{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,6]],"date-time":"2025-12-06T04:53:11Z","timestamp":1764996791130,"version":"3.46.0"},"reference-count":17,"publisher":"BMJ","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Clin Pathol"],"published-print":{"date-parts":[[1981,6]]},"abstract":"<jats:p>The prevalence of antibody against Toxoplasma gondi in a population of 715 pregnant women has been evaluated by two methods: indirect haemagglutination antibody (IHA) and indirect fluorescent antibody (IFA) test and all positive sera were checked by the dye test. Five hundred of the study population were questioned on diet and on animal contact to elucidate a possible relation to the prevalence of antibody. Results are expressed in international units (IU) of antibody against T gondi. Of the 715 sera, 171 were positive by IHA and 173 by IFA. One hundred and sixty-seven sera were positive by both tests, ninety-eight (58%) correlating exactly, as to the concentration of antibody. The ten sera which were not positive by both tests all had detectable antibody at the minimum concentration only (12 IU). The dye test confirmed all sera positive by both tests with the exception of three. It also confirmed one of four sera positive by IHA antibody alone and two of six positive by IFA alone. All sera that proved dye test-negative had low antibody concentrations (12 IU) by IHA or IFA. The IHA test, which is commercially available in kit form, would be suitable for use as a screening test during pregnancy. The estimated annual rate of antibody acquisition over the age range 16-40 years is 1.2% per annum with the highest rate in the 36-40 age group (2.5% per annum) and the lowest in the 26-30 age group (0.4% per annum). The clinical history was not significantly different between those with and those without antibody against T gondi but significantly more women in the 36-40 age group had a history of animal contact than those in the 26-30 age group. No conclusive evidence of recent or current infection was found.<\/jats:p>","DOI":"10.1136\/jcp.34.6.659","type":"journal-article","created":{"date-parts":[[2007,6,9]],"date-time":"2007-06-09T00:50:46Z","timestamp":1181350246000},"page":"659-664","source":"Crossref","is-referenced-by-count":8,"title":["Screening for toxoplasmosis in pregnancy."],"prefix":"10.1136","volume":"34","author":[{"given":"E J","family":"Broadbent","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R","family":"Ross","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R","family":"Hurley","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[1981,6,1]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1017\/S0022172400055467","article-title":"Some observations on the epidemiology of toxoplasmosis in Canada","volume":"77","author":"Tizard, I.R.; Fish, N.A.; Quinn, P.J.","year":"1976","unstructured":"Tizard IR, Fish NA, Quinn PJ. Some observations on the epidemiology of toxoplasmosis in Canada. J Hyg 1976; 77:11-21.","journal-title":"J Hyg"},{"key":"ref_2","first-page":"393","article-title":"Serodiagnosis of toxoplasmosis","volume":"40","author":"Jacobs, L.","year":"1976","unstructured":"Jacobs L. Serodiagnosis of toxoplasmosis. In: Cohen A, ed. The Immunology of Parasitic Infections. Oxford: Blackwells, 1976. 3Ben Rachid MS. Sur la technique du sero-diagnostique de la toxoplasmose par hemagglutination passive. Annales de Parisitologie Humaine et Comparee 1965;40:393-401.","journal-title":"Annales de Parisitologie Humaine et Comparee; The Immunology of Parasitic Infections"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1093\/infdis\/130.6.557","article-title":"Prevalence of antibody to toxoplasma among Alaskan natives: relation to exposure to the felidae","volume":"130","year":"1974","unstructured":"Peterson DR, Cooney MK, Beasley PR. Prevalence of antibody to toxoplasma among Alaskan natives: relation to exposure to the felidae. JInfect Dis 1974;130: 557-63.","journal-title":"JInfect Dis"},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"595","DOI":"10.1093\/oxfordjournals.aje.a112265","article-title":"Toxoplasma antibody prevalence in veterinary personnel and a selected population not exposed to cats","volume":"103","author":"Sengbusch, H.G.; Sengbusch, L.A.","year":"1976","unstructured":"Sengbusch HG, Sengbusch LA. Toxoplasma antibody prevalence in veterinary personnel and a selected population not exposed to cats. 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Am J Obstet Gynecol 1972;111:211-8.","journal-title":"Am J Obstet Gynecol"},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1016\/0035-9203(77)90080-3","article-title":"Serological survey for congenital toxoplasma among 4136 pregnant women","volume":"71","author":"Viens, P.; Auger, P.; Villeneuve, R.; Stefanescu-Soare, I.","year":"1977","unstructured":"Viens P, Auger P, Villeneuve R, Stefanescu-Soare I. Serological survey for congenital toxoplasma among 4136 pregnant women. Trans R Soc Trop Med Hyg 1977;71:136-9.","journal-title":"Trans R Soc Trop Med Hyg"},{"key":"ref_8","first-page":"1115","article-title":"Toxoplasmosis in pregnancy","volume":"79","author":"Ruoss, C.F.; Bourne, G.L.","year":"1972","unstructured":"Ruoss CF, Bourne GL. Toxoplasmosis in pregnancy. J Obstet Gynaecol Brit Comm 1972;79:1115-8. OPCS Series FMI No 3 Birth Statistics for 1976. 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