{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,21]],"date-time":"2025-11-21T18:27:22Z","timestamp":1763749642797,"version":"3.45.0"},"reference-count":14,"publisher":"BMJ","issue":"9","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Clin Pathol"],"published-print":{"date-parts":[[1980,9]]},"abstract":"<jats:p>A four-year prospective study of endoscopic cytology and histology was carried out on 64 patients suspected of having a malignant lesion at the junction of the lower oesophagus and cardia. The final diagnosis was malignant in 18 and benign in 46 cases. Biopsy touch smear cytology was the most accurate technique with a sensitivity of 100% compared with 82% for brush cytology and 89% for biopsy histology. There was one false positive endoscopic histology report, but no false positive cytology result. Biopsy touch smear cytology is at present a method little used in the digestive tract. This study demonstrates its value in the diagnostically difficult area of the gastro-oesophageal junction.<\/jats:p>","DOI":"10.1136\/jcp.33.9.811","type":"journal-article","created":{"date-parts":[[2007,6,9]],"date-time":"2007-06-09T00:50:46Z","timestamp":1181350246000},"page":"811-814","source":"Crossref","is-referenced-by-count":24,"title":["Evaluation of endoscopic brush and biopsy touch smear cytology and biopsy histology in the diagnosis of carcinoma of the lower oesophagus and cardia."],"prefix":"10.1136","volume":"33","author":[{"given":"J A","family":"Young","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H E","family":"Hughes","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F D","family":"Lee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[1980,9,1]]},"reference":[{"key":"ref_1","first-page":"399","article-title":"Direct vision endoscopic cytology and biopsy in the diagnosis of esophageal and gastric tumors","volume":"21","author":"Prolla, J.C.; Reilly, R.W.; Kirsner, J.B.; Cockerham, L.","year":"1977","unstructured":"Prolla JC, Reilly RW, Kirsner JB, Cockerham L. Direct vision endoscopic cytology and biopsy in the diagnosis of esophageal and gastric tumors. Acta Cytol 1977;21: 399-402.","journal-title":"Acta Cytol"},{"key":"ref_2","first-page":"327","article-title":"Endoscopic cytology of the esophagus, stomach and pancreas","volume":"22","author":"Kasugai, T.; Kobayashi, S.; Kuno, N.","year":"1978","unstructured":"Kasugai T, Kobayashi S, Kuno N. Endoscopic cytology of the esophagus, stomach and pancreas. Acta Cytol 1978;22:327-30.","journal-title":"Acta Cytol"},{"key":"ref_3","first-page":"296","article-title":"Cytology in the diagnosis of oesophageal cancer","volume":"1","author":"Hishon, S.; Lovell, D.; Gummer, J.W.P.; Smithies, A.; Shawdon, H.; Blendis, L.M.","year":"1976","unstructured":"Hishon S, Lovell D, Gummer JWP, Smithies A, Shawdon H, Blendis LM. Cytology in the diagnosis of oesophageal cancer. Lancet 1976;1:296-7.","journal-title":"Lancet"},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"246","DOI":"10.1002\/bjs.1800660408","article-title":"Comparison of brush cytology before and after biopsy for diagnosis of gastric carcinoma","volume":"66","author":"Keighley, M.R.B.; Thompson, H.; Moore, J.; Hoare, A.M.; Allen, R.N.; Dykes, P.W.","year":"1979","unstructured":"Keighley MRB, Thompson H, Moore J, Hoare AM, Allen RN, Dykes PW. Comparison of brush cytology before and after biopsy for diagnosis of gastric carcinoma. Br J Surg 1979;66:246-7.","journal-title":"Br J Surg"},{"article-title":"Report of a three year trial of endoscopic cytology of the stomach and duodenum","author":"Young, J.A.; Hughes, H.E.","key":"ref_5","unstructured":"Young JA, Hughes HE. Report of a three year trial of endoscopic cytology of the stomach and duodenum. Gut (in press)."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"440","DOI":"10.1002\/1097-0142(197601)37:1+<440::AID-CNCR2820370708>3.0.CO;2-T","article-title":"The role of upper gastrointestinal endoscopy in patients with cancer","volume":"37","author":"Winawer, S.J.; Sherlock, P.; Hajdu, S.I.","year":"1976","unstructured":"Winawer SJ, Sherlock P, Hajdu SI. The role of upper gastrointestinal endoscopy in patients with cancer. Cancer 1976;37:440-8.","journal-title":"Cancer"},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1136\/gut.17.5.375","article-title":"Evaluation of specific value of endoscopic biopsies and brush cytology for malignancies of the oesophagus and stomach","volume":"17","author":"Witzel, L.; Halter, F.; Gretillat, P.A.; Scheurer, U.; Keller, M.","year":"1976","unstructured":"Witzel L, Halter F, Gretillat PA, Scheurer U, Keller M. Evaluation of specific value of endoscopic biopsies and brush cytology for malignancies of the oesophagus and stomach. Gut 1976;17:375-7.","journal-title":"Gut"},{"key":"ref_8","first-page":"367","article-title":"Carcinoma of the oesophagus and cardia; diagnostic evaluation in 113 cases","volume":"70","author":"Bruni, H.C.; Nelson, R.S.","year":"1975","unstructured":"Bruni HC, Nelson RS. Carcinoma of the oesophagus and cardia; diagnostic evaluation in 113 cases. J Thorac Cardiovasc Surg 1975;70:367-70.","journal-title":"J Thorac Cardiovasc Surg"},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1016\/S0300-5089(21)00407-7","article-title":"Endoscopy, cytology and biopsy in the upper gastrointestinal tract","volume":"7","author":"Hughes, H.E.; Lee, F.D.; MacKenzie, J.F.","year":"1978","unstructured":"Hughes HE, Lee FD, MacKenzie JF. Endoscopy, cytology and biopsy in the upper gastrointestinal tract. Clin Gastroenterol 1978;7:375-96.","journal-title":"Clin Gastroenterol"},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1093\/oxfordjournals.bmb.a070810","article-title":"Validation of screening procedures","volume":"27","author":"Cochrane, A.L.; Holland, W.W.","year":"1971","unstructured":"Cochrane AL, Holland WW. Validation of screening procedures. Br Med Bull 1971;27:3-8.","journal-title":"Br Med Bull"},{"key":"ref_11","first-page":"249","article-title":"Significance of imprint smears in cytologic diagnosis of malignant tumours of the stomach","volume":"14","author":"Yoshii, Y.; Takahashi, J.; Yamaoka, Y.; Kasugai, T.","year":"1970","unstructured":"Yoshii Y, Takahashi J, Yamaoka Y, Kasugai T. Significance of imprint smears in cytologic diagnosis of malignant tumours of the stomach. Acta Cytol 1970;14: 249-53","journal-title":"Acta Cytol"},{"key":"ref_12","first-page":"164","article-title":"The correlation of target biopsy and contact smear cytology under direct visual control in malignant gastric lesions","volume":"17","author":"Yamakawa, I.; Parish, J.; Berci, G.","year":"1971","unstructured":"Yamakawa I, Parish J, Berci G, et al. The correlation of target biopsy and contact smear cytology under direct visual control in malignant gastric lesions. Gastrointest Endosc 1971;17:164-8.","journal-title":"Gastrointest Endosc"},{"key":"ref_13","first-page":"463","article-title":"Touch smear cytology for endoscopic diagnosis of gastric carcinoma","volume":"67","year":"1977","unstructured":"Tamura K, Masuzawa M, Akiyama T, Fukui 0. Touch smear cytology for endoscopic diagnosis of gastric carcinoma. Am J Gastroenterol 1977;67:463-7.","journal-title":"Am J Gastroenterol"},{"key":"ref_14","article-title":"Cancer: Diagnosis, Treatment and Prognosis","author":"Ackerman, L.V.; Del Regato, J.A.","year":"1970","unstructured":"Ackerman LV, Del Regato JA. Cancer: Diagnosis, Treatment and Prognosis. 4th ed. St Louis: Mosby, 1970.","edition":"4th ed"}],"container-title":["Journal of Clinical Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/jcp.33.9.811","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,11,21]],"date-time":"2025-11-21T18:13:25Z","timestamp":1763748805000},"score":1,"resource":{"primary":{"URL":"https:\/\/jcp.bmj.com\/lookup\/doi\/10.1136\/jcp.33.9.811"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1980,9]]},"references-count":14,"journal-issue":{"issue":"9","published-online":{"date-parts":[[1980,9,1]]},"published-print":{"date-parts":[[1980,9]]}},"alternative-id":["10.1136\/jcp.33.9.811"],"URL":"https:\/\/doi.org\/10.1136\/jcp.33.9.811","relation":{},"ISSN":["0021-9746","1472-4146"],"issn-type":[{"type":"print","value":"0021-9746"},{"type":"electronic","value":"1472-4146"}],"subject":[],"published":{"date-parts":[[1980,9]]}}}