{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,28]],"date-time":"2026-03-28T05:39:29Z","timestamp":1774676369312,"version":"3.50.1"},"reference-count":15,"publisher":"BMJ","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Clin Pathol"],"published-print":{"date-parts":[[1984,4]]},"abstract":"<jats:p>A technique using indirect immunoperoxidase antibody was developed for the detection of specific serum IgA antibody to Epstein-Barr virus capsid antigen and early antigen. The IgA technique was compared with an immunofluorescence antibody method. Epstein-Barr virus IgA antibody against viral capsid antigen was detected in all nine patients with Epstein-Barr virus associated undifferentiated nasopharyngeal carcinoma, in 13 (72.2%) of 18 patients with infectious mononucleosis, in 21 (28.3%) of 74 patients with acute lymphoblastic leukaemia, and in six (20%) of 30 patients who had recently had kidney transplants. Epstein-Barr virus IgA antibody against viral capsid antigen was also detected in four (10%) of 40 healthy subjects, but it was not found in any of 20 cord blood samples. Epstein-Barr virus IgA antibody to early antigen was detected in six (66.6%) patients with nasopharyngeal carcinoma and in two (2.7%) patients with acute lymphoblastic leukaemia. The immunoperoxidase assay for Epstein-Barr virus specific IgA was simple, reliable, and rapid and correlated well (r = 0.94) with the immunofluorescence antibody technique.<\/jats:p>","DOI":"10.1136\/jcp.37.4.440","type":"journal-article","created":{"date-parts":[[2007,6,9]],"date-time":"2007-06-09T00:50:46Z","timestamp":1181350246000},"page":"440-443","source":"Crossref","is-referenced-by-count":5,"title":["An immunoperoxidase assay for the detection of specific IgA antibody in Epstein-Barr virus infections."],"prefix":"10.1136","volume":"37","author":[{"given":"R","family":"Cevenini","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M","family":"Donati","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F","family":"Rumpianesi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A","family":"Moroni","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P","family":"Paolucci","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[1984,4,1]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1073\/pnas.59.1.94","article-title":"Relation of Burkitt tumor associated herpes-type to infectious mononucleosis","volume":"59","author":"W, Henle G.Henle; W, Diehl","year":"1968","unstructured":"Henle G. Henle W, Diehl W. Relation of Burkitt tumor associated herpes-type to infectious mononucleosis. Proc Nat Acad Sci USA 1968;59:94-101.","journal-title":"Proc Nat Acad Sci USA"},{"key":"ref_2","first-page":"62","article-title":"Seroepidemiology of the virus","author":"Henle, W.; Henle, G.","year":"1979","unstructured":"Henle W, Henle G. Seroepidemiology of the virus. In: Epstein MA, Achong BG, eds. Epstein-Barr virus. New York: Springer-Verlag, 1979:62-74."},{"key":"ref_3","first-page":"441","article-title":"Infectious mononucleosis and Epstein-Barr virus associated malignancies","volume-title":"Diagnostic procedures for viral, rickettsial and clamydial infections","author":"Henle, W.; Henle, G.; Horwitz, C.A.","year":"1979","unstructured":"Henle W, Henle G, Horwitz CA. Infectious mononucleosis and Epstein-Barr virus associated malignancies. In: Lennette EH, Schmidt NJ, eds. Diagnostic procedures for viral, rickettsial and clamydial infections, 5th ed. 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Detection of antibodies to Epstein-Barr virus capsid antigen by immune adherence hemagglutination. J Clin Microbiol 1982;15:69-73.","journal-title":"J Clin Microbiol"},{"key":"ref_6","first-page":"189200","article-title":"Detection of Epstein-Barr virus antigens and antibodies by peroxidase labelled specific immunoglobulins","volume":"2","author":"Kurstak, E.; deThe G; van deer Hurk","year":"1978","unstructured":"Kurstak E, deThe G, van deer Hurk, et al. Detection of Epstein-Barr virus antigens and antibodies by peroxidase labelled specific immunoglobulins. J Med Virol 1978;2:189200.","journal-title":"J Med Virol"},{"key":"ref_7","first-page":"245","article-title":"Serum antibody profile against herpes-viruses in renal transplant recipients","volume":"61","author":"Carpi, C.; Donati, M.; Musiani, M.; Zerbini, M.; Cevenini, R.; Feletti, C.","year":"1982","unstructured":"Carpi C, Donati M, Musiani M, Zerbini M, Cevenini R, Feletti C. 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