{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,31]],"date-time":"2025-10-31T07:09:06Z","timestamp":1761894546368,"version":"3.44.0"},"reference-count":16,"publisher":"BMJ","issue":"8","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Clin Pathol"],"published-print":{"date-parts":[[1982,8]]},"abstract":"<jats:p>We studied 14 large bowel resections from patients with a provisional clinical diagnosis of a bleeding vascular lesion of the colon. For the purpose of this study we developed a barium-gelatine vascular injection technique. Six of the 14 cases were proven to be angiodysplasias with an identifiable mucosal vascular ectasia. The pathological findings in these six cases are described. We conclude that angiodysplasia represent a significant cause of lower gastrointestinal haemorrhage in the elderly. It is our opinion that only the mucosa vascular ectasia seen in these cases is histologically diagnostic and that sub-mucosal venous ectasia, while characteristic of angiodysplasia, is non-specific. the differential diagnostic features which will allow the histological distinction of angiodysplasia from other vascular lesions of the colon are discussed.<\/jats:p>","DOI":"10.1136\/jcp.35.8.824","type":"journal-article","created":{"date-parts":[[2007,6,9]],"date-time":"2007-06-09T00:50:46Z","timestamp":1181350246000},"page":"824-829","source":"Crossref","is-referenced-by-count":30,"title":["Angiodysplasias of the colon."],"prefix":"10.1136","volume":"35","author":[{"given":"D J","family":"Pounder","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R","family":"Rowland","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A S","family":"Pieterse","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R","family":"Freeman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R","family":"Hunter","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[1982,8,1]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1007\/BF02551967","article-title":"Angiodysplasia of the colon: a cause of rectal bleeding","volume":"1","author":"Athanasoulis, C.A.; Galdabini, J.J.; Waltman, A.C.; Novelline, R.A.; Greenfield, A.J.; Ezpleta, M.L.","year":"1978","unstructured":"Athanasoulis CA, Galdabini JJ, Waltman AC, Novelline RA, Greenfield AJ, Ezpleta ML. Angiodysplasia of the colon: a cause of rectal bleeding. Cardiovasc Radiol 1978;1:3-13.","journal-title":"Cardiovasc Radiol"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"650","DOI":"10.1016\/S0016-5085(77)80149-2","article-title":"On the nature and aetiology of vascular ectasias of the colon. Degenerative lesions of aging","volume":"72","author":"Boley, S.J.; Sammartano, R.; Adams, A.; Di Biase, A.; Kleinhaus, S.; Sprayregen, S.","year":"1977","unstructured":"Boley SJ, Sammartano R, Adams A, Di Biase A, Kleinhaus S, Sprayregen S. On the nature and aetiology of vascular ectasias of the colon. Degenerative lesions of aging. Gastronenterology 1977;72:650-60.","journal-title":"Gastronenterology"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1007\/BF01574466","article-title":"Haemorrhage from the large bowel with special reference to angiodysplasia and diverticular disease","volume":"2","author":"Welch, C.E.; Christos, A.; Athanasoulis, C.A.; Galdabini, J.J.","year":"1978","unstructured":"Welch CE, Christos A, Athanasoulis CA, Galdabini JJ. Haemorrhage from the large bowel with special reference to angiodysplasia and diverticular disease. World J Surg 1978;2:73-83.","journal-title":"World J Surg"},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1001\/archsurg.1976.01360220077013","article-title":"Arteriovenous malformations of the gastrointestinal tract","volume":"111","author":"Moore, J.D.; Thompson, N.W.; Appelman, H.D.; Foley, D.","year":"1976","unstructured":"Moore JD, Thompson NW, Appelman HD, Foley D. Arteriovenous malformations of the gastrointestinal tract. Arch Surg 1976;111:381-9.","journal-title":"Arch Surg"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"394","DOI":"10.2214\/ajr.126.2.394","article-title":"Analysis of caecal vasculature in the search for vascular malformations","volume":"126","author":"Baer, J.W.; Ryan, S.","year":"1976","unstructured":"Baer JW, Ryan S. Analysis of caecal vasculature in the search for vascular malformations. American Journal of Roentgenology 1976; 126:394-405.","journal-title":"American Journal of Roentgenology"},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1148\/113.1.11","article-title":"Vascular malformations of the right colon as a cause of bleeding in patients with aortic stenosis","volume":"113","author":"Galloway, S.J.; Casarella, W.J.; Shimkin, P.M.","year":"1974","unstructured":"Galloway SJ, Casarella WJ, Shimkin PM. Vascular malformations of the right colon as a cause of bleeding in patients with aortic stenosis. Radiology 1974;113: 11-5.","journal-title":"Radiology"},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"968","DOI":"10.1056\/NEJM198004243021716","article-title":"Calcific aortic stenosis and gastrointestinal bleeding","volume":"302","author":"Love, J.W.; Jahnke, E.J.; Zacharias, D.; Davidson, W.A.; Kidder, W.R.; Luan, L.L.","year":"1980","unstructured":"Love JW, Jahnke EJ, Zacharias D, Davidson WA, Kidder WR, Luan LL. Calcific aortic stenosis and gastrointestinal bleeding. N Engl J Med 1980;302:968.","journal-title":"N Engl J Med"},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1016\/S0046-8177(79)80101-X","article-title":"Vascular ectasias of the right colon in the elderly: a distinct pathologic entity","volume":"10","author":"Mitsudo, S.M.; Boley, S.J.; Brandt, L.J.; Sammartano, Montefusco C.M.; R.J.","year":"1979","unstructured":"Mitsudo SM, Boley SJ, Brandt LJ, Montefusco CM. Sammartano RJ. Vascular ectasias of the right colon in the elderly: a distinct pathologic entity. Hum Pathol 1979;10:585-600.","journal-title":"Hum Pathol"},{"key":"ref_9","first-page":"751","article-title":"Diagnosis and management of obscure gastrointestinal bleeding","volume":"ii:","author":"Tarin, D.; Allison, D.J.; Modlin, I.M.; Neale, G.","year":"1978","unstructured":"Tarin D, Allison DJ, Modlin IM, Neale G. Diagnosis and management of obscure gastrointestinal bleeding. Br Med J 1978;ii:751-4.","journal-title":"Br Med J"},{"key":"ref_10","first-page":"712","article-title":"Arteriovenous malformations of the intestine","volume":"149","author":"Lewi, H.J.E.; Gledhill, T.; Gilmour, H.M.; Buist, T.A.S.","year":"1979","unstructured":"Lewi HJE, Gledhill T, Gilmour HM, Buist TAS. Arteriovenous malformations of the intestine. Surg Gynecol Obstet 1979;149:712-6.","journal-title":"Surg Gynecol Obstet"},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1136\/bmj.1.5222.323","article-title":"Extramural and intramural blood supply of colon","volume":"i:","author":"Griffiths, J.D.","year":"1961","unstructured":"Griffiths JD. Extramural and intramural blood supply of colon. Br Med J 1961;i:323-6.","journal-title":"Br Med J"},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"487","DOI":"10.1016\/0022-3468(73)90211-X","article-title":"Intestinal haemangiomata in childhood and a syndrome for diagnosis: a collective review","volume":"8","author":"Abrahamson, J.; Shandling, B.","year":"1973","unstructured":"Abrahamson J, Shandling B. Intestinal haemangiomata in childhood and a syndrome for diagnosis: a collective review. J Pediatr Surg 1973;8:487-95.","journal-title":"J Pediatr Surg"},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"597","DOI":"10.1056\/NEJM195903192601206","article-title":"Vascular lesion of hereditary haemorrhagic telangiectasia","volume":"260","author":"Bird, R.M.; Jaques, W.E.","year":"1959","unstructured":"Bird RM, Jaques WE. Vascular lesion of hereditary haemorrhagic telangiectasia. N Engl J Med 1959;260:597-9.","journal-title":"N Engl J Med"},{"key":"ref_14","first-page":"569","article-title":"Case records of the Massachusetts General Hospital (case 36-1974)","volume":"291","author":"Scully, R.E.; McNeely, B.U.","year":"1974","unstructured":"Scully RE, McNeely BU. Case records of the Massachusetts General Hospital (case 36-1974). N Engl J Med 1974;291:569-75.","journal-title":"N Engl J Med"},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"530","DOI":"10.1016\/S0016-5085(19)33505-X","article-title":"Gastrointestinal bleeding due to blue rubber bleb naevus syndrome. A case diagnosed by angiography","volume":"61","author":"Baker, A.L.; Kahn, P.C.; Binder, S.C.; Patterson, J.F.","year":"1971","unstructured":"Baker AL, Kahn PC, Binder SC, Patterson JF. Gastrointestinal bleeding due to blue rubber bleb naevus syndrome. A case diagnosed by angiography. Gastroenterology 1971;61:530-4.","journal-title":"Gastroenterology"},{"key":"ref_16","first-page":"17","article-title":"Caecal angiodysplasia as a cause of chronic iron deficiency anaemia. A case report","volume":"57","author":"Shaff, M.I.; Sacks, I.; Stein, D.; Horner, J.; Louw, J.H.","year":"1980","unstructured":"Shaff MI, Sacks I, Stein D, Horner J, Louw JH. Caecal angiodysplasia as a cause of chronic iron deficiency anaemia. A case report. S Afr Med J 1980;57:17-20.","journal-title":"S Afr Med J"}],"container-title":["Journal of Clinical Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/jcp.35.8.824","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,9,25]],"date-time":"2025-09-25T12:13:12Z","timestamp":1758802392000},"score":1,"resource":{"primary":{"URL":"https:\/\/jcp.bmj.com\/lookup\/doi\/10.1136\/jcp.35.8.824"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1982,8]]},"references-count":16,"journal-issue":{"issue":"8","published-online":{"date-parts":[[1982,8,1]]},"published-print":{"date-parts":[[1982,8]]}},"alternative-id":["10.1136\/jcp.35.8.824"],"URL":"https:\/\/doi.org\/10.1136\/jcp.35.8.824","relation":{},"ISSN":["0021-9746","1472-4146"],"issn-type":[{"type":"print","value":"0021-9746"},{"type":"electronic","value":"1472-4146"}],"subject":[],"published":{"date-parts":[[1982,8]]}}}