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The histochemical method was considered to be the most practical for laboratories handling small numbers of biopsies but the biochemical estimation of acetylcholinesterase activity was found to be a useful complementary procedure and an accurate quantitative assessment of enzyme activity.<\/jats:p>","DOI":"10.1136\/jcp.33.4.336","type":"journal-article","created":{"date-parts":[[2007,6,9]],"date-time":"2007-06-09T00:50:46Z","timestamp":1181350246000},"page":"336-343","source":"Crossref","is-referenced-by-count":28,"title":["Histochemical diagnosis of Hirschsprung's disease and a comparison of the histochemical and biochemical activity of acetylcholinesterase in rectal mucosal biopsies."],"prefix":"10.1136","volume":"33","author":[{"given":"W J","family":"Patrick","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G T","family":"Besley","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"I I","family":"Smith","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[1980,4,1]]},"reference":[{"key":"ref_1","first-page":"617","article-title":"A histochemical method for localising cholinesterase activity","volume-title":"Proc Soc Exp Biol Med 1949","volume":"70","author":"Koelle, G.B.; Friedenwald, J.S.","unstructured":"Koelle GB, Friedenwald JS. 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