{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,6]],"date-time":"2025-12-06T02:48:14Z","timestamp":1764989294461,"version":"3.46.0"},"reference-count":11,"publisher":"BMJ","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Clin Pathol"],"published-print":{"date-parts":[[1987,4]]},"abstract":"<jats:p>Atypical bullous pyoderma gangrenosum was diagnosed during the course of a myeloid malignancy in three patients. One patient had chronic myeloid leukaemia, one acute myeloid leukaemia, and the third, refractory anaemia with excess of blasts. This atypical form of pyoderma gangrenosum has been specifically associated with myeloid malignancies. The atypical appearance of the skin lesions and the clinical context in which they arose caused the true diagnosis to be delayed in all cases. Treatment with steroids was associated with rapid healing of the skin lesion. The histopathological changes in the skin biopsy specimens from these cases were non-specific, and although the histology was considered to be atypical of pyoderma gangrenosum in one case, the unusual features could be attributed to the patient's neutropenia. (Skin biopsy was performed to exclude other specific pathology). Atypical bullous pyoderma gangrenosum is an uncommon association of the myeloid malignancies. It may remain unrecognised and should be considered more often.<\/jats:p>","DOI":"10.1136\/jcp.40.4.387","type":"journal-article","created":{"date-parts":[[2007,6,9]],"date-time":"2007-06-09T00:50:46Z","timestamp":1181350246000},"page":"387-392","source":"Crossref","is-referenced-by-count":42,"title":["Atypical bullous pyoderma gangrenosum associated with myeloid malignancies."],"prefix":"10.1136","volume":"40","author":[{"given":"C R","family":"Hay","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A G","family":"Messenger","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D W","family":"Cotton","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S S","family":"Bleehen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D A","family":"Winfield","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[1987,4,1]]},"reference":[{"key":"ref_1","first-page":"75","article-title":"Neutrophilic dermatosis of myeloproliferative disorders","volume":"9","author":"W, I.Caughman; R, Stern; H, Haynes","year":"1983","unstructured":"I Caughman W, Stern R, Haynes H. Neutrophilic dermatosis of myeloproliferative disorders. J Am Acad Dermatol 1983;9:75 1-8.","journal-title":"J Am Acad Dermatol"},{"key":"ref_2","first-page":"51","article-title":"Cutaneous vasculitis in association with Crohn's disease","volume":"6","author":"Samitz, M.H.; Dana, A.S.; Rosenberg, P.","year":"1970","unstructured":"Samitz MH, Dana AS, Rosenberg P. Cutaneous vasculitis in association with Crohn's disease. Cutis 1970;6:51-6.","journal-title":"Cutis"},{"key":"ref_3","first-page":"194","article-title":"Histopaihology of the skin","author":"Lever, W.F.; Shaumberg-Lever, G.","year":"1983","unstructured":"Lever WF, Shaumberg-Lever G. Histopaihology of the skin. 6th ed. Philadelphia: JB Lippincott Company, 1983:194-6.","edition":"6th ed"},{"key":"ref_4","first-page":"173","article-title":"Pyoderma gangrenosum: a review of 86 patients","volume":"55","author":"Powell, F.C.; Schroeter, A.L.; Su, W.P.D.; Perry, H.O.","year":"1985","unstructured":"Powell FC, Schroeter AL, Su WPD, Perry HO. Pyoderma gangrenosum: a review of 86 patients. Q J Med 1985;55:173-86.","journal-title":"Q J Med"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"932","DOI":"10.1001\/archinte.1979.03630450074024","article-title":"Pyoderma gangrenosum and myeloproliferative disorders: report of a case and review of the literature","volume":"139","author":"Romano, J.; Safai, B.","year":"1979","unstructured":"Romano J, Safai B. Pyoderma gangrenosum and myeloproliferative disorders: report of a case and review of the literature. 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Arch Dermatol 1972;106:901-5.","journal-title":"Arch Dermatol"},{"key":"ref_8","first-page":"455","article-title":"Pyoderma gangrenosum cervical: traitment par echanges plasmatique","volume":"109","author":"Beurey, J.; Canton, P.; Weber, M.","year":"1982","unstructured":"Beurey J, Canton P, Weber M, et al. Pyoderma gangrenosum cervical: traitment par echanges plasmatique. Ann Dermatol Veneriol 1982;109:455-9."},{"issue":"22","key":"ref_9","first-page":"655","article-title":"Pyoderma (ecthyma) gangrenosum: clinical and experimental observations in five cases occurring in adults","volume":"1930","author":"Brunsting, L.A.; Goeckerman, W.H.; O'Leary, P.A.","unstructured":"Brunsting LA, Goeckerman WH, O'Leary PA. Pyoderma (ecthyma) gangrenosum: clinical and experimental observations in five cases occurring in adults. Arch Dermatol 1930;22:655-80.","journal-title":"Arch Dermatol"},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"1518","DOI":"10.1002\/1097-0142(19830415)51:8<1518::AID-CNCR2820510827>3.0.CO;2-U","article-title":"Acute febrile neutrophilic dermatosis (Sweet's syndrome) and myeloproliferative disorders","volume":"51","author":"Cooper, P.H.; Innes, D.J.; Greer, K.E.","year":"1983","unstructured":"Cooper PH, Innes DJ, Greer KE. Acute febrile neutrophilic dermatosis (Sweet's syndrome) and myeloproliferative disorders. Cancer 1983;51:1518-26.","journal-title":"Cancer"},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"1174","DOI":"10.1056\/NEJM198211043071903","article-title":"Circulating immune complexes and the prognosis of acute myeloid leukaemia","volume":"307","author":"Carpentier, N.A.; Fiere, D.M.; Schuh, D.; Ghislaine, T.; Lange, T.A.; Lambert, P.H.","year":"1982","unstructured":"Carpentier NA, Fiere DM, Schuh D, Ghislaine T, Lange TA, Lambert PH. Circulating immune complexes and the prognosis of acute myeloid leukaemia. 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