{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,14]],"date-time":"2025-12-14T08:10:31Z","timestamp":1765699831871,"version":"3.48.0"},"reference-count":11,"publisher":"BMJ","issue":"7","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Clin Pathol"],"published-print":{"date-parts":[[1981,7]]},"abstract":"<jats:p>Of 570 patients operated on for hyperparathyroidism, 18 subsequently died (between one day and 12 yr after operation). Pathological findings at necropsy in these patients have been reviewed. Four necropsies on patients with untreated hyperparathyroidism have also been reviewed for comparison. Of these 22 cases, 14 had renal failure at the time of death. This was attributed to the following: nephrocalcinosis 6; chronic glomerulonephritis 4; analgesic nephropathy 1; cystinuria 1; sarcoidosis 1; and polycystic disease 1. Of those with renal failure due to nephrocalcinosis, three had persistent hypercalcaemia after operation; the other three survived only for a short time. There was no evidence of residual nephrocalcinosis producing progressive renal failure if the plasma calcium concentration was corrected. In those with chronic glomerulonephritis, cystinuria, and polycystic disease, the hyperparathyroidism was considered to be tertiary to the renal disease but renal failure was not always present at the time of diagnosis.<\/jats:p>","DOI":"10.1136\/jcp.34.7.730","type":"journal-article","created":{"date-parts":[[2007,6,9]],"date-time":"2007-06-09T00:50:46Z","timestamp":1181350246000},"page":"730-737","source":"Crossref","is-referenced-by-count":9,"title":["Progressive renal failure in surgically treated hyperparathyroidism."],"prefix":"10.1136","volume":"34","author":[{"given":"J","family":"Dixon","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J F","family":"Smith","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[1981,7,1]]},"reference":[{"key":"ref_1","first-page":"74","article-title":"Renal function following parathyroid surgery in primary hyperparathyroidism","volume":"ii:","author":"Britton, D.C.; Thompson, M.H.; Johnston, I.D.A.; Fleming, L.B.","year":"1971","unstructured":"Britton DC, Thompson MH, Johnston IDA, Fleming LB. 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Baltimore: Williams and Wilkins, 1948."},{"key":"ref_4","first-page":"943","article-title":"In: Case records of the Massachusetts General Hospital. Case 29","volume":"268","author":"WT, St Goar","year":"1963","unstructured":"St Goar WT. In: Case records of the Massachusetts General Hospital. Case 29. N Engl J Med 1963;268: 943-53.","journal-title":"N Engl J Med"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1136\/bmj.3.5615.395","article-title":"Tertiary hyperparathyroidism","volume":"iii:","author":"Davies, D.R.; Dent, C.E.; Watson, L.","year":"1968","unstructured":"Davies DR, Dent CE, Watson L. Tertiary hyperparathyroidism. Br MedJ 1968;iii:395-9.","journal-title":"Br MedJ"},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"362","DOI":"10.1136\/jcp.23.4.362","article-title":"Parathyroid adenomas associated with the malabsorption syndrome and chronic renal disease","volume":"23","author":"Smith, J.F.","year":"1970","unstructured":"Smith JF. Parathyroid adenomas associated with the malabsorption syndrome and chronic renal disease. J Clin Pathol 1970;23:362-9.","journal-title":"J Clin Pathol"},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1038\/ki.1978.108","article-title":"Renal insufficiency and hypercalcaemia","volume":"14","author":"Thier, S.O.","year":"1978","unstructured":"Thier SO. Renal insufficiency and hypercalcaemia. Kidney Int 1978;14:194-200.","journal-title":"Kidney Int"},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1097\/00005792-196801000-00003","article-title":"Primary hyperparathyroidism. An analysis of the role of the parathyroid tumour","volume":"47","author":"Lloyd, H.M.","year":"1968","unstructured":"Lloyd HM. Primary hyperparathyroidism. An analysis of the role of the parathyroid tumour. Medicine (Baltimore) 1968;47:53-71.","journal-title":"Medicine (Baltimore)"},{"key":"ref_9","first-page":"231","article-title":"Biochemical aspects of primary hyperparathyroidism: an analysis of 50 cases","volume":"25","author":"Hodgkinson, A.","year":"1963","unstructured":"Hodgkinson A. Biochemical aspects of primary hyperparathyroidism: an analysis of 50 cases. Clin Sci 1963; 25:231-42.","journal-title":"Clin Sci"},{"key":"ref_10","first-page":"306","article-title":"Observations on the kidney after phosphate loading in the rat","volume":"68","author":"Craig, J.M.","year":"1959","unstructured":"Craig JM. Observations on the kidney after phosphate loading in the rat. Archives ofPathology 1959;68:306-15.","journal-title":"Archives ofPathology"},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"628","DOI":"10.1016\/S0140-6736(70)91398-X","article-title":"Extraskeletal calcification complicating oral neutral-phosphate therapy","volume":"ii:","author":"Dudley, F.J.; Blackburn, C.R.B.","year":"1970","unstructured":"Dudley FJ, Blackburn CRB. Extraskeletal calcification complicating oral neutral-phosphate therapy. 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