{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,15]],"date-time":"2025-12-15T04:23:57Z","timestamp":1765772637908,"version":"3.48.0"},"reference-count":12,"publisher":"BMJ","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Clin Pathol"],"published-print":{"date-parts":[[1983,1]]},"abstract":"<jats:p>Two cases in which macroglobulinaemia was associated with intestinal lymphangiectasia are recorded. Immunoperoxidase stains demonstrated a high content of monoclonal IgM in the intestinal lymph. The seven previously recorded examples of this association are reviewed. It is concluded that the concurrence of these two conditions is not merely fortuitous, and that increased viscosity of the lymph consequent on its high IgM content may be important in the pathogenesis of the intestinal lymphangiectasia.<\/jats:p>","DOI":"10.1136\/jcp.36.1.30","type":"journal-article","created":{"date-parts":[[2007,6,9]],"date-time":"2007-06-09T00:50:46Z","timestamp":1181350246000},"page":"30-36","source":"Crossref","is-referenced-by-count":17,"title":["Macroglobulinaemia and intestinal lymphangiectasia: a rare association"],"prefix":"10.1136","volume":"36","author":[{"given":"M","family":"Harris","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"IE","family":"Burton","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"JH","family":"Scarffe","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[1983,1,1]]},"reference":[{"key":"ref_1","unstructured":"There now seem to be sufficient cases on record to establish that the association between macroglobulinaemia, IL, malabsorption and protein-losing enteropathy is not merely fortuitous, although it is extremely rare. However, the pathogenesis of the intestinal lesions is far from clear and various possibilities merit consideration.","article-title":"There now seem to be sufficient cases on record to establish that the association between macroglobulinaemia, IL, malabsorption and protein-losing enteropathy is not merely fortuitous, although it is extremely rare. However, the pathogenesis of the intestinal lesions is far from clear and various possibilities merit consideration"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1111\/j.0954-6820.1944.tb03955.x","article-title":"Incipient myelomatosis or \"essential\" hyperglobulinaemia with fibrinogenopenia - a new syndrome?","volume":"117","author":"Waldenstrom, J.","year":"1944","unstructured":"Waldenstrom J. Incipient myelomatosis or \"essential\" hyperglobulinaemia with fibrinogenopenia - a new syndrome? Acta Med Scand 1944;117:216-47.","journal-title":"Acta Med Scand"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1177\/18.5.315","article-title":"The unlabelled antibody enzyme method of immunohistochemistry. Preparation and properties of the soluble antigen-antibody complex (horseradish peroxidase anti-horseradish peroxidase) and its use in identification of spirochetes","volume":"18","author":"Sternberger, L.A.; PHJr, Hardy; Cuculus, J.J.; Meyer, H.G.","year":"1970","unstructured":"Sternberger LA, Hardy PHJr, Cuculus JJ, Meyer HG. The unlabelled antibody enzyme method of immunohistochemistry. Preparation and properties of the soluble antigen-antibody complex (horseradish peroxidase anti-horseradish peroxidase) and its use in identification of spirochetes. 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Arch Intern Med 1964;114:399-407.","journal-title":"Arch Intern Med"},{"issue":"7","key":"ref_6","first-page":"43","article-title":"Macroglobulinaemia and steatorrhoea: Roentgen and pathologic findings in the intestinal tract","volume":"1969","author":"Khilnani, M.T.; Keller, R.J.; Cuttner, J.","unstructured":"Khilnani MT, Keller RJ, Cuttner J. Macroglobulinaemia and steatorrhoea: Roentgen and pathologic findings in the intestinal tract. Radiol Clin North Am 1969;7:43-55.","journal-title":"Radiol Clin North Am"},{"key":"ref_7","first-page":"64856","article-title":"Intestinal malabsorption in macroglobulinaemia","volume":"16","author":"Beker, S.; Grases, P.J.; Merino, F.; Arends, T.; Guevara, J.","year":"1971","unstructured":"Beker S, Grases PJ, Merino F, Arends T, Guevara J. Intestinal malabsorption in macroglobulinaemia. Am J Dig Dis 1971;16:64856.","journal-title":"Am J Dig Dis"},{"key":"ref_8","first-page":"308","volume-title":"Intestinal involvement in Waldenstrom's macroglobulinaemia. Gastroenterology 1973","volume":"65","author":"Bedine, M.S.; Yardley, J.H.; Elliott, H.L.; Banwell, J.G.; Hendrix, T.R.","unstructured":"Bedine MS, Yardley JH, Elliott HL, Banwell JG, Hendrix TR. Intestinal involvement in Waldenstrom's macroglobulinaemia. Gastroenterology 1973;65:308-15."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"811","DOI":"10.1016\/0002-9343(73)90070-3","article-title":"Malabsorption syndrome with infiltration of the intestinal wall by extracellular monoclonal macroglobulin","volume":"54","author":"Pruzanski, W.; Warren, R.E.; Goldie, J.H.; Katz, A.","year":"1973","unstructured":"Pruzanski W, Warren RE, Goldie JH, Katz A. Malabsorption syndrome with infiltration of the intestinal wall by extracellular monoclonal macroglobulin. Am J Med 1973;54:811-8.","journal-title":"Am J Med"},{"key":"ref_10","first-page":"18997","volume-title":"Macroglobulinaemia and steatorrhoea. Gut 1968","volume":"44","author":"Tubbs, R.R.; McLaughlin, J.P.; El, Winkelman; Deodhar, S.D.; Macroglobulinaemia, Hewlett J.S.; malabsorption. Cleve Clin, Q.","year":"1977","unstructured":"Tubbs RR, McLaughlin JP, Winkelman El, Deodhar SD, Hewlett JS. Macroglobulinaemia and malabsorption. Cleve Clin Q 1977;44:18997. In Bradley J, Hawkins CF, Rowe DS, Stanworth DR. Macroglobulinaemia and steatorrhoea. Gut 1968;9:564-8."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"605","DOI":"10.7326\/0003-4819-77-4-605","article-title":"Immunodeficiency disease and malignancy; various immunologic deficiencies of man and the role of immune processes in the control of malignant disease","volume":"77","author":"Waldmann, T.A.; Strober, W.; Blaese, R.M.","year":"1972","unstructured":"Waldmann TA, Strober W, Blaese RM. Immunodeficiency disease and malignancy; various immunologic deficiencies of man and the role of immune processes in the control of malignant disease. Ann Intern Med 1972;77:605-28.","journal-title":"Ann Intern Med"},{"key":"ref_12","article-title":"Gastrointestinal pathology","author":"Morson, B.; Dawson, I.M.P.","year":"1972","unstructured":"Morson B, Dawson IMP. Gastrointestinal pathology. Oxford: Blackwell, 1972."}],"container-title":["Journal of Clinical Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/jcp.36.1.30","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,12,14]],"date-time":"2025-12-14T11:07:46Z","timestamp":1765710466000},"score":1,"resource":{"primary":{"URL":"https:\/\/jcp.bmj.com\/lookup\/doi\/10.1136\/jcp.36.1.30"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1983,1]]},"references-count":12,"journal-issue":{"issue":"1","published-online":{"date-parts":[[1983,1,1]]},"published-print":{"date-parts":[[1983,1]]}},"alternative-id":["10.1136\/jcp.36.1.30"],"URL":"https:\/\/doi.org\/10.1136\/jcp.36.1.30","relation":{},"ISSN":["0021-9746","1472-4146"],"issn-type":[{"type":"print","value":"0021-9746"},{"type":"electronic","value":"1472-4146"}],"subject":[],"published":{"date-parts":[[1983,1]]}}}