.R.","year":"1969","unstructured":"Nadjmi, B., Flanagan, M. J., and Christian, J. R. (1969). Laurence-Moon-Biedl Syndrome associated with multiple genito urinary tract anomalies. American Journal of Diseases of Children, 117, 352-356.","journal-title":"American Journal of Diseases of Children"},{"key":"ref_7","first-page":"685","article-title":"Histologic studies of kidney biopsy specimens from patients with hypertension","volume":"34","author":"Sommers, S.C.; Relman, A.S.; Smithwick, R.H.","year":"1958","unstructured":"Sommers, S. C., Relman, A. S., and Smithwick, R. H. (1958). Histologic studies of kidney biopsy specimens from patients with hypertension. American Jouirnal of Pathology, 34, 685-716.","journal-title":"American Jouirnal of Pathology"}],"container-title":["Journal of Clinical Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/jcp.30.11.1077","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,9,25]],"date-time":"2025-09-25T12:55:55Z","timestamp":1758804955000},"score":1,"resource":{"primary":{"URL":"https:\/\/jcp.bmj.com\/lookup\/doi\/10.1136\/jcp.30.11.1077"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1977,11]]},"references-count":7,"journal-issue":{"issue":"11","published-online":{"date-parts":[[1977,11,1]]},"published-print":{"date-parts":[[1977,11]]}},"alternative-id":["10.1136\/jcp.30.11.1077"],"URL":"https:\/\/doi.org\/10.1136\/jcp.30.11.1077","relation":{},"ISSN":["0021-9746","1472-4146"],"issn-type":[{"type":"print","value":"0021-9746"},{"type":"electronic","value":"1472-4146"}],"subject":[],"published":{"date-parts":[[1977,11]]}}}