{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,13]],"date-time":"2025-12-13T04:13:16Z","timestamp":1765599196662,"version":"3.48.0"},"reference-count":16,"publisher":"BMJ","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Clin Pathol"],"published-print":{"date-parts":[[1981,4]]},"abstract":"<jats:p>Fifty-six blood donor sera were examined by indirect immunofluorescence for IgG antibodies to a selection of anaerobic bacterial strains, often isolated from wound cultures. Another 25 sera were examined by IgG antibodies to six NCTC Bacteroides strains. A wide range of IgG antibody titres were found against Fusobacterium, Clostridium, and anaerobic streptococcal species. Very low titres were found against the Bacteroides strains. It is suggested that the testing of a single serum specimen for IgG antibodies against a representative collection of Bacteroides fragilis strains could be helpful in verifying a clinical suspicion of infection with these organisms.<\/jats:p>","DOI":"10.1136\/jcp.34.4.416","type":"journal-article","created":{"date-parts":[[2007,6,9]],"date-time":"2007-06-09T00:50:46Z","timestamp":1181350246000},"page":"416-419","source":"Crossref","is-referenced-by-count":4,"title":["IgG antibodies against anaerobic bacteria in blood donor sera."],"prefix":"10.1136","volume":"34","author":[{"given":"A","family":"Schwan","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[1981,4,1]]},"reference":[{"key":"ref_1","first-page":"709","article-title":"The immune response in a patient to an infection with Bacteroides fragilis ss fragilis and Clostridium difficile","volume":"80","author":"Danielsson, D.; Lambe, D.W.; Persson, S.","year":"1972","unstructured":"Danielsson D, Lambe DW, Persson S. The immune response in a patient to an infection with Bacteroides fragilis ss fragilis and Clostridium difficile. Acta Pathol Microbiol Scand section B 1972;80:709-12.","journal-title":"Acta Pathol Microbiol Scand section B"},{"key":"ref_2","first-page":"52","article-title":"Investigation of the immune response to aerobic and anaerobic intestinal bacteria in a patient with Crohn's disease","volume":"19","year":"1979","unstructured":"Investigation of the immune response to aerobic and anaerobic intestinal bacteria in a patient with Crohn's disease. ScandJInfect Dis 1979; suppl. 19:52-60.","journal-title":"ScandJInfect Dis"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1093\/infdis\/131.5.499","article-title":"Immune response in eight patients infected with Bacteroidesfragilis","volume":"131","author":"Lambe, D.W.; Danielsson, D.; Vroon, D.H.; Carver, R.K.","year":"1975","unstructured":"Lambe DW, Danielsson D, Vroon DH, Carver RK. Immune response in eight patients infected with Bacteroidesfragilis. JInfect Dis 1975;131:499-508.","journal-title":"JInfect Dis"},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1093\/infdis\/130.1.70","article-title":"Detection of Bacteroides fragilis infection by precipitin antibody","volume":"130","author":"Rissing, J.P.; Crowder, J.G.; Smith, J.W.; White, A.","year":"1974","unstructured":"Rissing JP, Crowder JG, Smith JW, White A. Detection of Bacteroides fragilis infection by precipitin antibody. J Infect Dis 1974;130:70-3.","journal-title":"J Infect Dis"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"213","DOI":"10.3109\/inf.1978.10.issue-3.10","article-title":"Antibody response in thirteen patients with Bacteroides fragilis infections","volume":"10","author":"Schwan, A.; Ryden, A.-C.","year":"1978","unstructured":"Schwan A, Ryden A-C. Antibody response in thirteen patients with Bacteroides fragilis infections. Scand J Infect Dis 1978;10:213-8.","journal-title":"Scand J Infect Dis"},{"key":"ref_6","first-page":"173","article-title":"Immune response to anaerobic infections","volume-title":"Anaerobic bacteria. Role in disease","author":"Danielsson, D.; Lambe, D.W.; Persson, S.","year":"1974","unstructured":"Danielsson D, Lambe DW, Persson S. Immune response to anaerobic infections. In: Balows A, Dehaan RM, Dowell VR, Guze LB, eds. Anaerobic bacteria. Role in disease. Springfield, Ill: Charles C Thomas, 1974;173-91."},{"key":"ref_7","first-page":"61","article-title":"Infection of total hip prostheses by Peptococcus magnus: an immunofluorescence and ELISA study of two cases","volume":"32","author":"Taylor, A.G.; Fincham, W.J.; Golding, M.A.; Cook, J.","year":"1979","unstructured":"Taylor AG, Fincham WJ, Golding MA, Cook J. Infection of total hip prostheses by Peptococcus magnus: an immunofluorescence and ELISA study of two cases. J ClinPathol 1979;32:61-5.","journal-title":"J ClinPathol"},{"issue":"1","key":"ref_8","first-page":"19","article-title":"The clinical importance of anaerobic bacteria in wound infections after gastrointestinal surgery","volume":"10","author":"Schwan, A.; Ryden, A.-C.","year":"1978","unstructured":"Schwan A, Ryden A-C. The clinical importance of anaerobic bacteria in wound infections after gastrointestinal surgery. ScandJInfect Dis 1978;10:1 19-25.","journal-title":"ScandJInfect Dis"},{"key":"ref_9","first-page":"61","article-title":"On the occurrence of serum antibodies to Bacteroides fragilis and serogroups of E. coli in patients with Crohn's disease","volume":"19","author":"Persson, S.; Danielsson, D.","year":"1979","unstructured":"Persson S, Danielsson D. On the occurrence of serum antibodies to Bacteroides fragilis and serogroups of E. coli in patients with Crohn's disease. Scand J Infect Dis 1979;suppl. 19:61-7.","journal-title":"Scand J Infect Dis"},{"key":"ref_10","first-page":"994","article-title":"Distribution of a group reactive antigen among some bacteria and occurrence of antibodies in human sera to this antigen. Acta Pathol Microbiol Scand 1969; 77: 717-26. 12 Rissing JP, Buxton TB, Edmondson HT. Detection of specific IgG antibody in sera from patients infected with Bacteroides fragilis by enzyme-linked immunosorbent assay","volume":"140","year":"1979","unstructured":"Distribution of a group reactive antigen among some bacteria and occurrence of antibodies in human sera to this antigen. Acta Pathol Microbiol Scand 1969;77:717-26. 12 Rissing JP, Buxton TB, Edmondson HT. Detection of specific IgG antibody in sera from patients infected with Bacteroides fragilis by enzyme-linked immunosorbent assay. J Infect Dis 1979;140:994-8.","journal-title":"J Infect Dis"},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1093\/infdis\/129.3.349","article-title":"Antibodies reacting with lipopolysaccharides from Bacteroides melaninogenicus, Bacteroides fragilis, and Fusobacterium nucleatum in serum from normal subjects","volume":"129","author":"Hofstad, T.","year":"1974","unstructured":"Hofstad T. Antibodies reacting with lipopolysaccharides from Bacteroides melaninogenicus, Bacteroides fragilis, and Fusobacterium nucleatum in serum from normal subjects. J Infect Dis 1974;129:349-52.","journal-title":"J Infect Dis"},{"key":"ref_12","article-title":"Anaerobe laboratory manual","author":"Holdeman, L.V.; Cato, E.P.; Moore, W.E.C.","year":"1977","unstructured":"Holdeman LV, Cato EP, Moore WEC. Anaerobe laboratory manual. Blacksburg, Va: Virginia Polytechnic Institute and State University, 1977."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"1351","DOI":"10.1093\/ajcn\/25.12.1351","article-title":"Human antibody to Bacteroidaceae","volume":"25","author":"Quick, J.D.; Goldberg, H.S.; Sonnenwirth, A.C.","year":"1972","unstructured":"Quick JD, Goldberg HS, Sonnenwirth AC. Human antibody to Bacteroidaceae. Am J Clin Nutr 1972;25:1351-6.","journal-title":"Am J Clin Nutr"},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"112","DOI":"10.4049\/jimmunol.97.1.112","article-title":"Bactericidal antibody in mammalian serum to obligatory anaerobic gram negative bacteria","volume":"97","author":"Evans, R.T.; Spaeth, S.; Mergenhagen, S.E.","year":"1966","unstructured":"Evans RT, Spaeth S, Mergenhagen SE. Bactericidal antibody in mammalian serum to obligatory anaerobic gram negative bacteria. JImmunol 1966;97:112-9.","journal-title":"JImmunol"},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1017\/S0022172400053791","article-title":"The distribution of Bacteroides fragilis serotypes amongst clinical strains","volume":"81","author":"Elhag, K.M.; Tabaqchali, S.","year":"1978","unstructured":"Elhag KM, Tabaqchali S. The distribution of Bacteroides fragilis serotypes amongst clinical strains. J Hyg Camb 1978;81:89-97.","journal-title":"J Hyg Camb"},{"key":"ref_16","article-title":"The pathogenic anaerobic bacteria","author":"Smith, L.D.","year":"1975","unstructured":"Smith LD. The pathogenic anaerobic bacteria. Springfield, Ill: Charles C Thomas, 1975;153."}],"container-title":["Journal of Clinical Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/jcp.34.4.416","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,12,13]],"date-time":"2025-12-13T04:09:42Z","timestamp":1765598982000},"score":1,"resource":{"primary":{"URL":"https:\/\/jcp.bmj.com\/lookup\/doi\/10.1136\/jcp.34.4.416"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1981,4]]},"references-count":16,"journal-issue":{"issue":"4","published-online":{"date-parts":[[1981,4,1]]},"published-print":{"date-parts":[[1981,4]]}},"alternative-id":["10.1136\/jcp.34.4.416"],"URL":"https:\/\/doi.org\/10.1136\/jcp.34.4.416","relation":{},"ISSN":["0021-9746","1472-4146"],"issn-type":[{"type":"print","value":"0021-9746"},{"type":"electronic","value":"1472-4146"}],"subject":[],"published":{"date-parts":[[1981,4]]}}}