{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,11]],"date-time":"2026-02-11T15:29:41Z","timestamp":1770823781482,"version":"3.50.1"},"reference-count":10,"publisher":"BMJ","issue":"10","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Clin Pathol"],"published-print":{"date-parts":[[1988,10]]},"abstract":"<jats:p>Two examples of intraplacental choriocarcinoma are described. Both were small and had arisen in otherwise normal third trimester placentas. The covering mantle of many of the villi adjacent to the choriocarcinomas was formed, either focally or wholly, of neoplastic trophoblastic tissue: it is only at this stage of the development of a choriocarcinoma that villous structures are present, and a study of these cases adds further evidence for an origin of choriocarcinoma from villous trophoblast. Intraplacental choriocarcinomas can give rise to both maternal and fetal metastases during pregnancy, and it is suggested that such lesions also serve as an origin for those choriocarcinomas which follow a term pregnancy.<\/jats:p>","DOI":"10.1136\/jcp.41.10.1085","type":"journal-article","created":{"date-parts":[[2007,6,9]],"date-time":"2007-06-09T00:50:46Z","timestamp":1181350246000},"page":"1085-1088","source":"Crossref","is-referenced-by-count":55,"title":["Intraplacental choriocarcinoma: a report of two cases."],"prefix":"10.1136","volume":"41","author":[{"given":"H","family":"Fox","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R N","family":"Laurini","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[1988,10,1]]},"reference":[{"key":"ref_1","first-page":"1045","article-title":"Gestational trophoblastic disease","volume-title":"Taylor's textbook of obstetrical and gynaecological pathology","author":"Elston, C.W.","year":"1987","unstructured":"Elston CW. Gestational trophoblastic disease. In: Fox H, ed. Haines and Taylor's textbook of obstetrical and gynaecological pathology. Edinburgh: Churchill Livingstone, 1987:1045-78."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1097\/00004347-198403010-00009","article-title":"Immunocytochemical localisation of placental lactogen and chorionic gonadotropin in the normal placenta and trophoblastic tumors with emphasis on intermediate trophoblast and the placental site trophoblastic tumor","volume":"3","author":"Kurman, R.J.; Young, R.H.; Norris, H.J.; Lawrence, W.D.; Scully, R.E.","year":"1984","unstructured":"Kurman RJ, Young RH, Norris HJ, Lawrence WD, Scully RE. Immunocytochemical localisation of placental lactogen and chorionic gonadotropin in the normal placenta and trophoblastic tumors with emphasis on intermediate trophoblast and the placental site trophoblastic tumor. Int J Gynecol Pathol 1984; 3: 101-21.","journal-title":"Int J Gynecol Pathol"},{"key":"ref_3","first-page":"96","article-title":"Choriocarcinoma: an \"incidental finding\" within a tenn placenta","volume":"21","author":"Driscoll, S.G.","year":"1963","unstructured":"Driscoll SG. Choriocarcinoma: an \"incidental finding\" within a tenn placenta. Obstet Gynecol 1963;21:96-101.","journal-title":"Obstet Gynecol"},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"692","DOI":"10.1016\/0002-9378(66)90402-9","article-title":"Early development of choriocarcinoma","volume":"94","author":"BrewerJI, Gerbie A.B.","year":"1966","unstructured":"BrewerJI, Gerbie AB. Early development of choriocarcinoma. Am J Obstet Gynecol 1966;94:692-710.","journal-title":"Am J Obstet Gynecol"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1016\/S0065-230X(08)60931-8","article-title":"Gestational trophoblastic disease: origin of choriocarcinoma, invasive mole and choriocarcinoma associated with hydatidiform mole, and some immunologic aspects","volume":"27","author":"Brewer, J.I.; Torok, E.E.; Kahan, B.D.; Stanhope, C.R.; Halpern, B.","year":"1978","unstructured":"Brewer JI, Torok EE, Kahan BD, Stanhope CR, Halpern B. Gestational trophoblastic disease: origin of choriocarcinoma, invasive mole and choriocarcinoma associated with hydatidiform mole, and some immunologic aspects. 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Gynecol Oncol 1981;11:348-63.","journal-title":"Gynecol Oncol"},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"711","DOI":"10.1016\/0002-9378(84)90552-0","article-title":"Choriocarcinoma associated with term gestation","volume":"148","author":"Olive, D.L.; Lurain, JR, Brewer; J.I.","year":"1984","unstructured":"Olive DL, Lurain JR, Brewer JI. Choriocarcinoma associated with term gestation. Am J Obstet Gynecol 1984;148:711-6.","journal-title":"Am J Obstet Gynecol"},{"key":"ref_9","first-page":"13","article-title":"Choriocarcinoma in mother and fetus","volume":"24","author":"Tsukamoto, N.; Matsumura, M.; Matsukuma, K.; Kamura, T.; Baba, K.","year":"1986","unstructured":"Tsukamoto N, Matsumura M, Matsukuma K, Kamura T, Baba K. Choriocarcinoma in mother and fetus. Gynecol Oncol 1986;24: 13-9.","journal-title":"Gynecol Oncol"},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"1000","DOI":"10.1111\/j.1471-0528.1966.tb06129.x","article-title":"The classification ofmalignant growths ofthe chorion","volume":"73","author":"Tow, W.S.H.","year":"1966","unstructured":"Tow WSH. The classification ofmalignant growths ofthe chorion. Journal of Obstetrics and Gynaecology of the British Commomwealth 1966;73:1000-1.","journal-title":"Journal of Obstetrics and Gynaecology of the British Commomwealth"}],"container-title":["Journal of Clinical Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/jcp.41.10.1085","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,12,14]],"date-time":"2025-12-14T11:36:38Z","timestamp":1765712198000},"score":1,"resource":{"primary":{"URL":"https:\/\/jcp.bmj.com\/lookup\/doi\/10.1136\/jcp.41.10.1085"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1988,10]]},"references-count":10,"journal-issue":{"issue":"10","published-online":{"date-parts":[[1988,10,1]]},"published-print":{"date-parts":[[1988,10]]}},"alternative-id":["10.1136\/jcp.41.10.1085"],"URL":"https:\/\/doi.org\/10.1136\/jcp.41.10.1085","relation":{},"ISSN":["0021-9746","1472-4146"],"issn-type":[{"value":"0021-9746","type":"print"},{"value":"1472-4146","type":"electronic"}],"subject":[],"published":{"date-parts":[[1988,10]]}}}