{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,11]],"date-time":"2026-02-11T15:06:16Z","timestamp":1770822376525,"version":"3.50.1"},"reference-count":11,"publisher":"BMJ","issue":"8","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Clin Pathol"],"published-print":{"date-parts":[[1986,8]]},"abstract":"<jats:p>A severe non-dose related skin eruption attributable to treatment with captopril was recently reported: this is distinct from the dose related rashes that have been widely described. Ultrastructural and immunohistochemical studies were carried out to determine in detail the histological features of this eruption: the histological appearances were similar to those found in early mycosis fungoides, so that this disease was erroneously diagnosed in one case. Unlike most other complications resulting from treatment with Captopril, an indistinguishable rash can result from treatment with enalapril, a newer angiotensin converting enzyme inhibitor.<\/jats:p>","DOI":"10.1136\/jcp.39.8.902","type":"journal-article","created":{"date-parts":[[2007,6,9]],"date-time":"2007-06-09T00:50:46Z","timestamp":1181350246000},"page":"902-907","source":"Crossref","is-referenced-by-count":39,"title":["Severe cutaneous reactions to captopril and enalapril; histological study and comparison with early mycosis fungoides."],"prefix":"10.1136","volume":"39","author":[{"given":"P N","family":"Furness","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M J","family":"Goodfield","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K A","family":"MacLennan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A","family":"Stevens","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L G","family":"Millard","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[1986,8,1]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"1111","DOI":"10.1136\/bmj.290.6475.1111","article-title":"Severe cutaneous reaction to","volume":"290","author":"LG, Goodfield M.J.Millard","year":"1985","unstructured":"Goodfield MJ. Millard LG. Severe cutaneous reaction to Captopril. Br Med J 1985;290: 1111.","journal-title":"Captopril. Br Med J"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"851","DOI":"10.1136\/bmj.287.6396.851","article-title":"Captopril; five years on","volume":"287","author":"JIS, Hodsman G.P.Robertson","year":"1983","unstructured":"Hodsman GP. Robertson JIS. Captopril; five years on. Br Med J 1983;287:851-2.","journal-title":"Br Med J"},{"key":"ref_3","first-page":"4","article-title":"Data sheet compendium","volume":"1351","author":"A.B.P.I.","year":"1984","unstructured":"ABPI. Data sheet compendium. London: Datapharm Publications, 1984-5:1351 -4."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"\"151","DOI":"10.1002\/j.1552-4604.1982.tb02156.x","article-title":"Captopril-induced skin eruptions","volume":"22","author":"Luderer JR. Lookingbill DP. Schenck DW. Demers LM, Cohen C, Hayes AH","year":"1982","unstructured":"Luderer JR. Lookingbill DP. Schenck DW. Demers LM, Cohen C, Hayes AH. Captopril-induced skin eruptions. J Clin Pharmacol 1982:22:151-9. 5Gavras 1, Gavras H. Captopril and Enalapril. Ann Intern Med 1983;98:556-7.","journal-title":"J Clin Pharmacol"},{"key":"ref_5","first-page":"41","article-title":"eosinophilia and hyperkalaemia associated with Enalapril","volume":"ii:","author":"Barnes, J.N.; Davies, E.S.; Rash, Gent C.B.","year":"1983","unstructured":"Barnes JN, Davies ES, Gent CB. Rash. eosinophilia and hyperkalaemia associated with Enalapril. Lancet 1983;ii:41.","journal-title":"Lancet"},{"key":"ref_6","first-page":"375","article-title":"Captopril-induced skin eruptions. Clin Res 1980: 28: 589A","volume":"103","author":"Luderer, JR, Lookingbill D.P.Schenck; DW, Demers; LM, Hayes; A.H.","year":"1971","unstructured":"Luderer JR, Lookingbill DP. Schenck DW, Demers LM, Hayes AH. Captopril-induced skin eruptions. Clin Res 1980:28:589A. Lutzner MA, Hobb JW. Horvath P. Ultrastructure of abnormal cells in Sezary syndrome, mycosis fungoides and parapsoriasis en plaque. Artch Dermatol 1971;103:375-86.","journal-title":"Artch Dermatol; Ultrastructure of abnormal cells in Sezary syndrome, mycosis fungoides and parapsoriasis en plaque"},{"key":"ref_7","first-page":"\"57","article-title":"Pathogenesis of cutaneous T cell lymphoma","volume-title":"e disorders of the skin","author":"Edelson, R.L.","year":"1982","unstructured":"Edelson RL. Pathogenesis of cutaneous T cell lymphoma. In: Goos M, Christophers E, eds. LYmp\/hoproliferativ,e disorders of the skin. Berlin: Springer Verlag, 1982:57-64. '\u00b0 Thomas JA, Janossy G. Phenotypic analysis of cells in cutaneous lymphoma; an immunohistologic study. In: Goos M, Christophers E. eds. LVmphoproliferative disorders of the skin. Berlin: Springer Verlag, 1982:128-36."},{"key":"ref_8","first-page":"116","article-title":"The Captoprilinduced eruption","volume":"1980","author":"JJ, Wilkin J.W.Hammond; WM, Kirkendall","unstructured":"Wilkin JW. Hammond JJ, Kirkendall WM. The Captoprilinduced eruption. Arch Dermatol 1980:116:902-5.","journal-title":"Arch Dermatol"},{"issue":"91","key":"ref_9","first-page":"\"65","article-title":"Essential immunology","volume":"1974","author":"Roitt, I.M.","year":"1984","unstructured":"Roitt IM. Essential immunology. 5th ed. Oxford: Blackwell Scientific Publications, 1984:65-77. 4Tan RS-H. Butterworth CM. McLaughlin H, Malka S, Samman PD. Mycosis Fungoides-a disease of antigen persistence. Br J Dermatol 1974:91:607-16.","edition":"5th ed","journal-title":"Br J Dermatol; Mycosis Fungoides-a disease of antigen persistence"},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1016\/S0140-6736(81)90529-8","article-title":"Initial event in mycosis fungoides of the skin is viral infection of epidermis Langerhans'","volume":"ii:","author":"MacKie, R.M.","year":"1981","unstructured":"MacKie RM. Initial event in mycosis fungoides of the skin is viral infection of epidermis Langerhans' cells. Lancet 1981;ii:283-5.","journal-title":"cells. Lancet"},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"587","DOI":"10.1111\/j.1365-2559.1985.tb02842.x","article-title":"The lvmph node in mycosis fungoides: a light and electron microscopy and immunohistological study supporting the Langerhans' cell-retrovirus hypothesis","volume":"9","author":"Slater, D.N.; Rooney, N.; Bleehen, S.; Hamed, A.","year":"1985","unstructured":"Slater DN, Rooney N, Bleehen S, Hamed A. The lvmph node in mycosis fungoides: a light and electron microscopy and immunohistological study supporting the Langerhans' cell-retrovirus hypothesis. Histopathologs. 1985;9:587-621.","journal-title":"Histopathologs"}],"container-title":["Journal of Clinical Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/jcp.39.8.902","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,12,7]],"date-time":"2025-12-07T01:53:38Z","timestamp":1765072418000},"score":1,"resource":{"primary":{"URL":"https:\/\/jcp.bmj.com\/lookup\/doi\/10.1136\/jcp.39.8.902"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1986,8]]},"references-count":11,"journal-issue":{"issue":"8","published-online":{"date-parts":[[1986,8,1]]},"published-print":{"date-parts":[[1986,8]]}},"alternative-id":["10.1136\/jcp.39.8.902"],"URL":"https:\/\/doi.org\/10.1136\/jcp.39.8.902","relation":{},"ISSN":["0021-9746","1472-4146"],"issn-type":[{"value":"0021-9746","type":"print"},{"value":"1472-4146","type":"electronic"}],"subject":[],"published":{"date-parts":[[1986,8]]}}}