{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,20]],"date-time":"2026-03-20T14:47:16Z","timestamp":1774018036376,"version":"3.50.1"},"reference-count":14,"publisher":"BMJ","issue":"8","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Clin Pathol"],"published-print":{"date-parts":[[1988,8]]},"abstract":"<jats:p>A quantitative histological analysis of the major salivary glands was carried out at necropsy in 28 alcoholics and in a series of age and sex matched controls. The findings were related to the different types of histologically diagnosed liver disease present. Significant quantitative changes of salivary gland structure were noted in cirrhosis but not in other forms of alcoholic liver disease. In cirrhotic subjects the parotid contained proportionally more adipose but less acinar tissues than in controls. The submandibular gland showed a proportional increase in adiposity and reduction in fibrovascular tissues but no noticeable reduction in its acinar proportional volume. Neither grossly detectable parotid enlargement nor acinar hypertrophy, a feature which has previously been noted as characteristic of alcoholic sialadenosis, were evident in this series. These findings provide little structural support for the reportedly increased secretory capacity of salivary glands in chronic alcohol abuse.<\/jats:p>","DOI":"10.1136\/jcp.41.8.837","type":"journal-article","created":{"date-parts":[[2007,6,9]],"date-time":"2007-06-09T00:50:46Z","timestamp":1181350246000},"page":"837-840","source":"Crossref","is-referenced-by-count":42,"title":["Histological analysis of parotid and submandibular glands in chronic alcohol abuse: a necropsy study."],"prefix":"10.1136","volume":"41","author":[{"given":"J","family":"Scott","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J","family":"Burns","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E A","family":"Flower","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[1988,8,1]]},"reference":[{"key":"ref_1","first-page":"1","article-title":"Alcohol and disease","volume":"38","author":"Sherlock, S.","year":"1982","unstructured":"Sherlock S. Alcohol and disease. Br Med Bull 1982;38:1-2.","journal-title":"Br Med Bull"},{"key":"ref_2","first-page":"137","article-title":"Aetiological factors in mouth cancer. An approach to its prevention","volume":"1","author":"Wynder, E.L.; Bross, I.J.","year":"1957","unstructured":"Wynder EL, Bross IJ. Aetiological factors in mouth cancer. An approach to its prevention. Br Med J 1957;i: 1 137-43.","journal-title":"Br Med J"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"654","DOI":"10.1111\/j.1600-0714.1985.tb00543.x","article-title":"A histological analysis of the early effects of alcohol and tobacco usage on human lingual epithelium","volume":"14","author":"ValentineJA, Scott J.; CR, West; CA, St Hill","year":"1985","unstructured":"ValentineJA, Scott J, West CR, St Hill CA. A histological analysis of the early effects of alcohol and tobacco usage on human lingual epithelium. 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A quantitative study of histological changes in the human parotid gland occurring with adult age. J Oral Pathol 1987;16:505-10.","journal-title":"J Oral Pathol"},{"issue":"8","key":"ref_14","first-page":"604","article-title":"Parotid function in chronic alcoholism without overt liver disease","volume":"15","author":"Vicary, K.; Baxter, P.; Scott, J.","year":"1988","unstructured":"Vicary K, Baxter P, Scott J. Parotid function in chronic alcoholism without overt liver disease. J Dent Res 1988;67: 15 Gliner JA, Horvath SM, Browe AC. Circulatory changes due to alcohol, anxiety and their interactions. Proc Soc Exp Biol Med 1978;15S8:604-8.","journal-title":"J Dent Res; and their interactions. Proc Soc Exp Biol Med; 67: 15 Gliner JA, Horvath SM, Browe AC. Circulatory changes due to alcohol, anxiety"}],"container-title":["Journal of Clinical Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/jcp.41.8.837","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,12,14]],"date-time":"2025-12-14T12:09:13Z","timestamp":1765714153000},"score":1,"resource":{"primary":{"URL":"https:\/\/jcp.bmj.com\/lookup\/doi\/10.1136\/jcp.41.8.837"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1988,8]]},"references-count":14,"journal-issue":{"issue":"8","published-online":{"date-parts":[[1988,8,1]]},"published-print":{"date-parts":[[1988,8]]}},"alternative-id":["10.1136\/jcp.41.8.837"],"URL":"https:\/\/doi.org\/10.1136\/jcp.41.8.837","relation":{},"ISSN":["0021-9746","1472-4146"],"issn-type":[{"value":"0021-9746","type":"print"},{"value":"1472-4146","type":"electronic"}],"subject":[],"published":{"date-parts":[[1988,8]]}}}