{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,2]],"date-time":"2025-11-02T16:24:47Z","timestamp":1762100687200,"version":"3.44.0"},"reference-count":14,"publisher":"BMJ","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Clin Pathol"],"published-print":{"date-parts":[[1988,1]]},"abstract":"<jats:p>Between 1979 and 1985 surgical resections from 680 cases of primary breast cancer were examined histologically. The patients were divided into four groups: (i) patients aged between 45 and 69 years who had been screened (n = 316); (ii) those younger than 45 who had not been screened (n = 55); (iii) those aged between 45 and 69 who had not been screened (n = 104); and (iv) those older than 69 who had not been screened (n = 205). The material was compared in terms of the association between in situ and invasive carcinoma. There was a low incidence of lobular carcinoma in situ (LCIS) in all groups and a high incidence of ductal carcinoma in situ (DCIS) which declined with age. Ninety nine group i patients had in situ carcinoma or early invasive carcinoma (less than 1 cm in diameter) compared with 19 of group iii cases. Screened patients had fewer multicentric cancers and a lower incidence of large invasive cancer compared with unscreened patients. Group ii patients had a higher incidence of whole quadrant in situ carcinoma, multiple cancer, and lymph node metastases. Group iv patients had a lower incidence of in situ cancer, and more low grade cancer than the other groups. Cases were divided into four types on the basis of this analysis.<\/jats:p>","DOI":"10.1136\/jcp.41.1.3","type":"journal-article","created":{"date-parts":[[2007,6,9]],"date-time":"2007-06-09T00:50:46Z","timestamp":1181350246000},"page":"3-11","source":"Crossref","is-referenced-by-count":14,"title":["Topographical and histological presentation of mammographic pathology in breast cancer."],"prefix":"10.1136","volume":"41","author":[{"given":"N M","family":"Gibbs","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[1988,1,1]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"1307","DOI":"10.1111\/j.1365-2559.1985.tb02812.x","article-title":"cancer in a screened and unscreened population investigated by mammography","volume":"9","year":"1985","unstructured":"cancer in a screened and unscreened population investigated by mammography. Histopathology 1985;9:1307-18.","journal-title":"Histopathology"},{"key":"ref_2","article-title":"Histological typing of breast Iwnours","author":"Scarff, R.W.; Torloni, H.","year":"1968","unstructured":"Scarff RW, Torloni H. Histological typing of breast Iwnours. Geneva; WHO, 1968:19."},{"key":"ref_3","first-page":"161","article-title":"Lobular carcinoma ofthe breast in-situ and infiltrating","author":"Wheeler, J.E.; Enterline, M.T.","year":"1976","unstructured":"Wheeler JE, Enterline MT. Lobular carcinoma ofthe breast in-situ and infiltrating. In Somers SC, ed. Pathology annual, New York: Appleton Century Crofts, 1976:161-88."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1111\/j.1365-2559.1982.tb02712.x","article-title":"Infiltrating lobular carcinoma ofthe breast","volume":"6","author":"Dixon, J.M.; Anderson, T.J.; Page, D.L.; Lee, D.; Duffy, S.W.","year":"1982","unstructured":"Dixon JM, Anderson TJ, Page DL, Lee D, Duffy SW. Infiltrating lobular carcinoma ofthe breast. Histopathology 1982;6: 149-61.","journal-title":"Histopathology"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"600","DOI":"10.1097\/00000658-196304000-00016","article-title":"Age and menstrual status as prognostic factors in carcinoma of the breast","volume":"157","author":"Klcinfeld, G.; Haagensen, C.; Cooley, E.","year":"1963","unstructured":"Klcinfeld G, Haagensen C, Cooley E. Age and menstrual status as prognostic factors in carcinoma of the breast. Ann Surg 1963;157:600-5.","journal-title":"Ann Surg"},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1016\/S0009-9260(81)80168-7","article-title":"The progress of breast carcinoma in women aged less than 40 years","volume":"32","author":"Ruberio, G.G.; Swindell, R.","year":"1981","unstructured":"Ruberio GG, Swindell R. The progress of breast carcinoma in women aged less than 40 years. Clin Radiol 1981;32:231-6.","journal-title":"Clin Radiol"},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"644","DOI":"10.1038\/bjc.1970.78","article-title":"Analysis of clinical and histopathological features in 101 cases of carcinoma of the breast in women under 35 years of age","volume":"24","author":"Brightmore, T.G.J.; Greening, W.P.; Hamblin, I.","year":"1970","unstructured":"Brightmore TGJ, Greening WP, Hamblin I. Analysis of clinical and histopathological features in 101 cases of carcinoma of the breast in women under 35 years of age. Br J Cancer 1970;24:644-69.","journal-title":"Br J Cancer"},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"553","DOI":"10.1097\/00007611-198405000-00006","article-title":"Carcinoma of the breast in the extremes of age","volume":"77","author":"Adkins, R.B.; Whiteneck, J.M.; Woltering, E.","year":"1984","unstructured":"Adkins RB, Whiteneck JM, Woltering E. Carcinoma of the breast in the extremes of age. South Africa MedJ 1984;77:553-9.","journal-title":"South Africa MedJ"},{"key":"ref_9","first-page":"23","article-title":"Breast cancer in 120 women under 35 years old","volume":"0","author":"Max, M.H.; Klamer, T.W.","year":"1984","unstructured":"1 Max MH, Klamer TW. Breast cancer in 120 women under 35 years old. Am J Surg 1984;S0:23-5.","journal-title":"Am J Surg"},{"key":"ref_10","first-page":"133","article-title":"Breastcarcinoma in women 35 years of age or younger","author":"ML, Rosen P.P.Lesser; DW, Kinne; EJ, Beattie","year":"1984","unstructured":"Rosen PP. Lesser ML, Kinne DW, Beattie EJ. Breastcarcinoma in women 35 years of age or younger. Ann Surg 1984;199:133-42."},{"key":"ref_11","first-page":"898902","article-title":"Age as a prognostic factor in breast cancer","volume":"56","year":"1985","unstructured":"Adami H-O, Malker B, Meirik 0, Persson I, Bergvist L, Stone B. Age as a prognostic factor in breast cancer. Cancer 1985;56:898902.","journal-title":"Cancer"},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"606","DOI":"10.1016\/S0002-9610(85)80136-7","article-title":"Carcinoma of the breast in women 80 years of age and older: still a lethal disease","volume":"149","author":"Robins, RE, Lee 0","year":"1985","unstructured":"Robins RE, Lee 0. Carcinoma of the breast in women 80 years of age and older: still a lethal disease. Am JSurg 1985;149:606-9.","journal-title":"Am JSurg"},{"key":"ref_13","first-page":"356","article-title":"Invasive breast cancerthe tip of an iceberg","volume":"65","author":"J, I.Cahill; NM, Gibbs; PS, Boulter; J, Brient","year":"1983","unstructured":"I Cahill J, Gibbs NM, Boulter PS, Brient J. Invasive breast cancerthe tip of an iceberg. Ann R Coll Surg Eng 1983;65:356-59.","journal-title":"Ann R Coll Surg Eng"},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"647","DOI":"10.1111\/j.1365-2559.1982.tb02757.x","article-title":"Large paraffin sections and chemical clearance of axillary tissues as a routine procedure in the pathological examination of the breast","volume":"6","author":"Gibbs, N.M.","year":"1982","unstructured":"Gibbs NM. Large paraffin sections and chemical clearance of axillary tissues as a routine procedure in the pathological examination of the breast. Histopathology 1982;6:647-60.","journal-title":"Histopathology"}],"container-title":["Journal of Clinical Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/jcp.41.1.3","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,9,25]],"date-time":"2025-09-25T11:07:33Z","timestamp":1758798453000},"score":1,"resource":{"primary":{"URL":"https:\/\/jcp.bmj.com\/lookup\/doi\/10.1136\/jcp.41.1.3"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1988,1]]},"references-count":14,"journal-issue":{"issue":"1","published-online":{"date-parts":[[1988,1,1]]},"published-print":{"date-parts":[[1988,1]]}},"alternative-id":["10.1136\/jcp.41.1.3"],"URL":"https:\/\/doi.org\/10.1136\/jcp.41.1.3","relation":{},"ISSN":["0021-9746","1472-4146"],"issn-type":[{"type":"print","value":"0021-9746"},{"type":"electronic","value":"1472-4146"}],"subject":[],"published":{"date-parts":[[1988,1]]}}}