{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,14]],"date-time":"2025-12-14T06:55:22Z","timestamp":1765695322540,"version":"3.48.0"},"reference-count":13,"publisher":"BMJ","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Clin Pathol"],"published-print":{"date-parts":[[1981,3]]},"abstract":"<jats:p>Bloodstream infection is demonstrable at necropsy in 21.1% of perinatal death but is almost invariably a secondary event, often terminal, contributing to death as a secondary cause. In only 3.8% is infection recorded as the primary cause of death. Escherichia coli predominates, and postmortem and antemortem studies alike confirm the tendency of this and other microbes to involve the meninges in the course of bloodstream infection. Fatal viral and fungal infections are rare, and life-threatening disease is overwhelmingly of bacterial origin. A separate, prospective study of septicaemia in the newborn is reported, and the data are tabulated. The overall incidence in inborn and outborn populations, together with the incidence of specific infections, is stated, and the relationship to birthweight is analysed. The overall mortality for treated cases is 40.7% the mortality being inversely proportional to birthweight, and highest at 62.5% in those born weighting less than 1000 g. The advent of meningitis (1 in 5 cases of septicaemia) aggravates the mortality (83%). The potential hazard of nursing seriously infected babies is emphasised.<\/jats:p>","DOI":"10.1136\/jcp.34.3.271","type":"journal-article","created":{"date-parts":[[2007,6,9]],"date-time":"2007-06-09T00:50:46Z","timestamp":1181350246000},"page":"271-276","source":"Crossref","is-referenced-by-count":11,"title":["Bloodstream infections and perinatal mortality."],"prefix":"10.1136","volume":"34","author":[{"given":"R","family":"Hurley","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J","family":"de Louvois","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[1981,3,1]]},"reference":[{"key":"ref_1","first-page":"747","article-title":"Bacterial infections","volume-title":"diseases of the fetus and newborn","author":"Klein, J.O.; Marcy, S.M.","year":"1976","unstructured":"Klein JO, Marcy SM. Bacterial infections. In: Remington JS, Klein JO, eds. Infectious diseases of the fetus and newborn. Philadelphia, London and Toronto: WB Saunders, 1976:747-802."},{"key":"ref_2","first-page":"306","article-title":"Infection of the fetus and newborn in contemporary obstetrics and gynaecology","author":"A, Davies Pamela","year":"1977","unstructured":"Davies Pamela A. Infection of the fetus and newborn in contemporary obstetrics and gynaecology. Chamberlain GVP, ed. London: Northwood Publications Limited, 1977:306-315."},{"key":"ref_3","first-page":"1","article-title":"An introduction to infections of the fetus and newborn infant","volume-title":"Infectious diseases of the fetus and newborn. Philadelphia, London and","author":"Klein, J.O.; Remington, J.S.; Marcy, S.M.","year":"1976","unstructured":"Klein JO, Remington JS, Marcy SM. An introduction to infections of the fetus and newborn infant. In: Remington JS, Klein JO, eds. Infectious diseases of the fetus and newborn. Philadelphia, London and Toronto: WB Saunders, 1976:1-32."},{"key":"ref_4","first-page":"1045","article-title":"Faecal carriage of Pseudomonas aeruginosa by k newborn babies","volume":"ii:","year":"1970","unstructured":"Cooke E Mary, Shooter RA, O'Farrell Shelia M, Martin * Diana R. Faecal carriage of Pseudomonas aeruginosa by k newborn babies. Lancet 1970;ii:1045-6.","journal-title":"Lancet"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1099\/00222615-12-2-201","article-title":"Acquisition of Klebsiella aerogenes by neonates","volume":"12","author":"Ruth, Shinebaum; Mary, Cooke E.; C, Brayson Janet","year":"1979","unstructured":"Shinebaum Ruth, Cooke E Mary, Brayson Janet C. Acquisition of Klebsiella aerogenes by neonates. 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J Antimicrob Chemother 1979; vol. 5, Suppl A. 27-37.","journal-title":"J Antimicrob Chemother; neonatal infections"},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1016\/S0022-3476(70)80148-2","article-title":"Neonatal septicaemia","volume":"76","author":"Gotoff, S.P.; Behrmann, R.E.","year":"1970","unstructured":"Gotoff SP, Behrmann RE. Neonatal septicaemia. J Pediat 1970;76:142-53.","journal-title":"J Pediat"},{"key":"ref_11","doi-asserted-by":"crossref","DOI":"10.1093\/jac\/5.Supplement_A.59","article-title":"Infections and perinatal mortality","volume":"vol.","author":"Pryse-Davies, J.; Rosalinde, Hurley","year":"1979","unstructured":"Pryse-Davies J, Hurley Rosalinde. Infections and perinatal mortality. In: Hurley Rosalinde, de Louvois J, Drasar Fiona, eds. Perinatal and neonatal infections. J Antimicrob Chemother 1979; vol.","journal-title":"J Antimicrob Chemother; neonatal infections"},{"key":"ref_12","article-title":"Serious infections in obstetric and neonatal practice","author":"Rosalinde, Hurley; de Louvois J","unstructured":"Hurley Rosalinde, de Louvois J. Serious infections in obstetric and neonatal practice. J Royal Soc Med in press.","journal-title":"J Royal Soc Med"},{"key":"ref_13","first-page":"639","article-title":"Survival of preterm babies","volume":"ii:","year":"1980","unstructured":"Starte DR, Jones RAK, Hall MA, Harvey DR. Survival of preterm babies. Lancet 1980;ii:639-40.","journal-title":"Lancet"}],"container-title":["Journal of Clinical Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/jcp.34.3.271","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,12,14]],"date-time":"2025-12-14T06:51:37Z","timestamp":1765695097000},"score":1,"resource":{"primary":{"URL":"https:\/\/jcp.bmj.com\/lookup\/doi\/10.1136\/jcp.34.3.271"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1981,3]]},"references-count":13,"journal-issue":{"issue":"3","published-online":{"date-parts":[[1981,3,1]]},"published-print":{"date-parts":[[1981,3]]}},"alternative-id":["10.1136\/jcp.34.3.271"],"URL":"https:\/\/doi.org\/10.1136\/jcp.34.3.271","relation":{},"ISSN":["0021-9746","1472-4146"],"issn-type":[{"type":"print","value":"0021-9746"},{"type":"electronic","value":"1472-4146"}],"subject":[],"published":{"date-parts":[[1981,3]]}}}