{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,8]],"date-time":"2026-01-08T15:55:14Z","timestamp":1767887714747,"version":"3.49.0"},"reference-count":15,"publisher":"BMJ","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Clin Pathol"],"published-print":{"date-parts":[[1987,4]]},"abstract":"<jats:p>The role of schistosomes in the pathologenesis of acute appendicitis in an endemic area was investigated. Of 1600 appendicectomies received in our laboratory, 26 showed appendiceal schistosomiasis, which prompted what we believe to be the first detailed histopathological evaluation of all appendices with schistosomal infestation, without prior knowledge of the clinical and operative diagnoses. The results suggest that there are two types of schistosomal appendicitis, each with distinct clinicopathological features and different pathogenetic mechanisms. They could be called obstructive and granulomatous schistosomal acute appendicitis, respectively.<\/jats:p>","DOI":"10.1136\/jcp.40.4.424","type":"journal-article","created":{"date-parts":[[2007,6,9]],"date-time":"2007-06-09T00:50:46Z","timestamp":1181350246000},"page":"424-428","source":"Crossref","is-referenced-by-count":34,"title":["Appendicular schistosomiasis: a cause of clinical acute appendicitis?"],"prefix":"10.1136","volume":"40","author":[{"given":"M B","family":"Satti","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D M","family":"Tamimi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M O","family":"Al Sohaibani","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A","family":"Al Quorain","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[1987,4,1]]},"reference":[{"issue":"8","key":"ref_1","first-page":"167","article-title":"Study of the so called ectopic lesions in schistosoma mansoni infections. 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Florida: CRC, 1982."},{"key":"ref_4","article-title":"Ackerman's surgicalpathology volume","author":"Rosai, J.","year":"1981","unstructured":"Rosai J. Ackerman's surgicalpathology volume. 6th Ed. St Louis: CV Mosby Company, 1981.","edition":"6th Ed"},{"key":"ref_5","article-title":"Schistosoma mansoni soluble egg antigen. Biochemistry of parasites and host parasite relationships","author":"Pelley, R.P.; Pelley, R.J.","unstructured":"Pelley RP, Pelley RJ. In: Van den Bossche, ed. Schistosoma mansoni soluble egg antigen. Biochemistry of parasites and host parasite relationships. Amsterdam: Biomedical Press, 1976:283."},{"key":"ref_6","first-page":"369","article-title":"Endogenous desensitization: changing host granulomatous response to schistosome eggs at different stages of infection with Schistosoma mansoni","volume":"52","author":"Domingo, E.O.; Warren, K.S.","year":"1968","unstructured":"Domingo EO, Warren KS. Endogenous desensitization: changing host granulomatous response to schistosome eggs at different stages of infection with Schistosoma mansoni. Am J Pathol 1968;52:369-79.","journal-title":"Am J Pathol"},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"917","DOI":"10.4269\/ajtmh.1977.26.917","article-title":"Immune responses during human schistosomiasis mansoni. Regulatory effects of patients' sera on human lymphocytes blastogenic responses to schistosome antigen preparation","volume":"26","author":"Colley, D.G.; Heiny, S.E.; Bartholomew, R.K.; Cook, J.A.","year":"1977","unstructured":"Colley DG, Heiny SE, Bartholomew RK, Cook JA. Immune responses during human schistosomiasis mansoni. Regulatory effects of patients' sera on human lymphocytes blastogenic responses to schistosome antigen preparation. 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Dis Colon Rectum 1981;24:432-6.","journal-title":"Dis Colon Rectum"},{"issue":"1","key":"ref_12","first-page":"149","article-title":"Tuberculosis of the appendix","volume":"28","author":"Koster, H.; Kasman, L.P.","year":"1934","unstructured":"Koster H, Kasman LP. Tuberculosis of the appendix. Arch Surg 1934;28:1 149-65.","journal-title":"Arch Surg"},{"key":"ref_13","first-page":"34","article-title":"Primary tuberculosis appendicitis","volume":"4","author":"Kini, M.G.","year":"1942","unstructured":"Kini MG. Primary tuberculosis appendicitis. Indian J Surg 1942;4:34-47.","journal-title":"Indian J Surg"},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1056\/NEJM195202282460903","article-title":"Tuberculosis localized in the vermiform appendix","volume":"246","author":"Morrison, H.; Mixter, C.G.; Schlesinger, M.J.; Ober, W.B.","year":"1952","unstructured":"Morrison H, Mixter CG, Schlesinger MJ, Ober WB. Tuberculosis localized in the vermiform appendix. N Engl J Med 1952;246:329-31.","journal-title":"N Engl J Med"},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"1603","DOI":"10.1001\/archinte.1983.00350080125027","article-title":"Sarcoidosis with involvement of the appendix","volume":"143","author":"Clarke, L.; Pollett, W.; Chittal, S.; Mu, Ra","year":"1983","unstructured":"Clarke L, Pollett W, Chittal S, Ra Mu. Sarcoidosis with involvement of the appendix. 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