{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,8]],"date-time":"2026-07-08T10:43:20Z","timestamp":1783507400783,"version":"3.55.0"},"reference-count":15,"publisher":"BMJ","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Clin Pathol"],"published-print":{"date-parts":[[1983,4]]},"abstract":"<jats:p>The diagnostic value of the Widal test was assessed in an endemic area. The test was done on 300 normal individuals, 297 non-typhoidal fevers and 275 bacteriologically proven cases of typhoid. Of 300 normal individuals, 2% had an H agglutinin titre of 1\/160 and 5% had an O agglutinin titre of 1\/160. On the basis of these criteria a significant H and\/or O agglutinin titre of 1\/320 or more was observed in 93-97% of typhoid cases and in only 3% of patients with non-typhoidal fever. Of the sera from typhoid cases which gave a significant Widal reaction, the majority (79.9%) showed increases in both H and O agglutinins and 51 of 234 (21.8%) of these sera were collected in the first week of illness. The significance and implications of these findings are discussed.<\/jats:p>","DOI":"10.1136\/jcp.36.4.471","type":"journal-article","created":{"date-parts":[[2007,6,9]],"date-time":"2007-06-09T00:50:46Z","timestamp":1181350246000},"page":"471-475","source":"Crossref","is-referenced-by-count":48,"title":["Significance and value of the Widal test in the diagnosis of typhoid fever in an endemic area."],"prefix":"10.1136","volume":"36","author":[{"given":"T","family":"Pang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S D","family":"Puthucheary","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[1983,4,1]]},"reference":[{"issue":"13","key":"ref_1","first-page":"561","article-title":"Serodiagnostic del la fievre typhoide","volume":"1896","author":"Widal, F.","unstructured":"Widal F. Serodiagnostic del la fievre typhoide. Bull Soc Med Hop Paris 1896;13:561-6.","journal-title":"Bull Soc Med Hop Paris"},{"issue":"206","key":"ref_2","first-page":"839","article-title":"Interpretation of serologic tests for typhoid fever","volume":"1968","author":"Schroeder, S.A.","unstructured":"Schroeder SA. Interpretation of serologic tests for typhoid fever. JAMA 1968;206:839-40.","journal-title":"JAMA"},{"key":"ref_3","first-page":"1","article-title":"A critical assessment of the conventional Widal test in a diagnosis of typhoid and paratyphoid fever","volume":"57","author":"Sen, A.; Saxena, S.N.","year":"1969","unstructured":"Sen A, Saxena SN. A critical assessment of the conventional Widal test in a diagnosis of typhoid and paratyphoid fever. 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Mal J Pathol 1978;1: 11-14.","journal-title":"Mal J Pathol"},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"635","DOI":"10.1128\/AEM.22.4.635-640.1971","article-title":"Microagglutination procedures for febrile agglutination tests","volume":"22","author":"Gaultney, J.B.; Wende, R.D.; Williams, R.P.","year":"1971","unstructured":"Gaultney JB, Wende RD, Williams RP. Microagglutination procedures for febrile agglutination tests. Appl Microbiol 1971;22:635-40.","journal-title":"Appl Microbiol"},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1128\/AEM.23.2.425-426.1972","article-title":"Microtiter plate agglutination test for Salmonella antibodies","volume":"23","author":"Barsoum, I.S.; Awad, A.Y.","year":"1972","unstructured":"Barsoum IS, Awad AY. Microtiter plate agglutination test for Salmonella antibodies. Appl Microbiol 1972;23:425-6.","journal-title":"Appl Microbiol"},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1016\/S0016-5085(19)32194-8","article-title":"Reassessment of the Widal test in the diagnosis of typhoid","volume":"73","author":"Senewiratne, B.; Senewiratne, K.","year":"1977","unstructured":"Senewiratne B, Senewiratne K. Reassessment of the Widal test in the diagnosis of typhoid. Gastroenterology 1977;73:233-6.","journal-title":"Gastroenterology"},{"key":"ref_10","first-page":"161","article-title":"Antibodies and the Aberdeen typhoid outbreak of 1964","volume":"79","author":"Brodie, J.","year":"1977","unstructured":"Brodie J. Antibodies and the Aberdeen typhoid outbreak of 1964. I. The Widal reaction. J Hyg 1977;79:161-80.","journal-title":"I. The Widal reaction. J Hyg"},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1017\/S0022172400034859","article-title":"An international experiment on the Widal reaction","volume":"37","author":"Gardner, A.D.","year":"1937","unstructured":"Gardner AD. An international experiment on the Widal reaction. J Hyg 1937;37:124-42.","journal-title":"J Hyg"},{"key":"ref_12","first-page":"330","article-title":"Anti-salmonella agglutinins in chronic active liver disease","volume":"ii:","author":"Protell, R.L.; Soloway, R.D.; Martin, W.J.; Schoenfield, L.J.; Summerskil, W.H.J.","year":"1971","unstructured":"Protell RL, Soloway RD, Martin WJ, Schoenfield LJ, Summerskil WHJ. Anti-salmonella agglutinins in chronic active liver disease. Lancet 1971;ii:330-2.","journal-title":"Lancet"},{"key":"ref_13","year":"1983","unstructured":"The March 1983 issue"},{"key":"ref_14","article-title":"ISSUE CONTAINS THE FOLLOWING PAPERS","author":"MARCH, T.H.E.","year":"1983","unstructured":"THE MARCH 1983 ISSUE CONTAINS THE FOLLOWING PAPERS"},{"key":"ref_15","article-title":"Raised Coulter mean corpuscular volume in diabetic ketoacidosis, and its underlying association with marked plasma hyperosmolarity LA EVAN-WONG","unstructured":"Raised Coulter mean corpuscular volume in diabetic ketoacidosis, and its underlying association with marked plasma hyperosmolarity LA EVAN-WONG, RJ DAVIDSON"}],"container-title":["Journal of Clinical Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/jcp.36.4.471","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,12,14]],"date-time":"2025-12-14T16:17:55Z","timestamp":1765729075000},"score":1,"resource":{"primary":{"URL":"https:\/\/jcp.bmj.com\/lookup\/doi\/10.1136\/jcp.36.4.471"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1983,4]]},"references-count":15,"journal-issue":{"issue":"4","published-online":{"date-parts":[[1983,4,1]]},"published-print":{"date-parts":[[1983,4]]}},"alternative-id":["10.1136\/jcp.36.4.471"],"URL":"https:\/\/doi.org\/10.1136\/jcp.36.4.471","relation":{},"ISSN":["0021-9746","1472-4146"],"issn-type":[{"value":"0021-9746","type":"print"},{"value":"1472-4146","type":"electronic"}],"subject":[],"published":{"date-parts":[[1983,4]]}}}