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The measurements were analysed using discriminant analysis. Significant discrimination was found between the two groups. The most important parameters were the number of intermediate layer nuclei per sectioned square millimetre, the mean intermediate layer nuclear area, and the number of nuclei per millimetre of base epithelium. These parameters are consistent with increased cell turnover of the non-ulcerated epithelium before treatment.<\/jats:p>","DOI":"10.1136\/jcp.38.1.44","type":"journal-article","created":{"date-parts":[[2007,6,9]],"date-time":"2007-06-09T00:50:46Z","timestamp":1181350246000},"page":"44-48","source":"Crossref","is-referenced-by-count":18,"title":["Morphometric assessment of reflux oesophagitis in fibreoptic biopsy specimens."],"prefix":"10.1136","volume":"38","author":[{"given":"L R","family":"Jarvis","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J","family":"Dent","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R","family":"Whitehead","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[1985,1,1]]},"reference":[{"key":"ref_1","first-page":"193","article-title":"Effects of substituted benzimidazole (H 149\/94) on gastric acid","volume-title":"secretion in humans. 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Gastroenterology","volume":"86","author":"Konturek, S.J.; Cieszowski, M.; Kwiecien, N.; Konturek, J.; Tasler, J.; Bilski, J.","year":"1984","unstructured":"Konturek SJ, Cieszowski M, Kwiecien N, Konturek J, Tasler J, Bilski J. Effects of Omeprazole, a substituted benzimidazole, on gastrointestinal secretions, serum gastrin, and gastric mucosal blood flow in dogs. Gastroenterology 1984;86:71-7."},{"key":"ref_4","article-title":"Quantitative histology","volume-title":"advances in clinical pathology","author":"Dunnill, M.S.","year":"1968","unstructured":"Dunnill MS. Quantitative histology. In: Dyke JA, ed. Recent advances in clinical pathology. London: Churchill Livingstone, 1968."},{"key":"ref_5","article-title":"Bent DH. Statistical package for the social sciences","author":"Nie, N.H.; Hull, C.H.; Jenkins, J.G.; Steinbrenner, K.","year":"1975","unstructured":"Nie NH, Hull CH, Jenkins JG, Steinbrenner K, Bent DH. Statistical package for the social sciences. 2nd ed. New York: McGraw-Hill Book Company, 1975.","edition":"2nd ed"},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1016\/S0016-5085(75)80046-1","article-title":"The normal human esophageal mucosa: a histological reappraisal","volume":"68","author":"Weinstein, W.M.; Bogoch, E.R.; Bowes, K.L.","year":"1975","unstructured":"Weinstein WM, Bogoch ER, Bowes KL. The normal human esophageal mucosa: a histological reappraisal. Gastroenterology 1975;68:40-4.","journal-title":"Gastroenterology"},{"key":"ref_7","first-page":"163","article-title":"Histological consequences of gastroesophageal","volume-title":"reflux in man. Gastroenterology 1970","volume":"58","author":"Ismail-Beigi, F.; Horton, P.F.; Pope, C.E.","unstructured":"Ismail-Beigi F, Horton PF, Pope CE. Histological consequences of gastroesophageal reflux in man. Gastroenterology 1970; 58:163-74."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"404","DOI":"10.1159\/000198401","article-title":"Sampling error and observer variation in the interpretation of esophageal biopsies","volume":"19","author":"Adami, B.; Eckardt, V.F.; Paulini, K.","year":"1979","unstructured":"Adami B, Eckardt VF, Paulini K. Sampling error and observer variation in the interpretation of esophageal biopsies. Digestion 1979;19:404-10.","journal-title":"Digestion"},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1007\/BF01296251","article-title":"Histological evaluation of chronic gastroesophageal reflux","volume":"29","author":"Knuff, T.E.; Benjamin, S.B.; Worsham, F.; Hancock, J.E.; Castell, D.O.","year":"1984","unstructured":"Knuff TE, Benjamin SB, Worsham F, Hancock JE, Castell DO. Histological evaluation of chronic gastroesophageal reflux. 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